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Query: UMLS:C0018681 (headache)
 56,091 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Compared self-concepts of three groups, medical patients, chronic low back pain patients and chronic head pain patients (N = 60) to determine (1) whether chronic pain patients have self-perceptions that differ from other medical patients; (2) whether changes in self-perception are limited to physical attributes and capacities; and finally (3) whether persons who suffer different types of chronic pain would have differing self-concepts. Significantly lower self-concepts were obtained from groups of head pain and low back pain patients. Self-concept patterns for the two pain groups were quite similar with the exception of two self-concept components that were significantly lower for the head pain group. Differences were explained in terms of loss of many normal functions and disruption of normal life-styles. Implications for treatment of pain patients and for training of health professionals were discussed.
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PMID:The impact of chronic pain on the self-concept. 15 2

As an alternative to the conventional peripheral (vascular or chemical) thesis, the possibility of the central origin of pain in essential headaches is illustrated. In fact, observations carried out on animal and man reveal that, central pain, besides being organic, may be of a functional nature. It may be correlated to the lack of those biochemical mechanisms, which take place in the assimilation of those painful inputs at a cerebral level. Particularly pain may be caused by a lack of the 5HT turn-over. As a result of experiments carried out on animals, this takes the role of mediating pain inhibition, being present in the modulation stage of those multi-integrated processes which permit the central perception of pain. Some biochemical and pharmacological clinical observations suggest a serotonin lack in patients affected by essential headaches. A special interest is established by the reciprocal involvement of ancestral functions in essential headaches, such as: emotion, sleep, appetite, vomit, thermoregulation and sex, which are functions directly or undirectly controlled by serotonin. In the therapeutic field, the apparent contradiction between the benefit achieved by anti-serotonin drugs (such as: ergotamine, methisergide, org. G.C. 94 and LSD-25 at non-hallucinogen doses) and the substances with pro-serotonin activity (L-triptophane and L-5 hydroxy-triptophane) supports the hypothesis of a central lack of 5HT, due to the fact that the recent experiments on animal and man have shown a serotonin compatibility by "antiserotonin" drugs, when they are administered at therapeutic doses. If this initial thesis finds further confirmations, we could define essential headaches as a peculiar "pain disease", thus allowing them a well defined nosologic classification.
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PMID:[The central or peripheral nature of pain in essential headaches]. 18 Apr 58

Twenty volunteers were inoculated with various doses of human serum containing Phlebotomus fever virus (Sicilian type) to determine their clinical and serologic responses as well as the human infectious dose50 of the virus. All infected subjects developed fever which varied in duration from 6 to 74 hours. The most common symptoms during sandfly fever were headache, anorexia, myalgia, photophobia, low back and retro-orbital pain. Infected individuals developed a marked leukopenia characterized by an initial lymphopenia followed by protracted neutropenia. Little complement fixing antibody was detected in convalescent sera but most subjects developed significant rises in hemagglutination inhibiting antibodies. All infected subjects developed specific neutralizing antibodies with titers ranging from 1:40 to 1:2,560. Of the three serologic tests performed, the plaque reduction neutralization method appears to be the most sensitive test for detecting antibodies to Phlebotomus fever viruses.
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PMID:Clinical and serologic responses of volunteers infected with phlebotomus fever virus (Sicilian type). 18 Aug 44

The efficacy and side effects of a new synthetic compound, 16-phenoxy-W-17, 18, 19, 20-tetranor prostaglandin E2 methylsulfonylamide, for menstrual induction. The study was conducted in an outpatient clinic in 240 patients with a delay in menstruation of 6-14 days. In 206 patients (86%) the immunologic pregnancy test was positive before prostaglandin administration. Most of the remaining 34 (14%) patients with a negative pregnancy test had symptoms suggestive of pregnancy. Whenever there was doubt that amenorrhea was due to reasons other than pregnancy, the patients were not treated with prostaglandins. The patients' age range was 16-32 years; the parity range was 0-6. The treatment was successful in 228 patients (95%), i.e., there was uterine bleeding after prostaglandin administration followed by a negative pregnancy test within 14 days. In 6 patients with failed treatment, there was uterine bleeding after prostaglandin administration lasting for 2-13 days but the pregnancy remained positive. Prostaglandin failed to induce bleeding in 4 patients. In 3 of the patients the pregnancy test was positive before and 14 days after prostaglandin administration. The uterus was evacuated by vacuum aspiration in 9 patients. In 1 patient who had no uterine bleeding, pregnancy test was negative both before and 2 weeks after prostaglandin administration. 2 patients were admitted to the hospital the day after prostaglandin treatment for excessive bleeding. Curettage was carried out in both these patients and the bleeding stopped. 1 patient was readmitted to the hospital 8 hours after prostaglandin administration with severe pain in the lower abdominal region. On further examination a tubal pregnancy was diagnosed and confirmed by laparotomy. 2 patients were successfully treated for pelvic infection with antibiotics 7-10 days after prostaglandin administration. All patients experienced mild uterine pain a few minutes after prostaglandin administration. 16 patients required analgesics. The majority of the patients described the bleeding as heavier and longer in duration than their normal menstrual period. The average length of bleeding was 7.3 days with a range of 2-13 days. Side effects included 1 or 2 episodes of vomiting in 13 patients and headache in 9 patients.
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PMID:Termination of early pregnancy (menstrual induction) with 16-phenoxy-omega-tetranor PGE2 methylsulfonylamide. 20 Apr

