Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0018681 (headache)
 56,091 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Illusory splitting was illustrated as a visual migraine aura symptom in six of 562 Migraine Art pictures. In this type of illusion, objects or persons appear to be split, along fracture lines of varying form and orientation, into two or more parts that may be displaced and separated from each other. The illusion is strongly associated with the presence of elementary geometric hallucinations. Phenomenological similarities and differences of illusory splitting to the visual perceptual disturbances of fragmentation and mosaic illusion are discussed.
Cephalalgia 2000 May
PMID:Illusory splitting as visual aura symptom in migraine. 1099 72

Electromyographic (EMG) voltage that rises continuously during motor performance or mental activity and falls precipitately at the end is known as an EMG gradient. Our review is based on 55 studies of EMG gradients, which were published during the period 1937-1994. The extremely wide diversity of situations yielding EMG gradients suggests the possibility that these gradients may be universal accompaniments of organized goal-directed behavioral sequences, overt and covert. Motor tasks and cognitive tasks (without any requirements for motor output) were found to have this in common: they both produced EMG gradients. EMG gradients were not observed during simple, repetitive exercises. On the efferent side, we propose a dual model for the production of EMG gradients, which is based on empirical findings. This model is discussed in relation to current views on central and peripheral neural control of muscle contractions, and on the electrical properties of extrafusal and intrafusal muscle fibers, with particular reference to surface electromyography. The complex relations between EMG gradient steepness and mental effort seemed well represented by the dual model, which was also useful in the interpretation of certain EMG gradients that were found in patients with anxiety disorders, tension-type headaches, and auditory hallucinations, respectively. On the afferent side, drawing on data from human and animal studies, we consider the evidence for movement-related brain activity generated by proprioceptive input, in relation to different types of feedback to the central nervous system during tasks that produce EMG gradients. On electromyographic (EMG) gradients and movement-related brain activity: significance for motor control, cognitive functions, and certain psychopathologies.
 ...
PMID:On electromyographic (EMG) gradients and movement-related brain activity: significance for motor control, cognitive functions, and certain psychopathologies. 1102 75

The rare forms of migraine should be studied so that they can be recognized, thereby avoiding diagnostic errors and unnecessary complementary investigations. These rare forms can be divided into three categories: 1) atypical auras, characterized by the following: their semiology (visual or sensory illusions or hallucinations); their manner of onset (sudden onset of aura, with development of migraine in under four minutes); their duration (aura prolonged for between 60 minutes and seven days); aura with absence of accompanying cephalgia. This form of migraine could be confused with a case of partial epilepsy or AIT and raises a problem of differential diagnosis requiring an etiological investigation to ensure correct diagnosis; 2) clinical forms which are for the most part recognized by the International Headache Society's (IHS) classification, i.e., basilar artery migraine, familial hemiplegic migraine, ophthalmoplegic migraine and the rare occurrence of retinal migraine. Confusional migraine, a disorder which is mainly encountered in childhood, has not been categorized by the IHS but may be part of the symptomatology of the above-described forms; and 3) secondary migraines, in which a triggering mechanism causes migraine attacks to appear in a subject who was not previously affected by this disorder. This category covers post-traumatic migraine, migraine of cervical origin, the co-morbidity of migraine and epileptic seizures, and rare cases of symptomatic migraine which are indicative of underlying general disease or an intracranial lesion, i.e., a tumor or arteriovenous malformation.
 ...
PMID:[Rare and atypical forms of migraine]. 1107 45

There are three categories of rare forms of migraine headache. Atypical aura can raise difficult diagnostic questions due to their clinical expression (visual or sensorial illusions and hallucinations), their mode of onset (sudden aura, developing in less than 4 minute), their duration (prolonged aura lasting more than 60 minutes), and the lack of an accompanying headache. Differential diagnostics include partial epilepsy or AIT, requiring careful search for the underlying cause. Rare migraine syndromes are separate clinical entities, most of which are recognized by the International Headache Society (IHS). These syndromes include basilar migraine, familial hemiplegic migraine, ophthalmoplegic migraine and the exceptional retinal migraine. Confusional migraine, usually observed in children, is no individualized by the IHS but can be included here. For secondary migraines there is a triggering factor leading to migraine in patients with no history of migraine previously. These include post-traumatic migraine and cervical migraine as well as migraine occurring with epileptic seizures and rare symptomatic migraine headache disclosing a general disease or an intracranial neurological lesion.
 ...
PMID:[Rare and atypical forms of migraine]. 1113 47

