Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0018681 (
headache
)
56,091
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Three groups of patients were studied: Group A consisted of 12 patients with cluster
headache
that was treated with lithium carbonate. Group B consisted of six patients with cluster
headache
that was managed with other drugs. Group C consisted of five patients with
muscle contraction headache
who received lithium. Serum lithium levels, platelet count, platelet serotonin levels, and platelet-rich plasma histamine levels were determined before and during therapy. The frequency of the
headache
and levels of serotonin and histamine tended to follow a parallel course in groups A and B: as the
headache
frequency dropped, serotonin and histamine levels fell. The stable period was characterized by little change in serotonin and histamine levels. Recurrences of
headaches
were accompanied by a return of serotonin and histamine to pretreatment levels. The course of cluster
headache
is related to changes in serotonin and histamine levels. Lithium, by modifying the
headache
course, changes serotonin and histamine levels.
...
PMID:Lithium carbonate therapy for cluster headache. Changes in number of platelets, and serotonin and histamine levels. 741 56
Tension-type headache is the term designated by the International
Headache
Society to describe what was previously called tension headache,
muscle contraction headache
, psychomyogenic
headache
, stress
headache
, ordinary
headache
, and psychogenic
headache
. The International
Headache
Society defines tension-type
headache
more precisely, distinguishes between the episodic and the chronic varieties, and divides them into two groups, those associated with a disorder of the pericranial muscles and those not associated with this type of disorder. Most clinic-based studies of tension-type
headache
suffer from selection bias, as they include patients with more severe
headaches
, patients with concomitant migraine, and patients with chronic daily
headache
. Traditionally, episodic tension-type
headache
and migraine have been considered distinct disorders, and the International
Headache
Society continues the separation. Some believe that both migraine and tension-type
headache
are recurring benign
headaches
. Chronic tension-type headache used to be called chronic daily
headache
, but they are not identical. Chronic tension-type headache must be distinguished from chronic daily
headache
even though the International
Headache
Society has not done this. Chronic daily
headache
is a syndrome consisting of a group of disorders and can be subclassified into primary and secondary types. The primary chronic daily
headache
disorders include transformed migraine, chronic tension-type
headache
, new daily persistent
headache
, and hemicrania continua. Secondary causes of chronic daily
headache
include post-traumatic
headache
, cervical spine disorders, and
headache
associated with vascular disorders and nonvascular intracranial disorders. Patients with frequent
headaches
are prone to overuse analgesics, ergotamine, or both. Most patients with chronic daily
headache
overuse symptomatic medication.(ABSTRACT TRUNCATED AT 250 WORDS)
Headache
1994 Sep
PMID:Tension-type headaches. 796 Jul 25
Muscle contraction headache
(tension-type
headache
; MCH) usually begins when a patient is looking down or bending their neck. In the case of MCH patients, EMG activity of the posterior neck muscles at a sitting posture is significantly higher than the controls when the orbito-meatal line is horizontal or bending downward. Comparing with the controls, blood flow of the posterior neck muscle decreases sharply when the head is bent downward. Decrease of the muscle blood flow continues if the muscle is passively contracted. However, in the case of active contraction, blood flow recovers reflexly in 30 seconds. This explains why postural muscle contraction is important. When a patient is ordered to bend her neck down at the orbitomeatal line 30 degrees from horizontal, patient complains of a dull feeling at her posterior neck muscles in 30 seconds. In two minutes dull
headache
appears at the occipital area, soon becoming more intense and spreading to the forehead and temporal area. Once she looks up, muscle contraction of the neck disappears though she still feels
headache
. After the local anesthesia is applied to the occipital tender point, her
headache
disappears completely. From this experiment, MCH is a referred pain from occipital tender point which is the insertion point of occipital neck muscles. Patients with poor stability of cervical bone, and relatively heavy head weight compared with their neck are susceptible to MCH. Psychological stress decreases blood flow of the muscle and aggravates ischemic muscle contraction. Other risk factors include hypotension, anemia, and weak muscle power.
...
PMID:[Tension type headache with special reference to muscle abnormality]. 875 91
Twenty patients with diagnosis of
muscle contraction headache
were treated for pain relief in a physical therapy clinic once a week for six visits. The previous 3-week period of no treatment served as a control period during which patients recorded by diary their
headache
frequency, duration, and intensity using a numeric pain scale. Activity level, as measured by the Sickness Impact Profile, and verbal reports of
headache
frequency, duration, and intensity were recorded at four points during a 1-year period. Measurements were recorded at precontrol, pretreatment, posttreatment, and 12-month follow-up. Treatment included education for posture at home and work place, isotonic home exercise, massage, and stretching to the cervical spine muscles. Results indicated frequency of
headaches
and Sickness Impact Profile scores were significantly improved (P < 0.001) over the course of treatment. These benefits were maintained after 12 months.
