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Query: UMLS:C0018681 (headache)
 56,091 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 37-year-old woman suffered from headaches, right facial pain, double vision and occasional tinnitus. On examination there was only a slightly dilated right pupil, weakened corneal reflex and capillary bleeding from telangiectasia of both hands. Similar bleedings occured in her mother (mouth and hands) and son (nose). The arteriography of the right carotid artery showed a cavernous sinus fistula with a small shunt. Steady compression of the carotid artery by hand caused a marked improvement in the subjective symptomatology.
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PMID:[Spontaneous carotid cavernous fistula in a case of hereditary hemorrhagic telangiectasia (Osler-Rendu) (author's transl)]. 5 Oct 64

Eight months after sustaining a reversible left motor hemisyndrome, predominantly of the arm, a 47-year-old man known to have hereditary haemorrhagic telangiectasia (Osler's disease) again developed neurological symptoms (headache, vertigo, unsteady gait) with fever (up to 38.5 degrees C). Clinical features and findings on computed tomography indicated a cerebellar abscess. This was resected because it continued to enlarge despite antibiotic treatment with daily 2 g ceftriaxone and twice daily 0.5 g ornidazole. As another manifestation of Osler's disease further tests revealed an arteriovenous malformation (2.5 x 2.0 cm) in the right upper lobe of the lung, presumably the cause of the cerebral abscess. After wedge resection of the anterior upper lobe segment the further course was without complications.
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PMID:[Brain abscess as a complication of Osler's disease with lung involvement]. 193 26

In a retrospective serie the results of 72 cerebral vascular malformations, operated on consecutively were reviewed: 57 AV-malformations (in 55 patients), 1 dura AV-malformation, 9 cavernomas, 1 telangiectasia, 2 venous angiomas and 2 mixed malformations. The most frequent initial symptoms were headache, epileptic seizures and intracranial bleeding. In 5 cases the initial symptom was loss of consciousness with coma. A total resection could be proved angiographically in all cases. Mortality was 0%, neurological morbidity, i.e., new deficits or increase of existing deficits, was 8.6%. There were no recurrences of bleeding in the postoperative period. Quality of life, as assessed by the Karnofsky Index 6 months postoperatively, was satisfactory, approximately 80% of all patients being back at work. In this group of selectively operated patients it could be shown that localization of the malformation in or close to an eloquent brain area (n = 32) is rarely associated with significant persisting new deficits. Taking into consideration the natural history of AV malformations, with an 8% morbidity and 2% mortality each year, as compared to the surgical results, it is concluded that surgery may be more often indicated for AV malformations than was previously thought, even when they are near eloquent brain areas and relatively large in diameter.
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PMID:[Neurologic findings before and after removal of cerebrovascular abnormalities]. 203 13

A case of acoustic neurinoma with multiple intratumoral hemorrhages is reported. A 56-year-old male noted sudden hearing reduction in his left ear in October of 1985. The diagnosis of a local physician was sudden deafness. About 10 months later, he had two episodes of severe headache without nausea or vomiting. The patient was hospitalized in October of 1986. Neurological examination cerebellar ataxia. cerebellar ataxia. Plain and enhanced computed tomography revealed only an unremarkable low-density area at the left cerebellopontine angle. In contrast, magnetic resonance imaging (MRI) clearly demonstrated a large (3 x 4 x 5 cm), multicystic tumor in the site. On exposure of the tumor at surgery, most of the cysts were found to be filled with a dark red or xanthochromic fluid. The tumor was completely removed following numerous cyst punctures to decrease its volume. There was no evidence of subarachnoid hemorrhage. Histological examination showed a typical acoustic neurinoma. The cyst wall contained numerous telangiectasia-like lesions. The initial symptom of this patient was sudden hearing loss, which is an atypical manifestation of acoustic neurinoma. The massive intratumoral hemorrhage was thought to be caused by telangiectatic lesions in the cyst wall. MRI clearly demonstrated the hemorrhagic cysts within the tumor, especially in the posterior fossa.
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PMID:[Acoustic neurinoma presenting with repeated intratumoral hemorrhage. Case report]. 247 16

