Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0018681 (headache)
 56,091 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 22-year-old woman presented with a 3-year history of progressive frontal headache. Computerized tomography (CT) and magnetic resonance imaging (MRI) revealed a tumor in the left trigone of the lateral ventricle and which enhanced homogeneously. The tumor was attached to the cerebellar tentorium and was compressing the brain stem. On the angiography, no tumor staining was seen. On November 26, 1996, total removal of the tumor was performed using the left subtemporal approach. The tumor was attached to the cerebellar tentorium. The pathological diagnosis was mesenchymal chondrosarcoma. After surgery, gamma-knife radiosurgery was carried out on the tentorium at the place where the tumor had been attached. There has been no recurrence for 6 months. Mesenchymal chondrosarcoma in the brain is very rare and therapy for this tumor is difficult. We report this rare tumor and the therapy is discussed.
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PMID:[Intracranial mesenchymal chondrosarcoma arising from the cerebellar tentorium: case report]. 948 93

Intracranial Mesenchymal Chondrosarcoma is a very rare and uncommon entity that affects young adults. We came across one such patient who presented with severe headache and intermittent nausea and vomiting. The clinical, radiological preoperative diagnosis was a meningioma, on histological examination it turned out to be mesenchymal chondrosarcoma of tentorial region in posterior fossa, uncommon site for this entity.
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PMID:Intracranial extra-skeletal mesenchymal chondrosarcoma. 1697 25

Mesenchymal chondrosarcoma of the brain is one of the rarest tumors with dismal prognosis. A 26-year-old man presented with headache, vomiting, and diplopia. On evaluation, a moderately enhancing extra-axial lesion was seen in right temporal region involving right greater wing of sphenoid, adjacent right maxillary sinus, and lateral wall of right orbit. Patient underwent magnetic resonance imaging of the spine and computed tomography (CT) of the chest for possible metastasis which showed lesion in lumbar vertebrae and left lung. Patient was planned for CT-guided lung biopsy which proved inconclusive. The patient was further planned for craniotomy and underwent craniotomy with microscopic excision of the mass. Histoimmunochemistry was suggestive of extraskeletal mesenchymal chondrosarcoma. Mesenchymal chondrosarcoma of the brain is highly aggressive tumors which are difficult to differentiate radiologically. Radical excision followed by chemoradiotherapy is optimal treatment of choice.
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PMID:Mesenchymal Chondrosarcoma of the Brain with Metastasis: A Case Report with Literature Review. 3236 92