Gene/Protein
Disease
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Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
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Drug
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Target Concepts:
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Enzyme
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Query: UMLS:C0018681 (
headache
)
56,091
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Vernet syndrome is a unilateral palsy of glossopharyngeal, vagus, and accessory nerves. Varicella zoster virus (VZV) infection has rarely been described as a possible cause. A 76-year-old man presented with 1-week-long symptoms of dysphonia, dysphagia, and weakness of the right shoulder elevation, accompanied by a mild right temporal parietal
headache
with radiation to the ipsilateral ear. Physical examination showed signs compatible with a right XI, X, and XI cranial nerves involvement and also several vesicular lesions in the right ear's concha. He had a personal history of
poliomyelitis
and chickenpox. Laringoscopy demonstrated right vocal cord palsy. Brain MRI showed thickening and enhancement of right lower cranial nerves and an enhancing nodular lesion in the ipsilateral jugular foramen, in T1 weighted images with gadolinium. Cerebrospinal fluid (CSF) analysis disclosed a mild lymphocytic pleocytosis and absence of VZV-DNA by PCR analysis. Serum VZV IgM and IgG antibodies were positive. The patient had a noticeable clinical improvement after initiation of acyclovir and prednisolone therapy. The presentation of a VZV infection with isolated IX, X, and XI cranial nerves palsy is extremely rare. In our case, the diagnosis of Vernet syndrome as a result of VZV infection was made essentially from clinical findings and supported by analytical and imaging data.
...
PMID:Vernet syndrome resulting from varicella zoster virus infection-a very rare clinical presentation of a common viral infection. 2953 42
Context:
In West Nile virus (WNV) encephalitis,
polio
-like illness has been reported but there is no report on acute transverse myelopathy.
Design, Setting and Participants:
We report a patient with WNV myelopathy admitted in a tertiary care teaching hospital, India along with review of the literature.
Findings:
A 34 year-old lady presented with fever,
headache
, diarrhea, seizure, bulbar weakness and quadriplegia for 20 days. Her encephalopathy, bulbar and upper limb weakness improved within few days but flaccid areflexic paraplegia persisted till 6 months with a horizontal sensory level at D3. Electromyography was suggestive of anterior horn cell involvement and somatosensory evoked potential was unrecordable. MRI revealed middle cerebellar peduncle, pons and whole of spinal cord involvement. We could get 11 articles with spinal cord involvement in WNV infection in the medical literature through PubMed search. Their clinical, MRI and electro-diagnostic findings and outcome have been discussed.
Conclusion/Clinical Relevance:
Acute transverse myelitis may occur in WNV encephalitis and EMG may be helpful in confirming anterior horn cell involvement and predicting outcome.
...
PMID:Myelopathy in West Nile virus encephalitis: Report of a case and review of literature. 3012 85
Poliomyelitis
, also known as
polio
, is a highly infectious viral disease, predominantly affecting children under five years old. The virus is transmitted from person-to-person and mainly spreads through the fecal-oral route. The virus multiplies in the intestine, from where it can invade the nervous system via the bloodstream, potentially causing paralysis.
Polio
symptoms include fever, fatigue,
headache
, vomiting, neck stiffness and pain in the limbs. The disease causes permanent paralysis in one out of 200 infections. Currently, there is no cure for
polio
; it can only be prevented by immunisation.1.
...
PMID:Wild Poliovirus Type 1 in Oman: A re-emerging threat that requires urgent, targeted and strategic preparedness. 3219 Mar 63
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