Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0018681 (headache)
 56,091 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Family doctors identified psychological factors associated with the presenting complaint in 17% of children aged 7 to 12 years attending their care. When compared with other children attending within the same age group, children said by their doctors to show associated psychological factors tended to present with psychosomatic-type symptoms (bed-wetting, asthma, skin rashes, abdominal pains, blackouts and headaches) and to make more use of medical services (both hospital and primary care). Our findings suggest that the families from which these children came had relatively high surgery attendance rates and more mothers with health problems. More of these families were regarded by the doctors as being under stress, and there were indications that concern about the children and their schooling was particularly common amongst the parents. Exploration of parental concerns about their children's health and about educational expectations would appear specially indicated in these cases.
 ...
PMID:Psychosomatic aspects of children's consultations in primary care. 365 54

Epileptic discharges in the EEG record may be found in children not suffering from convulsive seizures. Such discharges often consist of spiking in the rolandic and midtemporal areas (labelled centrotemporal spikes) and less often in the occipital region. They may be multifocal. These focal discharges seem to be age-dependent, tending to disappear during the teenage years. Children displaying such discharges are discovered either through large-scale EEG studies of asymptomatic children or among those who are referred for EEG because of various nonrelated complaints such as headaches, bed-wetting, syncope, behaviour problems, and learning difficulties. Many of them are labelled as suffering from "masked epilepsy" and are considered as epileptics. One hundred such cases are reviewed, and the clinical and EEG data are analysed. Three illustrative case reports are presented, and the literature is critically reviewed. It is maintained that these children are not to be considered as epileptic and should not be treated with anticonvulsant drugs.
 ...
PMID:Focal epileptic EEG discharges in children not suffering from clinical epilepsy: etiology, clinical significance, and management. 679 52

The first series of children with obstructive sleep apnoea syndrome was reported in 1976. Later it became apparent that children may have breathing disorders during sleep without frank apnoea or 'hypopnoeas'. This pattern could be detected by measuring the oesophageal pressure. This led to the concept of sleep-disordered breathing as a spectrum that combines obstructive sleep apnoea syndrome and the upper airway resistance syndrome. Studies that do not take into account this spectrum may misclassify symptomatic patients as 'primary snorers'. The exact prevalence of sleep-disordered breathing in children is unknown but may be as high as 11%. There is a familial predisposition to sleep-disordered breathing. Nasal obstruction and mouth breathing influence facial growth, which may further lead to difficulty in breathing while asleep. Symptoms include an increase in total sleep time, nonspecific behavioural difficulties, hyperactivity, irritability, bed-wetting and morning headaches. Clinical signs include failure to thrive, increased respiratory effort with nasal flaring and suprasternal or intercostal retractions. Also, abnormal paradoxical inward motion of the chest may occur during sleep. Excessive daytime sleepiness and obesity are not always present. Untreated children may develop cardiovascular complications. The condition is treatable with continuous or bilevel positive airway pressure, and may be cured with surgery.
 ...
PMID:Sleep-disordered breathing in children. 978 33