Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0018681 (headache)
 56,091 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

OBJECTIVE Arachnoid cysts (ACs) are congenital lesions bordered by an arachnoid membrane. Researchers have postulated that individuals with an AC demonstrate a higher rate of structural brain injury after trauma. Given the potential neurological consequences of a structural brain injury requiring neurosurgical intervention, the authors sought to perform a systematic review of sport-related structural-brain injury associated with ACs with a corresponding quantitative analysis. METHODS Titles and abstracts were searched systematically across the following databases: PubMed, Embase, CINAHL, and PsycINFO. The review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Peer-reviewed case reports, case series, or observational studies that reported a structural brain injury due to a sport or recreational activity (hereafter referred to as sport-related) with an associated AC were included. Patients were excluded if they did not have an AC, suffered a concussion without structural brain injury, or sustained the injury during a non-sport-related activity (e.g., fall, motor vehicle collision). Descriptive statistical analysis and time to presentation data were summarized. Univariate logistic regression models to assess predictors of neurological deficit, open craniotomy, and cystoperitoneal shunt were completed. RESULTS After an initial search of 994 original articles, 52 studies were found that reported 65 cases of sport-related structural brain injury associated with an AC. The median age at presentation was 16 years (range 4-75 years). Headache was the most common presenting symptom (98%), followed by nausea and vomiting in 49%. Thirteen patients (21%) presented with a neurological deficit, most commonly hemiparesis. Open craniotomy was the most common form of treatment (49%). Bur holes and cyst fenestration were performed in 29 (45%) and 31 (48%) patients, respectively. Seven patients (11%) received a cystoperitoneal shunt. Four cases reported medical management only without any surgical intervention. No significant predictors were found for neurological deficit or open craniotomy. In the univariate model predicting the need for a cystoperitoneal shunt, the odds of receiving a shunt decreased as age increased (p = 0.004, OR 0.62 [95% CI 0.45-0.86]) and with male sex (p = 0.036, OR 0.15 [95% CI 0.03-0.88]). CONCLUSIONS This systematic review yielded 65 cases of sport-related structural brain injury associated with ACs. The majority of patients presented with chronic symptoms, and recovery was reported generally to be good. Although the review is subject to publication bias, the authors do not find at present that there is contraindication for patients with an AC to participate in sports, although parents and children should be counseled appropriately. Further studies are necessary to better evaluate AC characteristics that could pose a higher risk of adverse events after trauma.
...
PMID:Sport-related structural brain injury associated with arachnoid cysts: a systematic review and quantitative analysis. 2703 26

Arachnoid cysts are intracranial pathologies in the space between the pia mater and the dura mater of the brain and cerebellum. Arachnoid cysts are derived from the arachnoidea mater, which while yielding to germination or splitting creates a space filled with liquid with a composition similar to cerebrospinal fluid. The aim of the study is to present possible clinical symptoms and radiological presentation of intracranial arachnoid cysts. The symptoms of intracranial arachnoid cysts are dependent on its size and location. Small cysts are often asymptomatic, while reaching a large size they have the effect of weight, which can lead to oppression and displacement of neurovascular structures, increased intracranial pressure, and therefore such cysts may be the reason for the occurrence of neurological symptoms. Increasing headaches, dizziness, nausea with or without vomiting, stiff neck may even feign subarachnoid hemorrhage (SAH). In neuroimaging arachnoid cysts account for 1-2% of all intracranial pathologic masses. The most common location of arachnoid cysts is down the middle and rear of the skull in natural bodies of cerebrospinal fluid. Arachnoid cysts have a high rate of change. They can undergo spontaneous growth as well as the reduction or disappearance. Headaches, nausea or vomiting, worsening of mood, mental status changes, ataxia, seizures, hearing loss may be symptoms of serious intracranial pathology requiring diagnosis based on neuroimaging.
 ...
PMID:[Intracranial arachnoid cysts in the clinical and radiological aspect]. 2771 44

