Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0018681 (headache)
 56,091 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

During EST of schizophrenic (with a prevalent depressive symptomatology) and manic-depressive patients refractory to medicinal therapy, it was possible to find the following conditions. There was a definite advantage in the use of a narcotizing preparation such as epontal with a relaxant listenon compared to a tiopenthal narcosis. This may be due to a short-time narcotic effect of epontal, the absence of postnarcotic symptoms such as expressed apathy, weakness, headaches, which can be observed during 2-3 hours, following tiopenthal narcosis.
 ...
PMID:[A method of carrying out ECT under anesthesia with relaxants]. 93 57

The widespread use of organophosphate pesticides creates the possibility of excessive exposure of migrant farm workers to these compounds. Blood cholinesterase determinations were used to compare the organophosphate pesticide exposure of 57 migrant farm workers with that of 35 controls. Frequently reported symptoms of the farm workers which might be related to pesticide exposure were also studied, including headaches, dizziness, loss of weight, nausea, and a general feeling of weakness or loss of energy. Significantly depressed cholinesterase activities were found in the farm workers, with 10.5% of the farm workers having values below the lower limit of normal. There was no significant relationship between frequently reported symptoms of the farm workers and depressed cholinesterase levels.
 ...
PMID:Depressed cholinesterase activities among farm workers in New Jersey. 95 12

Stab wound of the spinal cord caused by accident occurred in the home life is rare absolutely. One case of stab wound of the cervical spinal cord caused by penetrated and retained glass fragment within the spinal canal was reported. A 30-year-old woman was hospitarized on August 16, 1971. with complaint of left hemiparesis, gait disturbance and sensory impairment on the right side. A glass door fell down on the patient's neck on April 14, 1971. and one glass fragment was removed from the patient's left neck by one of the patient's family and no immediate spinal cord symptom appeared and no physician was consulted at that time. One and a half month after the injury the patient rod a motor bicycle and pain and severe stiffness in the shoulder and neck, and headache. These subjective symptom disappeared by rest and same subjective symptom repeated in following five days. Three and a half months after the injury the patient found sensation loss in the right foot and gait distrubance appeared. After the sensory impairment extended to the cervical level which was accompanied by left hemiparesis. On examination, the patient was found to have merked weakness of left limbs, spastic gait and severe impairment of touchpain- and thermosensation below the fifth cervical level but deep sensation was preserved. All tendon reflexes showed marked exaggeration and pathological reflexes were proved. Roentgenograms of the cervical spine revealed a long triangular glass fragment which had been retained in the spinal canal between the first and second cervical vertebrae. The air myelogram suggested the glass fragment had transfixed the cervical spinal cord. Laminectomy was performed and the glass fragment which had a shape of a sharp pointed surgical knife was removed by gentle move in the opposite direction of invation. Following removal of the foreign body, the patient's left hemiparesis recovered to normal state at four months after the operation and right sensory impairment also improved. The cervical spinal cord may be injured in the following way: the right lateral spinothalamic tract may be injured by the skewer injury due to glass fragment but injury of the left same tract may be avoided because of oblique direction of penetration of the glass fragment in the spinal cord. On the other hand, the left pyramidal tract may be compressed by glass fragment and not injured, because left hemiparesis recovered very well postoperatively.
 ...
PMID:[Transfixion of cervical cord by a glass fragment--report of a case (author's transl)]. 98 74

Cystic changes are rare in meningioma. The authors reported two cases of the cystic meningioma. 1) The first case was 56-year-old female, whose complaints were motor weakness and hypesthesia on the right side. At the operation, a hen egg-sized tumor with a large cyst was removed totally from the left frontoparietal mid-convexity. Multiple cystic cavities were contained in the tumor. Histologically the tumor was compatible with meningocytic meningioma with angiomatous component and showed numerous myxomatous degeneration and swollen vessel-walls. 2) The second case was 17-year-girl complaining of headache, blurred vision, right hemiparesis and episodes of Jacksonian seizure. At the operation, a goose egg-sized tumor in the left parietal lobe was removed and the tumor contained a large cyst. Histologically the tumor was a malignant meningioma, associating with relatively fresh necroses adjacent the cyst. 3) The pathogenesis of the cystic changes in meningioma was discussed.
 ...
PMID:[Cystic meningioma--report of two cases (author's transl)]. 98 75

The authors report the case of an eight-year-old girl hospitalised for severe headache with paroxysmal left otalgia, vomiting, aprexia, paralysis of the left 6 th cranial nerve and slight left facial weakness. Left carotid arteriography revealed a very large aneurysm of the internal carotid, involving its entire intra-petrous and intra-cavernous course. Treatment consisted of ligation of the internal carotid in the neck. Postoperative angiographic studies showed complete exclusion of the aneurysm, and it was unecessary to carry out "trapping" by ligation of the supra-cavernous carotid, as had initially been envisaged. The postoperative course was uneventful : immediate disappearance of otalgia, secondary complete recovery of the oculo-motor involvement and facial paresis. The absence of any infections or traumatic past history, together with the young age of the patient, represent arguments in favour of the congenital origin of this intra-petrous carotid aneurysm.
 ...
PMID:[Case of giant intra-petrous and intra-cavernous internal carotid aneurysm in a child]. 103 Jul 83

