Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0018681 (headache)
56,091 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Three groups of patients were studied: Group A consisted of 12 patients with cluster headache that was treated with lithium carbonate. Group B consisted of six patients with cluster headache that was managed with other drugs. Group C consisted of five patients with muscle contraction headache who received lithium. Serum lithium levels, platelet count, platelet serotonin levels, and platelet-rich plasma histamine levels were determined before and during therapy. The frequency of the headache and levels of serotonin and histamine tended to follow a parallel course in groups A and B: as the headache frequency dropped, serotonin and histamine levels fell. The stable period was characterized by little change in serotonin and histamine levels. Recurrences of headaches were accompanied by a return of serotonin and histamine to pretreatment levels. The course of cluster headache is related to changes in serotonin and histamine levels. Lithium, by modifying the headache course, changes serotonin and histamine levels.
...
PMID:Lithium carbonate therapy for cluster headache. Changes in number of platelets, and serotonin and histamine levels. 741 56

Tension-type headache is the term designated by the International Headache Society to describe what was previously called tension headache, muscle contraction headache, psychomyogenic headache, stress headache, ordinary headache, and psychogenic headache. The International Headache Society defines tension-type headache more precisely, distinguishes between the episodic and the chronic varieties, and divides them into two groups, those associated with a disorder of the pericranial muscles and those not associated with this type of disorder. Most clinic-based studies of tension-type headache suffer from selection bias, as they include patients with more severe headaches, patients with concomitant migraine, and patients with chronic daily headache. Traditionally, episodic tension-type headache and migraine have been considered distinct disorders, and the International Headache Society continues the separation. Some believe that both migraine and tension-type headache are recurring benign headaches. Chronic tension-type headache used to be called chronic daily headache, but they are not identical. Chronic tension-type headache must be distinguished from chronic daily headache even though the International Headache Society has not done this. Chronic daily headache is a syndrome consisting of a group of disorders and can be subclassified into primary and secondary types. The primary chronic daily headache disorders include transformed migraine, chronic tension-type headache, new daily persistent headache, and hemicrania continua. Secondary causes of chronic daily headache include post-traumatic headache, cervical spine disorders, and headache associated with vascular disorders and nonvascular intracranial disorders. Patients with frequent headaches are prone to overuse analgesics, ergotamine, or both. Most patients with chronic daily headache overuse symptomatic medication.(ABSTRACT TRUNCATED AT 250 WORDS)
Headache 1994 Sep
PMID:Tension-type headaches. 796 Jul 25

Muscle contraction headache (tension-type headache; MCH) usually begins when a patient is looking down or bending their neck. In the case of MCH patients, EMG activity of the posterior neck muscles at a sitting posture is significantly higher than the controls when the orbito-meatal line is horizontal or bending downward. Comparing with the controls, blood flow of the posterior neck muscle decreases sharply when the head is bent downward. Decrease of the muscle blood flow continues if the muscle is passively contracted. However, in the case of active contraction, blood flow recovers reflexly in 30 seconds. This explains why postural muscle contraction is important. When a patient is ordered to bend her neck down at the orbitomeatal line 30 degrees from horizontal, patient complains of a dull feeling at her posterior neck muscles in 30 seconds. In two minutes dull headache appears at the occipital area, soon becoming more intense and spreading to the forehead and temporal area. Once she looks up, muscle contraction of the neck disappears though she still feels headache. After the local anesthesia is applied to the occipital tender point, her headache disappears completely. From this experiment, MCH is a referred pain from occipital tender point which is the insertion point of occipital neck muscles. Patients with poor stability of cervical bone, and relatively heavy head weight compared with their neck are susceptible to MCH. Psychological stress decreases blood flow of the muscle and aggravates ischemic muscle contraction. Other risk factors include hypotension, anemia, and weak muscle power.
...
PMID:[Tension type headache with special reference to muscle abnormality]. 875 91

Twenty patients with diagnosis of muscle contraction headache were treated for pain relief in a physical therapy clinic once a week for six visits. The previous 3-week period of no treatment served as a control period during which patients recorded by diary their headache frequency, duration, and intensity using a numeric pain scale. Activity level, as measured by the Sickness Impact Profile, and verbal reports of headache frequency, duration, and intensity were recorded at four points during a 1-year period. Measurements were recorded at precontrol, pretreatment, posttreatment, and 12-month follow-up. Treatment included education for posture at home and work place, isotonic home exercise, massage, and stretching to the cervical spine muscles. Results indicated frequency of headaches and Sickness Impact Profile scores were significantly improved (P < 0.001) over the course of treatment. These benefits were maintained after 12 months.
Headache 1996 Mar
PMID:Effectiveness of a physical therapy regimen in the treatment of tension-type headache. 898 86

