Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0018681 (headache)
 56,091 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The author describes a case in which different types of headaches occurred in life. In childhood the patient had typical attacks of ophthalmic migraine, at the age of 45 years classical Horton's neuralgia developed lasting 5 months, occurring 3-4 times daily and 2-3 times in night time. The pains were intense, their location was always identical and their duration was 15-20 min. It seemed at the time of observation that they represented a form intermediate between that described by Ekbom and Olivarius and that reported by Sjaastad and Dale. After treatment with Indomethacin immediate improvement was obtained with disappearance of pains.
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PMID:[Chronic Horton's neuralgia treated successfully with indomethacin]. 95 89

Migraine is classified into four basic categories: common, classic, cluster, and complicated. Ocular migraine is a periodic loss of vision in one eye typically lasting 30 minutes or less. Ophthalmoplegia is a severe ipsilateral hemicranial headache that is preceded by aura of lightning flashes and expanding circles of light, accompanied by temporary ocular motor nerve palsies.
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PMID:Vision and migraine. 178 28

We determined by radioimmunoassay plasma melatonin levels on blood samples drawn at 11 p.m. in migraine patients and control subjects. Ninety-three cephalalgic outpatients (75 females, 18 males) were compared to a control group (24 females, 22 males) matched according to age. Patients were divided into subgroups presenting common migraine (n = 38); ophthalmic migraine (n = 12); and tension headache associated with ophthalmic or common migraine (n = 24), and associated depressive status (n = 19). Statistical analysis revealed a decrease in plasma melatonin levels for the entire migraine population, compared to the control one, and a heterogeneity in both controls and patients; this heterogeneity was found mainly in the depressive and tension headache subgroups. When the migraine population--from which the depressive patients were excluded--was divided into male and female subgroups, a decrease in plasma melatonin levels was observed only for the female subgroups. Results are discussed with reference to the role of the pineal gland in the synchronization of the organism with the environmental conditions.
Headache 1989 Apr
PMID:Nocturnal plasma melatonin levels in migraine: a preliminary report. 271 76

The efficacy of propranolol used for prophylactic treatment of 122 patients with migraine is evaluated. Of the 122 patients 51 were suffering from simple or ophthalmic migraine, 43 from vasomotor cephalgia, and 28 from cervical migraine. On the basis of the data obtained the authors come to a conclusion that propranolol is an effective remedy for prevention of migraine and other headaches. According to the authors' data the optimal daily dose of the drug is 120 ml, and the treatment is to be given for not less than 12 weeks. The drug is well tolerated, and the side effects are negligible.
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PMID:[Use of propranolol in the treatment of migraine]. 706 9

The number of patients with ophthalmic migraine is steadily increasing. The symptoms of their attacks are dominated by typical visual aura, followed by major or minor headache. The authors present the experience of three physicians who observed the symptoms on themselves. The first one has suffered from the disease already for fifty years, the second and third one 25 years each. In the discussion the authors deal with the differential diagnosis of the disease and its possible treatment.
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PMID:[Visual perceptions in ophthalmic migraine]. 962 50

There is no doubt that ocular migraine also known as retinal migraine or ophthalmic migraine should not to be confused with ophthalmoplegic migraine. The hallmark of ocular migraine is the unilateral visual loss or "monocular transient loss of vision" associated or followed by the headache. Better safe than sorry, therefore an ophthalmologic examination during the migraine attack is the most diagnostic method. age with typical history for ocular migraine. Importantly supportive data sustain that different neuro-ophthalmologic manifestations as amaurosis fugax, retinal vascular thrombosis and optic neuropathy, may be considered as the ocular hallmarks of the Hughes's syndrome. Clues for the evaluating of antiphospholipid antibodies include recurrent thrombosis especially in young people, recurrent fetal loss, and thrombocytopenia. There are no studies that focus exclusively on the prophylaxis of ocular migraine. Ocular features due to antiphospholipid antibodies - induced thrombosis or Hughes's syndrome should be treated with anticoagulant therapy.
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PMID:Ocular migraine and antiphospholipid antibodies--where we stand? 1806 48