Arachnoid cysts are congenital, benign, non-neoplastic, extra-axial intra-arachnoidal lesions. Arachnoid cysts rarely become symptomatic, with bleeding. Intracranial haemorrhage as a complication of arachnoid cyst is a very rare condition. It is well-known that mid-cranial fossa cysts might cause intracerebral haemorrhage or subdural haematoma secondary to traumas. However, the occurrence of spontaneous subdural haematoma secondary to arachnoid cysts, developing without any trauma, is even rarer. A 17-year-old boy presenting with diplopia and headache, with no history of trauma, was diagnosed with left temporal lobe arachnoid cyst and left fronto-parietal subdural haematoma. He was operated on, solely for his haematoma, with no intervention performed for the arachnoid cyst. Authors suggest that it is sufficient to perform an operation for the haematoma only -without arachnoid cyst resection- if there is no clinical presentation specific to the arachnoid cyst itself.
 ...
PMID:Spontaneous Subdural Haematoma Developing Secondary to Arachnoid Cyst Rupture. 2789 97

Arachnoid cysts are intracranial pathologies in the space between the pia mater and the dura mater of the brain and cerebellum. Arachnoid cysts are derived from the arachnoidea mater, which while yielding to germination or splitting creates a space filled with liquid with a composition similar to cerebrospinal fluid. The aim of the study is to present possible clinical symptoms and radiological presentation of intracranial arachnoid cysts. The symptoms of intracranial arachnoid cysts are dependent on its size and location. Small cysts are often asymptomatic, while reaching a large size they have the effect of weight, which can lead to oppression and displacement of neurovascular structures, increased intracranial pressure, and therefore such cysts may be the reason for the occurrence of neurological symptoms. Increasing headaches, dizziness, nausea with or without vomiting, stiff neck may even feign subarachnoid hemorrhage (SAH). In neuroimaging arachnoid cysts account for 1-2% of all intracranial pathologic masses. The most common location of arachnoid cysts is down the middle and rear of the skull in natural bodies of cerebrospinal fluid. Arachnoid cysts have a high rate of change. They can undergo spontaneous growth as well as the reduction or disappearance. Headaches, nausea or vomiting, worsening of mood, mental status changes, ataxia, seizures, hearing loss may be symptoms of serious intracranial pathology requiring diagnosis based on neuroimaging.
 ...
PMID:[Intracranial arachnoid cysts in the clinical and radiological aspect]. 2847 25

Arachnoid cysts(AC)are benign cystic lesions often diagnosed in childhood. Although usually asymptomatic, AC can become symptomatic when the lesion size increases or coexists with a subdural hygroma or hematoma. AC patients with signs of increasing intracranial pressure(IICP)or neurological deficits may need surgical intervention; this usually results in a good prognosis. However, whether asymptomatic AC patients should undergo surgical treatment is controversial. Although trivial head trauma, such as that from contact sports, can cause subdural hematoma in AC patients, there are currently no definite criteria regarding sports participation for children with AC. CASE: A 12-year-old boy who belonged to a soccer club visited an ophthalmologist with the chief complaint of having had diplopia for two weeks. He was identified as having bilateral papilledema. Since he had been diagnosed with a right middle cranial fossa AC five years earlier, he was referred to our outpatient clinic. Cranial CT scans showed right chronic subdural hematoma alongside the AC. The patient subsequently underwent burr hole surgery and was discharged after one week. In this case, the patient did not present with the typical signs of IICP, such as headache or vomiting. This experience indicates that care must be taken when encountering patients with atypical symptoms, particularly children. In addition, it is important to carefully consider sports participation for children with AC.
 ...
PMID:[Chronic Subdural Hematoma with Middle Cranial Fossa Arachnoid Cyst Concomitant with Bilateral Papilledema:A Case Report]. 3110 76