Headache
1996 Mar
PMID:Effectiveness of a physical therapy regimen in the treatment of tension-type headache. 898 86
A single-dose, double-blind, randomized clinical trial was conducted to examine the relative analgesic effectiveness of 400 mg of ibuprofen (n = 153), 1,000 mg of acetaminophen (n = 151), and placebo (n = 151) in volunteers with
muscle contraction headache
. At regular intervals during a 4-hour period, participants evaluated
headache
pain intensity on a 100-mm visual analog scale and
headache
pain relief on a six-category scale. Both active agents were significantly different from placebo at all time points and in reducing pain intensity and providing relief of
headache
overall. Similarly, ibuprofen at 400 mg differed significantly from acetaminophen at 1,000 mg on both rating scales. Participants receiving ibuprofen at 400 mg achieved complete relief of
headache
faster than those receiving acetaminophen at 1,000 mg or placebo, and more participants taking ibuprofen experienced complete relief of
headache
than those taking placebo or acetaminophen. Both ibuprofen at 400 mg and acetaminophen at 1,000 mg are efficacious analgesic agents for
muscle contraction headache
, and ibuprofen at 400 mg is significantly more effective than acetaminophen at 1,000 mg for treating this condition.
...
PMID:Nonprescription ibuprofen and acetaminophen in the treatment of tension-type headache. 901 68
Tension-type headache is now the term used to describe
headaches
that have previously been grouped under various ill-defined headings such as 'tension headache', 'stress
headache
' and '
muscle contraction headache
'. Tension-type
headaches
are characterized by pain that is mild or moderate in severity, bilateral in distribution, pressing or tightening in quality, and unaccompanied by major systemic disturbance or neurological signs. While many people have mild, infrequent tension-type
headaches
which they do not regard as an illness, a minority have chronic and often daily symptoms. Here we review the management of tension-type
headaches
in adults.
...
PMID:Management of tension-type headache. 1069 10
This study was conducted to analyse the prevalence and features of
headache
in patients with SLE. 44 patients with SLE were reviewed retrospectively. The mean age of the patients was 43.8 +/- 11.5 years (r: 22-68), mean time of evolution of SLE was 11.8 +/- 9.0 years (r: 1-30). 28 patients (27 woman and 1 man) had clinical evidence of central nervous system involvement, 18 patients (40.9%) had
headache
; 6 (33.4%) being vascular, 3 (16.7%) migraine, 9 (50%)
muscle contraction headache
. In 4 patients
headache
started before the other signs or symptoms of SLE, in 8 patients
headache
appeared in the first year of the disease. In the patients with
headache
other manifestations of nervous system involvement were present very often. Most patients had more than one symptom or sign during the course of the illness. The results of our examination showed that
headache
is frequent in the course of SLE and probably it is connected with vascular lesion of the nervous system. We failed to find a relationship between
headache
and other manifestations of SLE and the treatment of SLE.
...
PMID:[Headache in systemic lupus erythematosus]. 1110 80
Headache
alone rarely indicates a sinister underlying cause. However, if the red flags are flying -- that is, if the patient is over 30 years old when the first
headache
develops, has additional symptoms or signs or has a very acute onset, particularly involving vomiting, then suspicion should be raised (see table 4). Although migraine has a high impact on the sufferer and affects a large proportion of the population on a monthly basis, the problem of acute
muscle contraction headache
is far greater. Other forms of
headache
are actually uncommon in comparison to these two. However, chronic daily
headache
is the most common condition seen by the medical professional because of its impact on the patient's quality of life. The key to the management of this condition is the assessment of analgesic dependence including NSAIDs, and particularly the codeine-containing agents. These should be avoided while long-term aproached such as exercise and certain prophylactic agents are introduced. It is true to say that if a careful initial assessment is made leading to a correct diagnosis, then the chance of appropriate management is enormously increased. Patients undergoing the correct management should generally see a massive improvement in their quality of life.
Headache
can, therefore, be a very satisfying condition for the clinician to treat.
...
PMID:Casebook: headache. 1260 25
Most primary
headaches
are classified into a few categories, such as migraine or
muscle contraction headache
, and patients suffering from these
headaches
are common. On the other hand, other primary
headaches
are very rare. In this section entitled "Other primary headaches", eight
headaches
, including primary stabbing
headache
, primary cough
headache
, primary exertional
headache
, primary
headache
associated with sexual activity, hypnic
headache
, primary thunderclap
headache
, hemicrania continua, and new daily-persistent
headache
, are described. Some characteristics of other primary
headaches
are common in symptomatic
headaches
, such as subarachnoid hemorrhage or arterial dissection. Therefore, careful evaluations including neuroimaging are necessary to exclude organic diseases.
...
PMID:[Other primary headaches]. 1621 86
The study was designed to examine the relationship between self-reported intensity of
headache
and surface EMG. 98 patients, diagnosed by their neurologists with "muscle-contraction headaches" (tension-type
headaches
) were referred to evaluate their suitability for biofeedback therapy. At the time of examination, they were asked to rate their average
headache
intensity on a 10-point scale. Surface EMG data were collected to assess actual muscle contraction. Analysis indicated that among patients diagnosed with
muscle contraction headache
, there is a positive significant correlation between self-reported intensity of
headache
and actual muscle-contraction. The current data lend support to the hypothesis that the tension in the
headaches
currently described as "tension-type" may in fact refer to actual muscular tension or contraction.
...
PMID:Relationship between self-reported intensity of headache and magnitude of surface EMG. 1667 56
<< Previous
1
2
3
4
5
6
Next >>