Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0018681 (
headache
)
56,091
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
A 46-year-old extremely obese black woman presented with
headaches
, blurred vision, and visual obscurations. Her exam was notable for bilateral severe papilledema, retinal hemorrhages, and lethargy. Her CAT scan was normal, and a spinal tap revealed a very high opening pressure. Although this patient's presentation mimicked pseudotumor cerebri, the lethargy and retinal hemorrhages were atypical. Her hospital evaluation was notable for elevation of the serum bicarbonate level, and she was subsequently found to have hypoxia and hypercapnia on a blood gas. The patient was diagnosed as Pickwickian syndrome, with
obstructive sleep apnea
. Treatment of the pulmonary problem resulted in dramatic improvement in her eye findings and her lethargy, and optic nerve sheath fenestration was not necessary.
...
PMID:Disk edema in an overweight woman. 854 13
There has been no epidemiological study of snoring in Japan, and we therefore performed a questionnaire survey (in about 7,000 adult men working at a steel-making factory at the time of the yearly health examination, and investigated the relationship between the severity of snoring and 17 items including age, obesity, family history of snoring, daytime hypersomnolence, hypertension, smoking, alcohol intake and traffic accidents. We classified all the subjects into three groups, no snoring, mild snoring, and severe snoring group. We defined severe snorers as persons who snored loudly in both inspiratory and expiratory phases and those who snored loudly with apnea. We found that aging, obesity, smoking and alcohol intake are risk factors for snoring. Compared with non-snorers, severe snorers were found to have a high incidence of family history of snoring, daytime hypersomnolence, and history of treatment of hypertension. No relationship was found between the severity of snoring and the occurrence of automobile accidents. The proportion of severe snorers over 40 years old with obesity, daytime hypersomnolence and morning
headache
was 0.25%, representing the group that may have
obstructive sleep apnea
syndrome. The probable incidence of sleep apnea syndrome in men may be considerably lower in Japan compared with that in either U.S.A. or Europe.
...
PMID:[Epidemiological study of snoring--a questionnaire survey in factory workers]. 834 1
Obstructive sleep apnoea
(
OSA
) is characterized by abnormal breathing during sleep, and occurs when the upper airway is obstructed but respiratory effort continues. Causes of
OSA
include obesity, overindulgence in alcohol, and the use of sedatives. The patient complains of unrefreshed sleep, morning
headaches
and drowsiness, sometimes leading to depression and intellectual impairment. The treatment of choice is weight loss; however, the patient may also require mechanical nocturnal support to prevent the upper airway collapsing and causing
OSA
. A simple and effective non-surgical treatment for
OSA
is nasal continuous positive airway pressure.
...
PMID:Management of obstructive sleep apnoea. 837 59
We describe a 49-year-old man with chronic cluster
headache
unresponsive to all medications. Following investigation in the sleep lab he was found to have
obstructive sleep apnea
(
OSA
) with associated oxygen desaturations during rapid eye movement (REM) sleep. He awakened during one of these episodes with a typical
headache
. Treatment with nasal CPAP abolished his
OSA
and desaturations, and largely abolished his
headaches
. He then developed central apneas during REM sleep. Further treatment with BiPAP, with a set backup rate, abolished both the apneas and the
headaches
. We conclude that there may be a link between nocturnal cluster headaches and sleep apnea.
...
PMID:Nocturnal cluster headache associated with sleep apnea. A case report. 837 90
The success of Uvulopalatopharyngoplasty (UPPP) for
Obstructive Sleep Apnea
(
OSA
) can be assessed by a variety of parameters including clinical evaluation and polysomnography (PSG). Patients are often reluctant to undergo post-operative testing and insurance companies are often unwilling to reimburse for expensive overnight sleep studies. Due to the reality of these medical and economical problems, can a clinician be confident of the success of UPPP based solely on clinical evaluation? Sixty patients underwent UPPP for the treatment of
OSA
from July 1987 through June 1992. Patients treated with tracheostomy or other methods were not included in this study. Fifty-three patients (88%) reported an improvement in their symptoms of snoring, daytime somnolence, morning
headache
and apnea. Twenty-one patients (35%) had post-operative PSG. Eighteen of 21 patients (85%) reported improvement in their symptoms. Eleven of 21 patients (57%) showed objective improvement in their sleep apnea. The objective findings of PSG do not correlate, in a significant number of patients, with subjective clinical improvement of patients treated with UPPP.
...
PMID:Uvulopalatopharyngoplasty for obstructive sleep apnea in adults: clinical correlation with polysomnographic results. 844 31
This study investigates the relationship between nocturnal or morning
headache
and
obstructive sleep apnea
syndrome (sleep apnea). It is not known if
headache
of any type is more common in patients with sleep apnea than in other patients, but morning
headache
is a symptom of sleep apnea. A method is needed for identifying patients with chronic
headache
who might benefit from evaluation and treatment of sleep apnea. We performed a retrospective assessment of frequency of morning
headache
in patients grouped according to final diagnosis: sleep apnea (n = 72), periodic leg movements of sleep (n = 28), and psychophysiologic insomnia (n = 42). Prospective overnight sleep studies were obtained in a different group of 19 patients who presented for evaluation of
headache
. We selected certain patient characteristics as possibly indicative of sleep apnea-related
headache
. The retrospective study showed that 24% of patients with sleep apnea had frequent morning
headache
, which was not different from the other groups. In the separate group of 19 patients with chronic
headache
and suspected sleep disorder, 17 had sleep apnea. Nasal continuous positive airway pressure was prescribed to 14 patients. Marked improvement in
headache
occurred and persisted in 4 patients and moderate improvement in 3. Responders to therapy were more likely to have vascular headaches than mixed or tension headaches, more severe sleep apnea, and a nocturnal or morning timing to their
headaches
. However, there was large overlap in severity of sleep apnea and likelihood of response. We conclude that morning
headache
is not more common in sleep apnea than in other sleep disorders. However, over 30% of patients with chronic
headache
and other symptoms of sleep apnea have significant improvement in
headache
after treatment of sleep apnea.