A syndrome of alveolar hypoventilation has been identified in a group of patients with bilateral diaphragm paralysis. Eight patients were studied in whom diaphragm weakness had been suggested by paradoxical (inward) movement of the abdominal wall on inspiration, of whom seven had evidence of a generalized neuromuscular disorder. Diaphragm function was assessed quantitatively by measurement of the change in transdiaphragmatic pressure during a maximum inspiration (deltaPDi). In five patients, deltaPDi was zero and in the others ranged from 2-6 cm H2O (normal greater than 25 cm H2O) indicating paralysis and severe weakness in the respective groups. Fluoroscopy of the diaphragm was found to give misleading results, and the resons for this are considered. Vital capacity ranged from 65-30 per cent of the predicted normal in the upright posture, typically falling by about a half in the supine posture. Alveolar hypoventilation was present in five patients when supine and in six when asleep, the deterioration in blood gases associated with sleep generally being much greater in these patients than in normal subjects. Respiratory rate was significantly greater than age-matched controls. The ventilatory response to CO2 was impaired. The PCO2 could be brought to normal levels by voluntary hyperventilation, and the unreliability of voluntary respiratory manoeuvres of this kind as indices of ventilatory reserve is emphasized. Alveolar hypoventilation was associated with disturbed sleep, morning headache and day-time fatigue. Symptomatic benefit was achieved by the use of a cuirass respirator at night.
 ...
PMID:Diaphragm function and alveolar hypoventilation. 106 15

In two siblings with limb-girdle muscle weakness and episodic headaches and vomiting from early childhood, progressive neurologic degeneration later developed, and both children died. In one child, corticosteroids induced improvement in both cerebral and muscular symptoms that lasted 1 year. This patient had elevated blood, urine, and spinal fluid lactate levels, together with increased cardiac output and oxygen consumption at rest. Several muscle fibers were characterized by a "ragged red" appearance with the trichrome stain. Subsarcolemmal and intermyofibrillar excess of mitochondrial oxidative enzyme reaction product was correlated with abnormal mitochondrial aggregates by electron microscopy. The brain revealed focal areas of cortical degeneration and necrosis with adjacent gliosis or edema. Ferrocalcific deposits were prominent in the globus pallidus. The other sibling had similar changes in the brain at autopsy. This familial multisystem disorder especially involving the brain, skeletal muscle, and heart appears to represent a defect in some mitochondrial oxidative mechanism.
 ...
PMID:Familial poliodystrophy, mitochondrial myopathy, and lactate acidemia. 117 91

A 50-year old woman taking oral contraceptives (OC) for the past 3 years without side effects developed an aneurism of the jugular vein. A left thyroid lobectomy was performed and during thyroid exploration, organizing clots were dislodged and resulted in fatal pulmonary embolism. At autopsy, both main pulmonary arteries were plugged with organizing thrombi. A literature search failed to reveal a similar case. A definite relationship exists between OC use and thrombophlebitis. Vessey and Doll reported that a greater than eightfold-risk of thrombophlebitis exists among OC users as compared with nonusers of OC. 46 OC users had been known to develop thromboses in various vessels including cerebral; opthalmic; axillary, and deep leg veins (Luck and Bergin). Warning signals of impeding thrombosis include severe unilateral headache; transient blindness; and/or paresthesias and muscular weakness.
 ...
PMID:Internal jugular vein thrombosis with fatal iatrogenic pulmonary embolism: a case report. 118 59

Six hundred and forty-six patients with an eosinophilic pleocytosis were studied in Thailand over a 3-year period ending in March 1968. It was possible to segregate the cases into two clinical entities, which were termed typical eosinophilic meningitis and eosinophilic myeloencephalitis respectively. The clinical and laboratory finding of 484 cases of typical eosinophilic meningitis are reported here. The latter entity was generally benign and self-limited with a case mortality ratio of less than 0.5%. Acute severe headache was the most significant symptom. Fever was uncommon and abnormal neurologic findings were absent in 58% of cases. Sixteen percent of patients had visual impairment and 12% had an abnormal fundus. Impairment of the sensorium of a slowly progressive type and weakness of the extremities without localization were noted in 5% and less than 1% of patients, respectively. These signs occurred only in severely ill patients. Involvement of the cranial nerves was found in 17% of patients. Paralysis of the external rectus muscle of the eye and facial paralysis were found in 3% and 4%, respectively. The cerebrospinal fluid was characteristically turbid with a leucocyte count of more than 500 cells per mm3 in 75% of cases. It appeared that specific treatment of the disease was not indicated and that steroids and antibiotics did not have a definite beneficial effect on the course of the illness.
 ...
PMID:Eosinophilic meningitis in Thailand. Clinical studies of 484 typical cases probably caused by Angiostrongylus cantonensis. 120 Feb 57

Since Fincher reported a case with arteriovenous fistula between the external carotid artery and dural sinus, many type of cases have been reported. On the other hand, so called the external carotid avernous fistula has been recognized less 20 cases in literature. We have observed three additional cases of dural arteriovenous shunts in the region of the cavernous sinus. Case 1. A 52 year old woman had suffered from left side sever headache. There was weakness of the left extraocular muscles and left ptosis. A bruit was heard over the left orbit. She was treated for hypertension since 38 year old. And she has no history of recent trauma. Selective internal and external carotid angiographies showed the bilateral external carotid cavernous sinus fistula. No operative treatment was performed in this case and the symptomes disappeared with decrease of blood pressure. Case 2. A 50 year old man came to this clinic with chief complaints of right ptosis, diplopia and headache. He was treated for diabetes mellitus and hypertension for six month...
 ...
PMID:[Three cases of spontaneous bilateral external carotid-cavernous sinus fistula (dural arteriovenous shunts in the region of the cavernous sinus) (author's transl)]. 123 13


<< Previous 1 2 3 4 5 6 7 8 9 10 Next >>