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Query: UMLS:C0018681 (headache)
 56,091 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

1 The absorption of effervescent aspirin was studied in two groups of patients during attacks of migraine. The first group received effervescent aspirin alone whilst the second group received intramuscular metoclopramide before effervescent aspirin. 2 After effervescent aspirin alone there was significant impairment in the rate of aspirin absorption during migraine attacks compared with the rate of aspirin absorption in normal volunteers and in the same patients when headache-free. 3 When metoclopramide was given before effervescent aspirin the rate of aspirin absorption during migraine attacks was not significantly different from that obtained in normal volunteers given effervescent aspirin alone or from that obtained in the patients themselves when given both metoclopramide and effervescent aspirin when headache-free. 4 It is concluded that the impairment of absorption of effervescent aspirin during migraine attacks is related to impaired gastro-intestinal motility with delayed gastric emptying and that this impaired motility can be overcome by parenteral metoclopramide.
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PMID:The effect of metoclopramide on the absorption of effervescent aspirin in migraine. 79 18

The incidence of a foramen retroarticulare atlantis in a group of 380 patients was investigated and put in relation to the frequency of headaches, migraine and Meniere's syndrome. These complaints are found more frequently in patients with a retroarticular foramen. Angiograms of the vertebral artery show vascular constrictions in the region of the foramen retroarticulare in the majority of patients examined. In 5 patients, the clinical symptoms of a mechanical irritation with changes in blood flow through the vertebral artery in the region of a foramen retroarticulare atlantis have been described.
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PMID:[Foramen retroarticulare atlantis and the vertebral angiogram (author's transl)]. 80 11

Headaches appear to be a reaction to changes in either exogenous or endogenous levels. We are now investigating serum immunoglobulins in women with menstrual migraine and have found that in 22 women, 6 have low immunoglobulin A levels, all below the normal range, and 5 have high immunoglobulin M levels, above the normal range. The hereditary aspect of migraine may depend on inheriting a particular immune pattern which might cause a special sensitivity to hormone effects on blood vessels. This might account for the suppression of menstrual migraine by cortisone or large doses of progesterone. Deficiency of progesterone is unlikely to be responsible for the premenstrual syndrome as the week following menstruation is usually the time which is most often free from symptoms and at this part of the cycle there are very low levels of progesterone. The most reactive women are also the most sensitive to the side effects of drugs or hormones given to treat migraine, which makes the treatment of migraine difficult.
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PMID:[The influence of hormones on headaches in women and the associated endometrial patterns (author's transl)]. 81 Jun 82

35 patients suffering from different painful conditions were treated with transcutaneous application of a slightly painful electrical stimulus. The effect was manifested in complete relief in six patients treated during an attack of migraine and in a relatively high number of other cases of headache with relief of pain. In some cases there was a long-lasting favourable effect for periods up to 8 months. For the theoretical explanation the 'gate control' theory is referred to. With respect to the practical application, the special indication in cases of chronic headache is emphasised, especially since this method avoids the risks of habit-formation or other damaging effects of drug therapy.
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PMID:[Transcutaneous nerve stimulation for the treatment of migraine and other head pain (author's transl)]. 81 29

The results of the study of the activity of platelet monoamine oxidase (MAO) in patients with migraine headaches or with 'cluster headaches' are presented. In both types of headaches, MAO activity is lower than in normal subjects. We suggest that the low MAO activity is due to a primary constitutional defect.
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PMID:A study of the activity of platelet monoamine oxidase in patients with migraine headaches or with 'cluster headaches'. 85 72

A REG study of 90 patients with migraine headaches demonstrated that a significant role in their genesis is played by regional hypertonia of cerebral vessels and phenomena of cerebral angiodystonia with a tendency towards spastic reactions rather than hypotonic. The use of stugeron for preventive treatment of migrain cephalgia was effective in 85 of the 100 treated patients and especially in those cases where there was an increased tone of the cerebral vessels according to the REG data. The most constant changes demonstrated by the REG were normalization of the vascular tone, more expressed in initial hypertone and to a less extent its influence on the cerebral blood flux (more frequently towards its increase and a decrease of hemispheric asymmetry). The authors consider it expedient to use REG methods when prescribing stugeron.
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PMID:[Rheoencephalographic findings in migrainous cephalalgia and their dynamics during treatment with stugeron]. 85 28

That migraine can present with a severe headache of sudden onset mimicking that of subarachnoid hemorrhage--the so-called "complicated migraine with meningeal manifestations" of Pearce and Foster--is not readily appreciated. Over the past three years, seven patients have been referred to us with a presumable diagnosis of subarachmoid hemorrage. In each one of these patients, the clinical features (an explosive headache, relapsing in three, and a normal neurological examination) together with appropriate laboratory investigations (cerebro-spinal fluid analysis, electroencephalography, echoencephalography, brain scan, arteriography, pneumoencephalography) have ruled out the diagnosis of subarachnoid hemorrhage, as well as less common causes of explosive headaches such as ball-valve tumors of the ventricular system, intra-cerebral hemorrhage, hemorrhage into a tumor. In three out of these seven patients, there was no history of migraine. Bening explosive headaches mimicking subarachnoid hemorrhage, occurring in patients with or without antecedents of migraine, are not as unusual as one might conclude from a review of the literature. Proper recognition of this syndrome is important since it might help to sort out those patients with explosive headaches who need not be submitted indiscriminately to risk-fraught procedures.
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PMID:[Headache simulating meningeal hemorrhage]. 86 64

This letter is in reply to a previous article of April 30 asking if oral contraceptives cause disease of the uterine arteries. The writer has found that changes in the small vessels of the endometrium are an early effect of taking oral contraceptives. Proliferation of endometrial arterioles has been related to headache and migraine incidence. Distended sinusoids have accompanied tiredness and dilated leg veins. Stromal condensation around sinusoids has been found with leg cramps. These changes have preceded thrombosis. It is thought that oral contraceptives cause generalized vascular overactivity. Symptoms are usually rapidly reversible on discontinuing the therapy. At an acute migraine clinic, oral contraceptives and smoking have been important contributing factors in patients requiring emergency treatment. Oral contraceptives are thought to be a more potent cause of bascular disease than smoking.
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PMID:Oral contraceptives and the uterine vessels. 87 84

4 cases of thrombosis of the intracranial venous sinuses (TIVS) which occurred in patients 22-38 years of age who used oral contraceptives are discussed. Of the 29 reported cases of this type, 19 of the patients died. There are 3 stages in the evloution of TIVS: headache, hemispheric focus symptoms (e.g., Bravis-Jacksonian crises), and a phase of dramatic aggravation (e.g., severe headache, coma). Arteriography of the carotid artery and cerebral scintigraphy are the methods used to diagnose TIVS. Besides such predisposing factors as diabetes, obesity, migraines, etc., the use of oral contraceptives containing estrogen seem to be a factor in the development of TIVS, particularly within the 1st year of estrogen use. The reduction of cerebral volume seems to be the best treatment for TIVS: anticoagulants and thrombolytic compounds can cause fatal hemorrhaging
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PMID:[Thrombosis of the intracranial venous sinuses after ingestion of estroprogestative agents. 4 cases]. 88 3

We describe seven patients with vascular headaches. Five of them had cluster headaches, which were preceded by migrainous scotamata (two patients), weakness contralateral to the pain (one), accompanied by ipsilateral photopsias (one), or by contralateral paresthesias (one). The other two patients had "clusters" of daily common migraine headaches separated by long free intervals. The symptoms of these patients suggest a common root for cluster and migraine headaches.
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PMID:The clinical link between migraine and cluster headaches. 88 78


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