Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0018681 (headache)
56,091 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 52-year-old female presented with an unusual large cystic cavernous angioma with dense calcification in the thalamus manifesting only as headache despite the large mass with surrounding brain edema. Both T1- and T2-weighted magnetic resonance images revealed a large cystic mass with an intramural nodule appearing a reticulated, irregular mixed intensity core. The lesion was totally removed through a transcortical-transventricular approach. The postoperative course was uneventful with no signs of neurological deficit or residual mass 5 years later.
...
PMID:Large calcified cystic cavernous angioma in the thalamus--case report. 775 7

Cavernous angiomas of the dura mater are clinically and radiographically distinct from parenchymal cavernous angiomas. In this report, we present two cases of dural cavernous angiomas located outside the middle cranial fossa. The first patient is a 36-year-old woman with two dural cavernous angiomas, including one that enlarged during a 2-year period of observation. The second patient is a 33-year-old man with medically intractable seizures from a dural cavernous angioma of the convexity, which was discovered at autopsy. From our experience and a review of the literature, we have identified two groups of dural cavernous angiomas that differ in incidence, natural history, and surgical management. Most dural cavernous angiomas arise from the middle fossa; in contrast, only 15 cases of dural cavernous angiomas outside the middle fossa have been reported. Those in the middle fossa are more clinically aggressive and more difficult to resect surgically, because they grow toward the cavernous sinus and the parasellar region. Most patients with dural cavernous angiomas outside the middle fossa present with headaches, whereas those patients with dural cavernous angiomas in the middle fossa present with ocular signs, visual field defects, endocrinopathy, and trigeminal symptoms. Radiographically, both of the angiomas resemble meningiomas. Because of their intimate association with the cavernous sinus, surgical resection of middle fossa cavernous angiomas often is incomplete and may require postoperative radiosurgery to control growth. In contrast, angiomas in other locations are easily and successfully resected with little blood loss. The location of dural cavernous angiomas is an important factor in making the surgical decision and in predicting the outcome.
...
PMID:Dural cavernous angiomas outside the middle cranial fossa: a report of two cases. 780 Jan 41

We reported a rare case of multiple cavernous angioma accompanied with a convexity meningioma. A 41-year-old female developed generalized convulsion on October 8, 1985. Plain computed tomography (CT) scan revealed a round heterogeneous density mass in the right parietotemporal region, which was homogeneously enhanced. Angiography demonstrated a tumor stain fed by the right angular artery and the posterior branch of the right middle meningeal artery. Total removal of the tumor was performed. Since histological examination disclosed meningothelial cells, whorl formation, polymorphism and necrotic tissue, she received radiation therapy (total 50Gy) under the diagnosis of anaplastic meningioma. On November 10, 1988, she suddenly developed headache, nausea, motor weakness and homonymous hemianopia on the left side. CT scan revealed intracerebral hemorrhage (ICH) near the region where the meningioma used to be. Magnetic resonance image (MRI) demonstrated a high intensity mass at T1-weighted image and mixed intensity mass at T2-weighted image. Furthermore, there were multiple low intensity spotty lesions at the cerebral and cerebellar hemisphere in T1 and T2-weighted image. A few parts of these lesions showed central high intensity cores and perifocal low intensity areas, which were called ring formations or reticulated cores with black rims. The multiple lesions could not be detected by CT scan. ICH was evacuated. Histological examination revealed no specific pathology except necrotic tissue around the hematoma wall. Diagnosis of radiation necrosis was made. On October 25, 1992 she suddenly complained of left hemihypesthesia. CT scan demonstrated two high density spotty areas at the left caudate head and right thalamus. MRI showed these two lesions as reticulated cores with black rims.(ABSTRACT TRUNCATED AT 250 WORDS)
...
PMID:[Multiple cavernous angiomas accompanied with a convexity meningioma: a case report]. 781 76