We reported a 41-year-old male with paramedian thalamic and midbrain infarcts due to cerebral embolism from bilateral pulmonary arterio-venous fistula and primary medullary hemorrhage. The patient had an episode of sudden onset consciousness disturbance with left Weber's syndrome (right hemiplegia and left oculomotor palsy) and vertical gaze palsy at age of 23. He noticed numbness in the left hand and the left half body under clavicular when he had got up in a morning at age 41. He had headache and left tinnitus on second and third days, and on the 3rd and 4th days, he experienced nausea. He had severe hiccup persisting from the 6th to the 13th days. The 23rd days he was admitted to our hospital. He showed dysesthesia and paresthesia in left half body under clavicular, dysesthesia in left hand and vertical gaze palsy and convergence disturbance. MRI performed on the 18th and 24th days, disclosed hyperdense mass in T1 and T2-weighted images in dorsal site of medulla, but the 70th days MRI showed no abnormal lesions. Therefore we diagnosed the high intensity mass as primary medullary hemorrhage. Cerebral angiography showed no abnormal vasculature. Many members of his family had history of sever nasal bleeding. He had skin hemangioma and mucosal hemangioma in esophagus, stomach, colon and rectum, and bilateral pulmonary arterio-venous fistula which had been operated at age 39. His mother also had skin hemangioma and pulmonary arterio-venous fistula. Therefore this family was diagnosed Rendu-Osler-Weber syndrome (hereditary hemorrhagic telangiectasia). MRI also disclosed multiple cerebral infarctions in bilateral thalamus, left cerebral peduncle and left cerebellar hemisphere.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:[Rendu-Osler-Weber syndrome presented paramedian thalamic and midbrain infarcts and primary medullary hemorrhage: a case report]. 269 33

A case of acoustic neurinoma which developed intratumoral hemorrhage extending to the right cerebellar hemisphere, is reported. A 54-year-old man was diagnosed as cerebello-pontine angle tumor, possibly acoustic neurinoma, from typical clinical course, neurological signs and findings of skull X-P and CT scan at the first visit to our out-patient clinic on July 28, 1981. On August 6, 1981, he was transferred to our in-patient ward in emergency because of sudden onset of headache and impairment of consciousness. At emergency admission, he was found to be comatous and CT scan revealed round-shaped high density in the right cerebellar hemisphere, continuing from the right cerebello-pontine angle tumor with enlarged lateral ventricles, which indicated occurrence of intratumoral hemorrhage. At emergency operation, hematoma in the right cerebellar hemisphere was evacuated and the tumor in the right cerebello-pontine angle was partially resected. Microscopically, the tumor was composed of compact, finely fibrillated cells of Antoni A tissues, and loose patterns of Antoni B tissue, being diagnosed as schwannoma, and also abnormal vascular proliferations were identified just adjacent to foci of hemorrhage noted within tumor tissues. The pattern of abnormal vascular proliferations within this tumor were almost identical with telangiectasia. The authors concluded that intratumoral hemorrhage in this case occurred most likely due to disruption of histologically verified abnormal vascular proliferations.
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PMID:[Case of acoustic neurinoma with intratumoral hemorrhage extending to cerebellar hemisphere]. 633 44

The clinical courses of 31 episodes of brain abscess and one episode of meningitis occurring in patients with hereditary hemorrhagic telangiectasia are reviewed. Pulmonary arteriovenous malformations were demonstrable in all but two patients and presumably permitted septic microemboli to evade the normal pulmonary capillary filter and lodge in the brain. Obtundation, headache, visual disturbances, hemiplegia, and seizures were the most common presenting features. Cyanosis, clubbing, polycythemia, and hypoxemia were routinely encountered, but leukocytosis and fever were present in a minority of cases, and all blood cultures were sterile. Anaerobic and microaerophilic streptococci were the commonest pathogens found in the brain abscesses. Thirteen patients died, and patients without abscess drainage or with delayed diagnosis had a higher mortality rate. A brain abscess may develop in approximately 1 percent of patients with hereditary hemorrhagic telangiectasia, and awareness of this risk should lead to early investigation of any patient with hereditary hemorrhagic telangiectasia who has neurologic symptoms.
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PMID:Central nervous system infections associated with hereditary hemorrhagic telangiectasia. 637 93