Tiapridal a new molecule of the benzamide family, raises the pain-threshold level in the mesolimbic system. It has been shown to be effective in 66% of cases of headaches and pain resistant to therapy, and 75% of patients with nausea and vomiting associated with headaches. The average dosage is between 150 and 300 mg or day (1/2 to 1 tablet, 3 times a day). The product is extremely well-tolerated. Somnolence, the most frequent side-effect was noted in 17% of cases. Because of its excellent tolerance it can be prescribed in debilitated patients, alcoholics, and the elderly.
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PMID:[Prescribing tiapridal for headache and other painful conditions]. 21 5

Paget's disease usually is found in patients past the age of 40. Early presenting symptoms include headache, deafness, tinnitus, and pain due to radicular compression. The diagnosis is confirmed by radiographic features and elevated levels of serum alkaline phosphatase and urinary hydroxyproline. Bony overgrowth results in pressure on nearby soft tissues such as the brain, spinal cord, and certain peripheral nerves. The abnormally soft quality of the calvarial bone permits distortion by the weight of the brain. Dorsal inclination of the plane of the foramen magnum and the projection of the odontoid process into the posterior fossa lead to stretching of the brain stem over the odontoid process and the ventral margin of the foramen. Obstructive hydrocephalus may result. Sarcoma of the crainial vault may develop in cases of Paget's disease. Once cervicomedullary or spinal compression has occurred, surgical decompression may be necessary. Three drugs--calcitonin, disodium etidronate, and mithramycin--have been used with some benefit in the treatment of Paget's disease.
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PMID:Paget's disease and the nervous system. 21 14

Certain pain disorders may be difficult to diagnose because their presenting symptoms are confusing and difficult to classify, or because they occur so infrequently that they are not commonly considered. This article has presented a classification and discussion of selected pain states which the practitioner may find difficult to diagnose. When faced with a perplexing pain problem, the dentist is encouraged to perform a careful evaluation to determine whether the patient's pain is or is not of dental origin. Certain pain states require that the patient be referred for evaluation to other dental or medical specialists. The value of local anesthesia as a diagnostic aid in evaluating face and head pain has been presented.
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PMID:Selected pain states and the use of anesthesia in dentistry. 27 26

A sample of students (739) were questioned and examined for symptoms and signs associated with mandibular dysfunction. The most frequently mentioned symptoms were headache, TMJ sounds, and pain in the face or neck. No significant differences were found between men and women with symptoms other than headache. The most common dysfunctional signs were dull occlusal sounds on repeated, firm closure of the teeth, tenderness of muscles in the jaw or head, and sounds on condylar movement. Women had a higher prevalence of these signs. Subjects who were aware of bruxism (7.9%) were more likely to have tenderness of the masseter muscle and limited mouth opening. Limited mouth opening was associated with dull occlusal sounds, pain on opening the mouth, and sounds in TMJs. Headaches were associated with tenderness in muscles and joints. Subclinical signs associated with dysfunction occurred more frequently than did awareness of symptoms.
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PMID:Prevalence of mandibular dysfunction in young adults. 28 42

The cerebrovascular concomitants of migraine, initial vasoconstrictriction succeeded by vasodilatation, have long been considered the primary event in the pathogenesis of headache. In recent years, certain physicochemical concomitants of the attack have been identified, all involving blood platelets: these include hyperaggregability, decrease 5-hydroxytryptamine concentration and decreased monoamine oxidase activity. These changes may represent the response to a circulating humoral agent, deriving perhaps from the pulmonary vascular bed. The agent may not only bring about nonspecific damage of the kind described but be responsible for the cerebrovascular changes and stimulation of pain receptors characteristic of the disease. This circulating humoral agent may belong to the prostaglandin family.
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PMID:Cerebrovascular changes in migraine: secondary manifestations of a circulating humoral agent? 29 Jul 40

Interviews on the occurrence of Myofascial Pain-Dysfunction (MPD) Syndrome were held with a group consisting of 246 individuals 25 years of age. Every fifth interviewee said she/he had experienced clicking/crepitation from the TMJs. Five percent had felt pain when opening the mouth wide and 3% while chewing, yawning or talking. These frequencies of symptoms were much like those found in a probability sample of the total adult population in Norway and a probability sample of elderly Norweigians. In the present study, 28% said they had some or much headache recently. These symptoms varied with background characteristics, especially with sex. There was also a relationship between headache and MPD-symptoms. By combining the effect of the variables sex and headache upon the frequency of reported clicking/crepitation, it was tripled.
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PMID:Frequency and distribution of myofascial pain-dysfunction syndrome in a population of 25-year-olds. 29 21


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