A single-dose, double-blind, randomized clinical trial was conducted to examine the relative analgesic effectiveness of 400 mg of ibuprofen (n = 153), 1,000 mg of acetaminophen (n = 151), and placebo (n = 151) in volunteers with muscle contraction headache. At regular intervals during a 4-hour period, participants evaluated headache pain intensity on a 100-mm visual analog scale and headache pain relief on a six-category scale. Both active agents were significantly different from placebo at all time points and in reducing pain intensity and providing relief of headache overall. Similarly, ibuprofen at 400 mg differed significantly from acetaminophen at 1,000 mg on both rating scales. Participants receiving ibuprofen at 400 mg achieved complete relief of headache faster than those receiving acetaminophen at 1,000 mg or placebo, and more participants taking ibuprofen experienced complete relief of headache than those taking placebo or acetaminophen. Both ibuprofen at 400 mg and acetaminophen at 1,000 mg are efficacious analgesic agents for muscle contraction headache, and ibuprofen at 400 mg is significantly more effective than acetaminophen at 1,000 mg for treating this condition.
...
PMID:Nonprescription ibuprofen and acetaminophen in the treatment of tension-type headache. 901 68

Tension-type headache is now the term used to describe headaches that have previously been grouped under various ill-defined headings such as 'tension headache', 'stress headache' and 'muscle contraction headache'. Tension-type headaches are characterized by pain that is mild or moderate in severity, bilateral in distribution, pressing or tightening in quality, and unaccompanied by major systemic disturbance or neurological signs. While many people have mild, infrequent tension-type headaches which they do not regard as an illness, a minority have chronic and often daily symptoms. Here we review the management of tension-type headaches in adults.
...
PMID:Management of tension-type headache. 1069 10

This study was conducted to analyse the prevalence and features of headache in patients with SLE. 44 patients with SLE were reviewed retrospectively. The mean age of the patients was 43.8 +/- 11.5 years (r: 22-68), mean time of evolution of SLE was 11.8 +/- 9.0 years (r: 1-30). 28 patients (27 woman and 1 man) had clinical evidence of central nervous system involvement, 18 patients (40.9%) had headache; 6 (33.4%) being vascular, 3 (16.7%) migraine, 9 (50%) muscle contraction headache. In 4 patients headache started before the other signs or symptoms of SLE, in 8 patients headache appeared in the first year of the disease. In the patients with headache other manifestations of nervous system involvement were present very often. Most patients had more than one symptom or sign during the course of the illness. The results of our examination showed that headache is frequent in the course of SLE and probably it is connected with vascular lesion of the nervous system. We failed to find a relationship between headache and other manifestations of SLE and the treatment of SLE.
...
PMID:[Headache in systemic lupus erythematosus]. 1110 80

Headache alone rarely indicates a sinister underlying cause. However, if the red flags are flying -- that is, if the patient is over 30 years old when the first headache develops, has additional symptoms or signs or has a very acute onset, particularly involving vomiting, then suspicion should be raised (see table 4). Although migraine has a high impact on the sufferer and affects a large proportion of the population on a monthly basis, the problem of acute muscle contraction headache is far greater. Other forms of headache are actually uncommon in comparison to these two. However, chronic daily headache is the most common condition seen by the medical professional because of its impact on the patient's quality of life. The key to the management of this condition is the assessment of analgesic dependence including NSAIDs, and particularly the codeine-containing agents. These should be avoided while long-term aproached such as exercise and certain prophylactic agents are introduced. It is true to say that if a careful initial assessment is made leading to a correct diagnosis, then the chance of appropriate management is enormously increased. Patients undergoing the correct management should generally see a massive improvement in their quality of life. Headache can, therefore, be a very satisfying condition for the clinician to treat.
...
PMID:Casebook: headache. 1260 25

Most primary headaches are classified into a few categories, such as migraine or muscle contraction headache, and patients suffering from these headaches are common. On the other hand, other primary headaches are very rare. In this section entitled "Other primary headaches", eight headaches, including primary stabbing headache, primary cough headache, primary exertional headache, primary headache associated with sexual activity, hypnic headache, primary thunderclap headache, hemicrania continua, and new daily-persistent headache, are described. Some characteristics of other primary headaches are common in symptomatic headaches, such as subarachnoid hemorrhage or arterial dissection. Therefore, careful evaluations including neuroimaging are necessary to exclude organic diseases.
...
PMID:[Other primary headaches]. 1621 86

The study was designed to examine the relationship between self-reported intensity of headache and surface EMG. 98 patients, diagnosed by their neurologists with "muscle-contraction headaches" (tension-type headaches) were referred to evaluate their suitability for biofeedback therapy. At the time of examination, they were asked to rate their average headache intensity on a 10-point scale. Surface EMG data were collected to assess actual muscle contraction. Analysis indicated that among patients diagnosed with muscle contraction headache, there is a positive significant correlation between self-reported intensity of headache and actual muscle-contraction. The current data lend support to the hypothesis that the tension in the headaches currently described as "tension-type" may in fact refer to actual muscular tension or contraction.
...
PMID:Relationship between self-reported intensity of headache and magnitude of surface EMG. 1667 56


<< Previous 1 2 3 4 5 6 Next >>