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Query: UMLS:C0018681 (headache)
 56,091 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Forty-eight cases of the Vogt-Koyanagi-Harada (VKH) syndrome occurring in patients residing in southern California were reviewed. Thirty-six patients were Hispanic and 12 of other racial groups. Symptoms of meningismus, predominantly headache, were present in 32 (67%) cases, but the other characteristic neurologic symptoms, i.e., tinnitus and dysacusis, were present in only eight (17%) and six (13%) cases, respectively. Dermatologic changes were rare; vitiligo occurred in five (10%) patients, alopecia in six (13%), and poliosis in three (6%). In this patient population, extraocular signs and symptoms of the VKH syndrome, other than headache, were unusual. The ocular manifestations of the VKH syndrome are more constant and include iridocyclitis, vitritis, diffuse swelling of the choroid, serous retinal detachment, and optic disc hyperemia. Procedures that may aid in the diagnosis include lumbar puncture, fluorescein angiography, and standardized echography. The ophthalmologist must be prepared to make this diagnosis and initiate treatment with high-dose systemic steroids based on the typical ocular findings even in the absence of other (extraocular) manifestations of this disease.
Retina 1991
PMID:Variations in clinical features of the Vogt-Koyanagi-Harada syndrome. 196 85

Two patients with acquired immune deficiency syndrome presented with headaches and fevers. A diagnosis of cryptococcal meningitis was made by lumbar puncture and elevated cryptococcal antigens. Complaints of decreased vision in both patients led to the diagnosis of optic disc edema and cryptococcal choroiditis with yellow-white choroidal infiltrates noted in both eyes of the two patients. Systemic treatment with amphotericin B and 5' flucytosine led to resolution of the choroidal infiltrates. Late visual acuity loss was believed to be secondary to optic atrophy.
Retina 1990
PMID:Cryptococcal choroiditis. 234 88

The most common indications for treatment of patients with pseudotumor cerebri are the presence of severe intractable headaches and evidence of optic neuropathy. The role of the ophthalmologist in following patients with pseudotumor cerebri has been to document optic nerve dysfunction in terms of visual field abnormalities or loss of visual acuity. Macular changes have been described in association with papilledema. A case of pseudotumor cerebri and associated macular disease is reviewed to call attention to the need for the ophthalmologist to differentiate between visual loss secondary to optic neuropathy from that of macular disease. The case illustrates how quickly macular disease can develop. The management of patients with pseudotumor cerebri is discussed.
Retina 1989
PMID:Pseudotumor cerebri and macular disease. 247 98

A relationship between acute posterior multifocal placoid pigment epitheliopathy (APMPPE) and systemic infections has been suggested. This report presents a case of APMPPE in connection with acute nephritis in a previously healthy man. The disease started with arthralgia, headache, fever, malaise, and lymphadenopathy. During the following 2 weeks, signs of mild nephritis developed. At the same time the patient noticed acute decrease in vision; the visual acuity being 0.08 (20/250) in both eyes. Mild anterior uveitis and areas of pigment epithelial swelling at the posterior pole corresponding to the picture of APMPPE were observed. Four weeks later, the fundus lesions had healed leaving some pigment epithelial atrophy and pigment dispersion in the macula, and the visual acuity was 0.8 (20/25) in the right and 1.0 (20/20) in the left eye. No systemic therapy was given. This case gives support to the theory of general vasculitis as a cause of APMPPE.
Retina 1988
PMID:Acute posterior multifocal placoid pigment epitheliopathy in connection with acute nephritis. 342 Mar 12

The Heidelberg Retina Tomograph (HRT) II is a confocal scanning laser device used to acquire images of the optic nerve head. In this paper the authors report a novel use of this device in the assessment of papilledema in a patient with pilocytic astrocytoma of the pineal region. They also present a new technique to objectively produce 3D data of the optic nerve head. An 11-year-old girl presented with headache and bilateral papilledema; magnetic resonance imaging revealed a lesion in the pineal region. A suboccipital craniectomy was performed, and HRT images were obtained both before (baseline) and after (follow-up) the operation. The authors analyzed the height variation of the retinal surface along the vertical and horizontal cross-lines passing the center of the optic nerve head. The postoperative images, studied on the 2nd day after operation, demonstrated visible reduction of the papilledema. The height variation of the retinal surface along the contour line created by the software demonstrated that elevation of the optic nerve head became depressed due to resolved swelling. The height variation of the retinal surface along vertical and horizontal cross-lines demonstrated significant differences between the elevated preoperative curve and the postoperative curve (p < 0.001), consistent with improvement of her symptoms. Initial data suggest that changes in the optic nerve head topography after surgical decompression can be quantitatively documented by 3D data from the HRT II.
 ...
PMID:Monitoring papilledema in a patient with pineal pilocytic astrocytoma by using Heidelberg Retina Tomograph II. Case report. 1845 91