The authors described a case of arteriovenous malformation (AVM) of the choroid plexus, and presented a review of literature. This 40-year-old male experienced a sudden onset of severe headache and vomiting on February 5th 1982. At the other hospital, CT scans revealed marked intraventricular hemorrhage, however his general condition was relatively good without a loss of consciousness, motor weakness and sensory disturbance. After about a month of conservative treatment, he was transferred to the Kochi Medical School Hospital. On admission, he had shown no neurological deficit except for slight occipital headache. Transfemoral cerebral angiography revealed an angioma of the choroid plexus, which was fed by the anterior and medial posterior choroidal arteries and drained into the internal cerebral vein. CT scans showed a small high density area due to the nidus of angioma at the interspace of bilateral frontal horns of the lateral ventricles. On March 25th 1982, using an anterior transcallosal approach, the angioma was totally removed. The histological diagnosis was AVM. The post-operative course was uneventful and the patient discharged without adding neurological deficit on April 12th 1982. Review of literature revealed 27 documented cases of angioma of the choroid plexus; 12 cases of AVM, 5 of cavernous angioma, 2 of telangiectasia, 1 of venous angioma and the other 7 of undefined description. Almost all cases were initiated with an episode of variable intracranial hemorrhage, particularly of intraventricular hemorrhage. Clinical course of them, however, were variable. On the contrast to male prevalence of AVM located in the other sites, the ratio of female to male was 2:1.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:[Arteriovenous malformations of the choroid plexus--a case report]. 663 12

A familial optic atrophy with X-recessive heredity, distinct from Leber's optic atrophy (LOA), is described. The symptoms are: slight to moderate pallor of the papillomacular bundle at the disc possibly preceded by some hyperaemia of the disc, telangiectasia on the disc with normal retinal vessels, occurrence in the second decade of life, slow progression with often subclinical visual loss, a small relative central scotoma with an intact peripheral visual field, slight acquired tritanopia and deuteranopia, and vasomotor headaches. The disease may exhibit severe exacerbations with loss of vision to 1/60, provoked by vasoconstrictors and reacting favourably to vasodilators. This acute loss of vision is associated with ischaemia of the disc, a deep central scotoma with marked disturbance of colour vision in the form of an acquired deuteranopia, and sensoparalytic pupils. This is followed by increasing pallor of the disc, slow resolution of the central scotoma with a permanent reduction in the central light sensitivity, markedly disturbed Visual Evoked Potentials (VEP), acquired deuteranopia and normal ERG and EOG. In contrast to all hereditary opticopathies so far described, fluorescein angiography showed a disturbance of perfusion in the peripapillary choroid and the prelaminar part of the optic nerve. A similar disturbance of perfusion is described in anterior ischaemic optic neuropathy (AION) and low-tension glaucoma. To these acquired, non-hereditary recessive vascular opticopathies, which usually occur late in life, will have to be added the X-recessive vascular optic atrophy which we describe here, for which we propose the name: X-recessive angiopathic opticopathy. The differential diagnosis from some other hereditary, especially X-recessive, optic atrophies is discussed.
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PMID:X-recessive angiopathic opticopathy. 706 94

Multiple cerebral arteriovenous malformations occurred in a 48-year-old male complaining of headache, after orthopedic treatment for a leg fracture. He was free from neurological deficits and signs of hereditary hemorrhagic telangiectasia. Postcontrast computed tomography showed two abnormally enhanced lesions in the right occipital and left parietal regions. Magnetic resonance imaging showed these lesions as tiny vascular flow void signs, with neither new nor old hemorrhages. Angiography showed these lesions to be arteriovenous malformations. He declined treatment, and was followed as an outpatient.
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PMID:Multiple cerebral arteriovenous malformations--case report. 768 Jul 79


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