Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0018681 (headache)
 56,091 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We report a case of a 66-year-old male with diffuse infiltration of neoplasm from the paranasal sinuses to the orbit and left cerebral hemisphere, associated with prominent edema. Initial complaints were headache and swelling of the forehead, which were followed by progressive symptoms, such as epistaxis, dacryops, and severe pains. Neuroimaging showed marked invasion of a neoplasm from the left paranasal sinuses into the intracranial space and to the frontal skull. Radical removal of the neoplasm and left orbital content with reconstruction of the anterior skull base using musculocutaneous flap was carried out by a multidisciplinary team. The pathological diagnosis was "poorly differentiated carcinoma from the paranasal sinus". Postoperatively the patient received radiation and chemotherapy. He is still alive with mild right hemiparesis and mild dysphasia, more than 2 years after surgery.
 ...
PMID:[A case of sinonasal carcinoma with intracranial invasion treated by a multidisciplinary team]. 1283 78