Arachnoid cysts are benign congenital malformations of the arachnoid which account for approximately 1.4% of the intracranial lesions. Although it is usually asymptomatic, it may be accompanied by headache, hydrocephalus and seizure. Psychiatric disorders associated with arachnoid cysts are rare. In this article, we present a giant arachnoid cyst with hypomania symptoms and marked cognitive impairment. A 44-year-old female patient was admitted to our outpatient clinic with a 4-year history of headache, nervousness and attention problems. Magnetic resonance imaging revealed a giant arachnoid cyst with a size of 5.5x10.5x12.5 cm was found in the left hemisphere of the patient. Considering the patient's irritability, increase in the amount of speech, flight of ideas, sleep disturbance and attention disorders, the diagnosis of hypomania was made. The neuropsychological tests showed that the speed of information processing, mental flexibility and attention functions decreased, and executive functions were impaired. The patient was consulted to the neurosurgery department. But no surgical treatment was offered. Drug therapy for hypomanic symptoms and cognitive impairment was planned, but could not be started since the patient did not attend to the follow-up exams. Albeit the lack of followup constitutes a limitation for our report, we believe that the size of the cyst, significant impairment of cognitive functions and the presence of hypomania symptoms might contribute significantly to the literature. Other cases with arachnoid cyst displaying cognitive impairment were summarized in our article.
 ...
PMID:A Case of Arachnoid Cyst Presenting with Cognitive Impairment and Hypomania Symptoms. 3259 1

Arachnoid cysts are responsible for 1% of expansive lesions in the central nervous system. Usually, they do not cause neurologic symptoms unless they have expansion or hemorrhage. Intracystic bleeding is caused by trauma or may be spontaneous. There are few cases in the literature of spontaneous hemorrhage of arachnoid cysts. This 2-dimensional video (Video 1) demonstrates the case of a 6-year-old boy who presented with headache and diplopia. At the physical examination, he exhibited right sixth nerve palsy. The complementary examinations revealed a left middle fossa arachnoid cyst classified as Galassi 2. An urgent procedure was planned to fenestrate the cyst. Informed written consent was obtained from the patient's family. Due to the team experience, endoscope-controlled microsurgery was performed. The patient experienced remission of the headache and the diplopia. A CT scan was performed on the first postoperative day and revealed a lamina of acute blood at the subdural space. It was an asymptomatic thin lamina of blood; we opted to watch and follow. One month later, a control MRI revealed a left frontoparietal subdural hematoma. Despite being asymptomatic, the hematoma was determined to have significant mass effect; thus, it was evacuated by a parietal burr-hole. After 1 month, another MRI showed resolution of the frontoparietal hematoma and significant reduction in the arachnoid cyst. There are few cases described of spontaneous rupture of arachnoid cyst; beyond that, we would like to illustrate a step-by-step procedure that is not widely available as a video article.
 ...
PMID:Endoscope-Controlled Microsurgery of a Ruptured Middle Fossa Arachnoid Cyst. 3313 Jan 31

Arachnoid cysts are benign masses that represent a relatively small percentage of intracranial lesions. Spontaneous rupture of an arachnoid cyst resulting in a subdural hygroma is a very rare event. We report a case of a pediatric patient with a history of an arachnoid cyst and chronic headaches presenting with bilateral papilledema, worsening headaches, and no history of head trauma. Magnetic resonance imaging of the brain revealed an extra-axial cystic lesion in the right middle cranial fossa, similar to an arachnoid cyst seen on previous imaging. A new right subdural collection similar to the cerebral spinal fluid signal causing mass effect on brain parenchyma was determined to represent a subdural hygroma. Craniotomy was performed to evacuate the subdural hygroma as well as cyst fenestration. We report this case to emphasize the importance of considering spontaneous rupture of an arachnoid cyst as a differential diagnosis despite absence of head trauma.
 ...
PMID:Subdural hygroma after spontaneous rupture of an arachnoid cyst in a pediatric patient: A case report. 3330 41


<< Previous 1 2 3 4