The authors report 3 cases in which, in addition to venous angioma, other types of vascular malformations coexisted. They discussed the pathological significance of this coexistence, and the treatment to be given in these conditions. Case 1: A 38-year-old man was admitted to the hospital because of progressive headaches of 3 days' duration. X-ray CT revealed a large hematoma in the left cerebellar hemisphere. Vertebral angiogram showed a caput medusae in the venous phase, which is a typical picture of venous angioma. The hematoma was surgically removed and careful inspection of the cavity wall was made. A thick vein and many thin walled dilated venules draining to the vein were observed in the cavity wall. These abnormal vessels were completely removed. Because of reaccumulation of the hematoma and massive edema of the hemisphere, reoperation was performed. On removing a part of the cerebellar hemisphere, a small mass of vascular network was found and removed together with the hematoma. Histologically, the first specimen was a typical venous angioma, and the second one was a arteriovenous malformation. Case 2: A girl 9 years of age was admitted because of headache and left sided ataxia. CT and MRI revealed a multi staged hematoma in the left cerebellar hemisphere. Vertebral angiography, however, failed to demonstrate any kind of vascular malformations. The hematoma was removed with its wall. The histological appearance was compatible with venous angioma. 4 years later she bled again, and reoperation was performed. Histological examination this time revealed a cavernous angioma.(ABSTRACT TRUNCATED AT 250 WORDS)
...
PMID:[Venous angioma coexisting with other types of cerebrovascular malformations]. 807

Twenty cavernous angiomas were surgically removed after being localised by intra-operative echography. 10 patients were males and 10 females, with an average age of 34 years. Four patients had had intracerebral haemorrhage; all the remaining patients presented with headaches or seizures. The size of the lesion ranged from a minimum of 2.5 to a maximum of 4.0 cm. Its localisation was subcortical in 14 cases, paraventricular in 4 and in another 2 originated from the floor of the IV ventricle. Echography showed a blackberry-like cavernous angioma, hyperechogenous with respect to the surrounding parenchyma; the lesion was well-defined in all cases due to the absence of perilesional oedema with a clear demarcation from healthy tissue. After operation, pre-operative cranial nerve deficits (brought on by haemorrhage) only persisted in the two cases where the cavernoma involved the floor of the IV ventricle. In all cases post-operative radiological investigation recorded the complete removal of the cavernous angioma, the diagnosis of which was invariably confirmed by histological analysis. The authors draw the conclusion that intra-operative echography is capable of localising cavernous angiomas, providing the surgeon with real-time guidance during microsurgical removal. It is also useful for establishing as to whether complete removal has been accomplished.
...
PMID:The echo-guided removal of cerebral cavernous angiomas. 823 87

Cerebral venous angioma (CVA) is an embryonic venous malformation. Its incidence was thought to be radiologically rare previously but with greater clinical awareness, the routine use of contrast enhanced computerised tomography (CECT) and the increasing availability of magnetic resonance imaging (MRI), it is no longer perceived to be a rare lesion. In fact, it is the commonest intracranial vascular malformation seen at autopsy. We report our experience of 15 patients with cerebral venous angiomas, 14 of whom had their lesions confirmed by cerebral angiography. Presentation was variable and non-specific. The commonest presenting symptom was headache (n = 7). Other clinical presentations included epilepsy (n = 5), intracerebral bleed (n = 4, two were thought to be due to an associated cerebral cavernous angioma and one was due to a ruptured arteriovenous malformation) and non-specific giddiness (n = 3). Six were diagnosed incidentally. Based on the angiographic findings and the relatively benign clinical course in the majority of our patients, we believe that CVA is a developmental anomaly and should not be excised routinely.
...
PMID:Cerebral venous angioma--a misnomer? 826 55

