Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0018681 (headache)
 56,091 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

5 to 8% of women on oral contraception (OC) suffer from headaches or migraines. There is, for the moment, no serious pathogenic explanation of this phenomenon. Blood pressure and eyesight problems should be checked. Headache can at times be the sign of serious cerebro-vascular accidents; in such cases OC should be stopped immediately.
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PMID:[Migraine or headache and oral contraceptives]. 44 97

Numerous factors, such as location of pain, sex, frequency and pattern of occurrence, and symptoms, distinguish cluster headache from migraine. Cluster headache is characterized by severe unilateral periorbital pain. Attacks lasting from several minutes to several hours occur many times a day over a period of weeks to months. Opinions differ as to whether cluster headache is a variant of migraine or a completely different disorder. For relatively mild attacks, abortive treatment with ergotamine tartrate is usually successful. Cases which do not respond to abortive measures require prophylaxis.
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PMID:Cluster headache: relation to and comparison with migraine. 45 Aug 31

A study of 46 patients has shown that Clonazepam is an effective drug in preventing attacks of pain in essential trigeminal and glossopharyngeal neuralgia and in Sluder's syndrome. The therapeutic action of the drug is less evident in different types of migraine, among which only the combined headache presents good results to the treatment. The effective dose of this drug is generally not greater than 3 mg/die and does not give rise to side effects in long-term prescription.
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PMID:[Clonazepam in painful syndromes of the head]. 45 5

Scintillating scotomas are frequently seen without an associated headache and in general should be considered a benign symptom. In this series of 10 patients with an age range from 25 to 72 years, there were 7 female and 3 male patients. With an average follow-up of 1 1/2 years there was no patient who subsequently developed migraine headaches or any persisting neurologic sequelae.
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PMID:The scintillating scotoma without headache. 45 55

Results of comprehensive neurological examinations of 4 patients suffering from periodic disease have shown that the latter may be not only a disease entity, but also a syndrome characterizing some organic affections of the brain. The abdominal and other crises of the periodic disease included cerebrovascular disturbances which manifested hemipareses, syncopes, and migraine-like cephalgia. EEG and REG examinations have revealed dysfunction of the mesodiencephalic structures which, probably, underlies the pathogenesis of the periodic disease. The knowledge of the formerly almost unexplored neurological manifestations of the periodic disease will contribute to improvement of the therapy of this rare ailment.
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PMID:[Neurologic manifestations of periodic disease]. 46 61

Twenty-four migraine patients were randomly assigned to one of four conditions: (a) self-monitoring of headache activity (waiting list), (b) frontalis EMG biofeedback, (c) digit temperature biofeedback, and (d) digit temperature biofeedback plus Rational-Emotive Therapy (RET). Bidirectional control over the target physiological response was assessed through a reversal design in each session. Following at least a four-week baseline, the three biofeedback groups received 8 to 10, 30-minute sessions of bidirectional biofeedback training, scheduled twice a week. Subjects in the combined digit temperature biofeedback plus RET group received three 40-minute sessions of RET as an addition to the third, fifth, and seventh biofeedback sessions. Records of daily home practice were kept throughout treatment and three-month followup. Subjects on the waiting list monitored headaches for at least five months, corresponding to "baseline", "treatment", and three-month followup. Digit temperature biofeedback alone and in conjunction with RET did not prove to be more effective than the control conditions. All the EMG subjects reduced headache activity to two-thirds or less of the baseline level by the third month of followup. Bidirectional digit temperature performance did not improve with training, was demonstrated in only 33% of the biofeedback sessions, was not maintained over time, and was unrelated to improvement in headache activity. EMG subjects reported biofeedback performance to be an easier task and met the performance criterion on 85% of the sessions. The frequency of home practice contributed over 55% of the variance in retrospective estimates of headache improvement but was not related to changes in daily records of headache activity.
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PMID:Biofeedback and rational-emotive therapy in the management of migraine headache. 46 45

This paper presents evidence for my hypothesis that the diverse features of a migraine attack, both during the prodromal and the headache phases, become explicable if migraine is caused by a primary abnormality of platelet behaviour. This hypothesis places migraine among the most common disorders of the blood.
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PMID:Migraine. A platelet hypothesis. 47 66

The aim of this work was to study digestive tract function by means of xylose test in patients with attacks of headaches. The investigations were carried out in 14 patients with migraine, 10 with Horton's headache and 1 patient with both these conditions. In patients with migraine or Horton's headache the xylose test was normal in 65% of cases, in the remaining 35% (8 patients, 4 in each group) xylose elimination was abnormal, because it was below 30%. The authors discuss the factors which could influence the abnormal results of xylose test in these patients, since they had no signs of other diseases than the mentioned headaches.
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PMID:[Xylose test in patients with attacks of headaches (migraine, Horton's headache)]. 48 87

The effect of the calcium antagonist, nifedipine, on menstrual pain was investigated in 40 women with severe, primary dysmenorrhoea and 36 of them were observed over 3 consecutive menstrual cycles. Twenty-six patients experienced good pain relief, 10 moderate relief and 4 reported no benefit. The frequency of symptoms associated with menstrual pain was not reduced. Fifteen women regularly suffering from migraine during the menstrual period reported increased headache after intake of the drug. Due to this side effect four of these patients did not continue treatment for more than one cycle. All patients had transient facial flushing occurring 15--30 min after drug intake; this was well tolerated. An increase in pulse rate was also invariably found. However, only 5 patients complained of palpitations. Twenty-five of the 36 women completing the three-month trial wanted to continue nifedipine therapy regularly. It is concluded that calcium antagonists like nifedipine can be used for treatment of severe primary dysmenorrhoea, and that further evaluations of these drugs are indicated.
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PMID:Trial of the calcium antagonist nifedipine in the treatment of primary dysmenorrhoea. 48 22

This is the common "tension" or "nervous" headache. It is extracranial in origin, and is often precipitated by anxiety or depression. The headache is usually bilateral, nonpulsatile and of longer duration than migraine, with no focal signs or symptoms. While aspirin remains the most practical and useful analgesic for head pain of low intensity, combination agents are useful and drugs to control anxiety associated with headache are appropriate.
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PMID:Muscle contraction headache. 49 93


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