Headache
PMID:Identification and treatment of sleep apnea in patients with chronic headache. 855 Mar 58
The relationship between
headaches
and sleep disturbances is complex and difficult to analyze. Both symptoms may have causal relations, or may be associated in the same patient with mutual reinforcements. We studied 25 patients presenting with morning or nocturnal
headaches
. Standard
headache
diagnosis and polysomnography were performed. After polysomnography, the diagnoses were reevaluated. The main
headache
entities were cluster, chronic paroxysmal hemicrania, migraine, tension, combined
headache
, and chronic substance abuse
headache
. For each group,
headache
, sleep data, and changes in diagnosis are discussed. The diagnosis was changed in 13 patients; the final diagnoses were periodic movements of sleep, fibromyalgia syndrome, and
obstructive sleep apnea
. The diagnoses of cluster
headache
and chronic paroxysmal hemicrania were not modified by polysomnography. The migraine and tension headache groups had a relative male preponderance, and the diagnosis was changed in approximately half of the patients. This was also observed in combined
headaches
. Patients who had chronic substance abuse
headaches
had mainly insomnia, which in some cases, was relieved by stopping medication. Data were also analyzed in terms of simple models linking
headache
and sleep disturbances. Such an approach allowed the identification of several modes of mutual interaction. In summary, morning or nocturnal
headaches
are frequent indicators of a sleep disturbance and their presence might justify polysomnography, and the use of simple clinical models may be useful for understanding the complex relationship between
headache
and sleep.
Headache
PMID:The relationship between headaches and sleep disturbances. 855 Mar 59
Forms of sleep apnea syndrome: Interrupted breathing and hypoventilation during sleep lead to sleep disorders and to cardiovascular sequelae. In the common
obstructive sleep apnea
syndrome (OSAS) apneas are related to intermittent obstruction of the upper airways. In the rarer central sleep apnea syndrome certain cardiovascular or central nervous system disorders lead to disturbed regulation of respiration connected with periodic breathing. Signs indicating OSAS: Loud, cyclic snoring, interrupted by cessation of breathing during sleep observed by relatives and excessive daytime to diurnal sleepiness indicate OSAS. Furthermore alteration of personality,
headache
in the morning, non-refreshing sleep and nocturnal choking sensations may indicate OSAS. When is evaluation necessary? Patients with complaints possibly induced by OSAS should be further evaluated since nocturnal application of continuous positive airway pressure (CPAP) by means of a nose mask and other treatment forms often lead to significant improvement of OSAS. In addition patients with untreated OSAS have an increased risk for car accidents and premature death as consequence of cardiovascular diseases. The type and extent of a supposed respiratory disorder is evaluated by means of a sleep study.
...
PMID:[Indications in sleep-apnea syndrome. When and why is further assessment meaningful?]. 919 Jun 46
The aim of this article is to present scientific and clinical evidence to support the role of proper head and neck posture in the management of snoring and
obstructive sleep apnea
. Obstruction of the upper-airway during sleep is a serious medical condition often associated with severe daytime somnolence, morning
headache
, and a host of cardiopulmonary complications, including but not limited to systemic and pulmonary hypertension, nocturnal cardiac dysrhythmias, myocardial infarction, and stroke. Though anti-snoring pillows are occasionally mentioned in the literature, the role of proper head-neck support during sleep has been largely neglected. In this article the effect of head-neck position on upper-airway obstruction during sleep is discussed from the perspective of both causation and treatment. Based on the evidence presented by the author, it is recommended that the use of cervical-support pillows be considered as an adjunctive treatment modality in patients suffering from snoring and
obstructive sleep apnea
.
...
PMID:Snoring and obstructive sleep apnea: does head posture play a role? 958 90
Obstructive sleep apnea
(
OSA
) syndrome occurs in 4% to 9% of middle-aged men and in 1% to 2% of middle-aged women. The incidence of
OSA
among morbidly obese patients is 12- to 30-fold higher. The pathophysiology of
OSA
is complex and incompletely understood. The important clinical symptoms of
OSA
include snoring, daytime sleepiness, restless sleep, morning fatigue, and
headaches
. The diagnosis is made by polysomnography. The possible sequelae of
OSA
are hypertension, left and right ventricular hypertrophy, sudden cardiovascular death, and increased risk for brain infarction. Nasal continuous positive airway pressure (nCPAP) appears to be the recommended treatment for
OSA
. Morbidly obese patients may also benefit from weight reduction gastric surgery.
...
PMID:Obstructive sleep apnea in the obese. 971 28
<< Previous
1
2
3
4
5
6
7
8
9
10
Next >>