Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0018681 (headache)
 56,091 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Inverted papilloma is a rare benign sinonasal tumor characterized by a potentially invasive nature. The lateral nasal wall represents the most common site of origin, whereas paranasal sinuses are frequently involved by extension. In contrast, primary sinus inverted papillomas have rarely been reported. The present study describes a 52-year-old man that presented with a one-year history of unilateral nasal obstruction, nasal discharge, epistaxis, occipital headache and decreased sense of smell. After nasal endoscopic examination, computed tomography was taken and endoscopic biopsy was performed which demonstrated isolated inverted papilloma of the left sphenoid sinus. Tumor was taken via transnasal endoscopic sphenoidotomy. No evidence for recurrent disease was seen after 12 months of follow-up and his symptoms were completely relieved. Endoscopic transnasal sphenoidotomy remains an effective treatment for these lesions.
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PMID:[Isolated inverted papilloma of the sphenoid sinus: a case report]. 1676 14

Inverted papilloma is a benign neoplasm of uncertain ethiology. The tumour is considered locally aggressive, its tendency to invade adjacent paranasal structures and high recurrence rate causes. In this work was described one case of 102 year's old patient with unilateral nasal obstruction since 5 month and headache. Endoscopy surgery was applied. Histological examination revealed inverted papilloma.
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PMID:[Endoscopic surgery in treatment of inverted papilloma nose et paranasal sinuses in the older patient]. 1766 11

Inverted papilloma of the nose is an uncommon, but, well document ed lesion of the mucosal lining of the nose and paranasal sinuses. The manifestation of this disease are usually unilateral nasal obstruction, mucopurulent nasal discharge, anosinia and occasional headache. It is very rare to she this condition presenting with dyspnoea and dysphagia due to its extension in the laryngopharynx. In this paper, we report a patient who presented to us with dyspnoea and dysphagia due to a huge papillomatous mass extending from right nasal cabity to the maxillary antrum laterally, posteriorly into the nasopharynx, interiorly into the oropharynx and the laryngopharynx.
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PMID:Inverted Papilloma - An Unusual Presentation (Foreign-Body like). 2311 81

Inverted papilloma (IP) is a benign uncommon epithelial tumor, arising mostly from the lateral nasal wall. Though benign, this lesion is highly invasive into surrounding tissues and malignant transformation may occur. Primary IP of the sphenoid sinus and intracranial extension with dural invasion, even without histological evidence of malignancy, has only rarely been described. Hypopituitarism as a complication of this lesion has never been reported. We describe the case of a 59-year-old woman who was evaluated because of a 5-year-history of severe headaches and abnormalities in the visual field. Magnetic resonance imaging (MRI) showed a 1.4 per 2.0 cm heterogeneous sellar lesion with suprasellar and sphenoid sinus extension, eroding the sellar floor with optic chiasm compression. Otolaryngologists gave her 16 mg/day of prednisone during approximately 3 months with a near total regression of the mass on MRI. The endocrine biochemical evaluation showed pituitary gonadal, thyroid and adrenal insufficiency. A new MRI showed growth of the tumor with obliteration of the sphenoid sinus. An endoscopic sinus biopsy revealed an IP, so a transnasal endoscopic sinus surgery was performed with complete resection evidenced by MRI a year later.
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PMID:[Pseudo-pituitary tumor and hypopituitarism secondary to a sphenoid sinus inverted papilloma]. 2415 8