Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0018681 (headache)
 56,091 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

For the assessing the incidence of mood disturbances among the neurological out-patients 3287 of them were examined by 111 neurologists during their routine practice. Early diagnosis, the type of mood disturbances and the depth of depression were estimated by the use of Beck's Depression Inventory, the questionnaire based on The Mini-International Neuropsychiatric Interview and Hamilton Depression Rating Scale, as well. Around half of the patients (50.47%) were suspected on depression, as an early diagnosis. In suspected and diagnosed depressive patients the symptoms as anxiety, low activity precordial pain, headaches, dry mouth, constipation, sleep and appetite troubles were significantly (p < 0.01) more frequent than in euthymic subjects. Among all studied patients the episode of depression were found as a final diagnose in 17.2%, recurrent depressive disorders--in 17.6% and dysthymia--in 2.8% of subjects. In finally diagnosed depressive patients the chronic neurological problems were significantly (p = 0.013) more frequent, as the cause of the visit, than in the euthymic ones. The low mood was equally frequent among the patients with Parkinson's disease, multiple sclerosis and cerebrovascular disorders, as well.
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PMID:[Prevalence of depression in neurological outpatients. DEPEND study]. 1291 Aug 52

Inappropriate sinus tachycardia (IST) is an uncommon form of arrhythmia which is characterized by an exaggerated increase in heart rate that is out of proportion to normal physiologic demands. Usually, IST is triggered by orthostasis, minimal exertion, and psychological stress. The etiology of IST remains ill-defined. However, proposed mechanisms include: enhanced sinus node automaticity, alterations in autonomic function associated with increased sympathetic activity or reduced parasympathetic activity, and impaired baroreflex control. Recently, increased levels of autoantibodies to beta-adrenergic receptors have been observed in patients with IST. The clinical presentation of IST is highly varied and ranges from short episodes of palpitations associated with dyspnea, atypical precordial pain, cephalalgia, fatigue, and occasional syncope and presyncope to incapacitating incessant tachycardia. In general, IST is a diagnosis of exclusion. It is important that other causes of sinus tachycardia are excluded before making a diagnosis. Evaluation of autonomic function is essential for a diagnosis of IST. Treatment of IST is based on autonomic function findings and involves multidisciplinary management, including cardiac rehabilitation. Control and restitution of normal autonomic function is essential. The prognosis is benign though regular follow-up is required to optimize therapy.
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PMID:[Inappropriate sinus tachycardia: an update]. 1809 89

The typical symptoms of pheochromocytoma are palpitations, sweating, headaches and hypertension. We report a 70-year-old female admitted to the hospital due to a sudden onset of precordial pain with electrocardiographic changes. After admission the patient evolved with recurrent chest pain accompanied by hypertensive paroxysms and a pheochromocytoma was suspected. Measurement of catecholamines and metanephrines confirmed the diagnosis and an abdominal magnetic resonance localized the tumor. The patient underwent surgery with successful removal of the pheochromocytoma and was discharged in good conditions.
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PMID:[Presentation of a pheochromocytoma as an acute coronary syndrome: report of one case]. 2495 15