We reported a case of chronic encapsulated intracerebral hematoma associated with cavernous angioma. A 71-year old female was admitted with a history of frontal headaches at intervals of about 3 months for the last one year. Plain CT scan showed a round mass of heterogeneous high density in the left medial frontal lobe. The outer surface of the mass was enhanced with contrast material. MRI demonstrated the mass as a high signal intensity on T1-weighted image and low intensity with laminated structure on T2-weighted image. MR angiogram depicted the mass as a mottled high signal intensity. The left internal carotid artery angiogram revealed no abnormal shadows and vessels. These findings suggested some form of a thrombus although its underlying pathogenesis was unclear. On January 20, 1992, a bifrontal craniotomy was performed. A whitish well-demarcated mass was seen in the left cingulate gyrus through a small corticotomy. We could not identify any branches feeding the mass. The cross-section of the mass disclosed a uniform thrombus encapsulated by a thick wall. Histological studies of the wall confirmed a cavernous angioma within the outer collagenous layers. Chronic encapsulated hematoma, which was first reported by Hirsh in 1981, has represented a separate entity and 25 such cases have been documented in the literature. These reports suggested that the compression and/or destruction of the surrounding tissue caused by the hemorrhage would mask the existence of the cavernous angioma or vascular malformation. If an encapsulated hematoma were encountered during an operation, surgeons should pay attention not to overlook the residual capsule encompassing the cavernous angioma or vascular malformation.
...
PMID:[Chronic encapsulated intracerebral hematoma associated with cavernous angioma: case report and review of the literature]. 832 61

A 38-year-old woman complained for about 5 years of attacks of headache elicited by coughing, sneezing, and laughing. These attacks became more frequent and more severe. Physical examination showed a short and broad neck. Neurological examination revealed no abnormality. Magnetic resonance imaging demonstrated the Chiari malformation (type I) and the cerebral venous angioma in left frontal white matter. A posterior decompression by suboccipital craniectomy with C1 laminectomy was performed. The headache completely disappeared. Before and after the operation, we measured the intracranial subdural pressure by a small pressure transducer. The raised cranial pressure by the Valsalva's maneuver prolonged for more than one minute. Postoperatively, the raised cranial pressure by the Valsalva's maneuver decreased rapidly. We consider that the cough headache of this patient was associated with a valve-like blockage by the Chiari malformation (type I) at the foramen magunum, resulting in cranio-spinal pressure dissociation by interference with downward pulsation. We believe that there was no correlation between the cough headache and the cerebral venous angioma.
...
PMID:[A case of cough headache with Chiari malformation (type I)]. 833 96

We reported a case of cavernous angioma in the middle cranial fossa, which was diagnosed with magnetic resonance imaging (MRI) and magnetic resonance angiography (MRA). The patient was a 56-year-old female, who presented with sudden onset right-sided headache with nausea. Her neurological findings were normal. On CT scan a high density area with a surrounding thin low density area was shown in the right posterior temporal region without contrast enhancement. Cerebral angiography of the left vertebral artery revealed only a small stain at the end of the right posterior temporal artery. On T2-weighted MRI after one month, the same region exhibited a central area of mixed signal intensities surrounded by a rim of decreased signal. MRA showed an area with remarkable 10mm mass with some contiguous vessels in the right posterior temporal region. That mass was resected operatively. It's pathological diagnosis was cavernous angioma. For diagnose of cavernous angioma, MRI and MRA were very useful. The specificity of these methods are superior to better than CT or angiography.
...
PMID:[A case of cavernous angioma--usefulness of magnetic resonance imaging and magnetic resonance angiography in diagnosis]. 839 89

A case of cavernous angioma of the pons which was surgically and successfully excised was reported. A 36 year-old man complained of progressive headache, double vision and tinnitus. Neurologic examination revealed left fifth, sixth and seventh cranial nerve palsies. He had left limb ataxia and right sided hemisensory deficit. A computed tomographic (CT) scan on admission disclosed a hematoma in the left lateral portion of the pons. Serial CT scans demonstrated progressive increase of hematoma. MRI scans revealed an area of mixed signal intensity in T1 weighted images. These findings were thought to be consistent with a cavernous angioma. Three months after the onset, surgery was performed using a lateral suboccipital approach. Histological examination disclosed cavernous angioma. After surgery, the patient's neurological deficits improved, and after 3 months, all symptoms except the mild limb ataxia had disappeared.
...
PMID:[Surgical removal of lateral pontine cavernous angioma: review of the surgically treated cases in the literature]. 842 94


<< Previous 1 2 3 4 5 6 7 8 9 10 Next >>