A 23-year-old woman with history of headaches and auditory changes presented with acute-onset visual field loss in the right eye. The combination of multiple retinal branch artery occlusions of the right eye on funduscopic examination, characteristic white matter lesions in the corpus callosum on magnetic resonance imaging, and hearing loss on audiometric testing led to a diagnosis of Susac's syndrome. Ultra-widefield fluorescein angiography revealed involvement of the retinal veins, which has not been previously reported with this condition. Additionally, ultra-widefield indocyanine green angiography demonstrated changes in the choroidal circulation, which are controversial in this syndrome.
Ophthalmic Surg Lasers Imaging Retina
PMID:Ultra-widefield fluorescein angiography reveals retinal phlebitis in Susac's syndrome. 2497 81

Central serous chorioretinopathy (CSCR) is an idiopathic disease associated with states of hypercortisolism that causes fluid to collect under the retina resulting in visual impairment. The authors describe an otherwise healthy female patient who presented with headaches and blurry vision after a 2-month history of excessive daily consumption of diindolylmethane (DIM), an over-the-counter estrogen modulator medication used to treat facial acne. Imaging demonstrated asymmetric, bilateral CSCR with active leakage in the left eye. She was instructed to discontinue DIM and reported that visual improvement began 2 weeks after, with resolution to baseline after 8 weeks.
Ophthalmic Surg Lasers Imaging Retina
PMID:Bilateral central serous chorioretinopathy associated with estrogen modulator diindolylmethane. 2542 41

A 60-year-old woman with a history of recurrent headaches and blurred vision presented with bilateral optic disc edema. Optic neuritis was suspected, and intravenous methylprednisonlone was administered. Her vision declined to hand motions in both eyes, and subsequent evaluation revealed bilateral acute retinal necrosis with bilateral central retinal artery occlusions (CRAO). Aqueous humor polymerase chain reaction analysis was positive for herpes simplex virus (HSV), establishing a diagnosis of HSV-associated bilateral acute retinal necrosis (ARN) and meningitis. CRAO has rarely been reported in association with ARN, and a fulminant course with bilateral CRAO in association with ARN has not been previously reported. This case emphasizes the importance of careful peripheral examination in patients with presumptive optic neuritis, judicious use of systemic corticosteroid in this context, and the retinal vaso-obliterative findings that may be observed in the pathogenesis of ARN.
Ophthalmic Surg Lasers Imaging Retina 2015 Feb
PMID:Bilateral central retinal artery occlusion associated with herpes simplex virus-associated acute retinal necrosis and meningitis: case report and literature review. 2570 59

An 82-year-old man presented with acute, painless vision loss in the left eye associated with headaches, jaw claudication, and scalp tenderness. Clinical examination and fluorescein angiography confirmed the diagnosis of a central retinal artery occlusion of the left eye. Spectral-domain optical coherence tomography (OCT) of the left eye showed paracentral acute middle maculopathy (PAMM), and OCT angiography showed severe attenuation of the deep capillary plexus. This is the first case report of OCT angiography of PAMM associated with central retinal artery occlusion confirming the presence of ischemia of the deep retinal capillary plexus.
Ophthalmic Surg Lasers Imaging Retina 2015 May
PMID:OCT Angiography of Paracentral Acute Middle Maculopathy Associated With Central Retinal Artery Occlusion and Deep Capillary Ischemia. 2605 63

The aim of this study is to report the coexistence of retinal arterial macroaneurysms (RAMs) and cerebral aneurysms (CAs) in a 58-year-old woman with hypertension. She was noted as having a 1-week history of vision loss in her left eye, along with a 2-month history of a nonspecific headache. Visual acuity was 20/32 in her left eye and 20/20 in her right eye. A fundus examination revealed multiple areas of retinal hemorrhages that were surrounded by circinate exudation in her left eye, as well as the generalized attenuation of the retinal arteries in both of her eyes. Angiographically, hyperfluorescent round leakage points confirmed the presence of five saccular RAMs. Surprisingly, computed tomography angiography completed based on the recommendation of neurology department identified three saccular CAs. Aging, hypertension, and female preponderance are the common risk factors for both RAMs and CAs. Accordingly, RAMs and CAs may exist simultaneously in hypertensive patients. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:79-82.].
Ophthalmic Surg Lasers Imaging Retina 2017 01 01
PMID:Are Multiple Retinal Arterial Macroaneurysms Considered a Sign of Cerebral Aneurysms? 2806 Mar 99


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