Chronic hepatitis C virus (HCV) infection is quite prevalent in long-term hemodialysis (HD) patients. Patients who are candidates for renal transplantation might be treated, before grafting, with interferon-alpha (IFN-alpha). Among 39 HCV-positive long-term HD patients treated with IFN-alpha, we observed three cases of reversible posterior leukoencephalopathy syndrome (PLES). PLES included headaches in three patients, confusion in three patients, cortical blindness in two patients, visual hallucinations in one patient, seizures in three patients, and respiratory distress in one patient in a context of fluid overload and severe hypertension in all cases. The three patients were receiving IFN-alpha and recombinant erythropoietin therapies simultaneously for de novo anemia. Contrast-enhanced computed tomography scan or magnetic resonance imaging showed low-density areas in the occipital lobes (in three patients), frontal lobes (in one patient), and temporal lobes (in one patient). After withdrawal of IFN-alpha and recombinant erythropoietin therapies, hemodiafiltration, and symptomatic treatment of seizures and hypertension, PLES was reversible within 1 week in one patient, 10 days in one patient, and 2 months in the third patient. Our case reports show the occurrence of reversible PLES in HCV-positive long-term HD patients treated with IFN-alpha. Physicians caring for HCV-positive long-term HD patients treated with IFN-alpha need to be particularly cautious when these patients receive simultaneously recombinant erythropoietin and when IFN-alpha therapy induces a weight loss, which indicates a reduction in dry weight.
 ...
PMID:Reversible posterior leukoencephalopathy syndrome in hepatitis C virus-positive long-term hemodialysis patients. 1127 99

Twenty-six patients were studied who had the clinical and electroencephalographic features of benign childhood epilepsy with occipital paroxysms (BCEOP) as defined by the Commission of the International League Against Epilepsy (ILAE). Twelve patients were characterized as having early-onset benign childhood occipital seizures (EBOS) susceptible syndrome, as described by Panayiotopoulos, and 14 patients had late onset childhood idiopathic occipital seizures (LOS). Patients with symptomatic epilepsy and whose EEGs exhibited occipital spikes were excluded. The age of onset of the EBOS group ranged from 2.6 to 9.4 years (mean: 4.9+/-1.7 years), which was significantly younger than the LOS group (range: 4-12 years, mean:8.4+/-2.5 years). Both sexes were equally affected. The patients in the EBOS group had less frequent and longer seizures, ictal vomiting, more frequent deviation of the eyes, adversive seizures and more frequent nocturnal and secondary generalized seizures (P<0.05). By comparison, patients in the LOS group had a higher incidence of seizures, shorter duration of seizures and more frequent diurnal onset (P<0.01); also, although not statistically significant, the LOS group had more frequent visual hallucinations and headaches. The EEG topography in both groups showed at either side of occipital area typical paroxysms that were unilateral or bilaterally synchronous. Neither group had dipoles according to scalp voltage mapping. The clinical prognoses were favorable for both groups. To distinguish EBOS from LOS, detailed description of the age of onset, motor symptoms, visual symptoms, presence of eye deviation and diurnal or nocturnal occurrence are essential.
 ...
PMID:Clinical and electroencephalographic findings in early and late onset benign childhood epilepsy with occipital paroxysms. 1157 51

The visual illusion of a typical corona phenomenon was represented as a visual migraine aura symptom in six of 562 Migraine Art pictures, whereas another five pictures illustrated atypical variants of the said illusion. The extra edges of the corona phenomenon are commonly seen around the perceptual images of objects, but in atypical cases they can similarly surround illusory images and both elementary and complex hallucinatory images. The corona phenomenon is strongly associated with visual loss and the presence of elementary geometric hallucinations.
Cephalalgia 2001 Sep
PMID:Corona phenomenon as visual aura symptom in migraine. 1159 98

Reversible posterior leukoencephalopathy syndrome (PLS) is characterized by headache, altered mental function, visual disturbances and seizures. Neuroimaging studies suggest a white-matter oedema, predominantly in the posterior parietal-temporal-occipital regions of the brain. We present the case of a 30-year-old woman who had suffered her first attack of acute intermittent porphyria (AIP). Following 1 week of abdominal pain she developed several generalized seizures, and hallucinations, and exhibited a progressive deterioration of the consciousness. T2-weighted images, especially fluid-attenuated inversion recovery (FLAIR) sequences showed bilateral lesions in the posterior frontal, parietal and occipital cortex and subcortical white matter. Following treatment with haematin and a high carbohydrate diet the patient's condition improved. Follow-up magnetic resonance imaging (MRI) revealed complete resolution of the lesions. To our knowledge, this is the first report concerning a completely reversible PLS in AIP.
 ...
PMID:MR imaging of acute intermittent porphyria mimicking reversible posterior leukoencephalopathy syndrome. 1179 44

Since her early 30s a 72-year-old female migraine sufferer has experienced recurrent episodes of Lilliputian hallucinations occurring at the peak of her severe migraine attacks and lasting between 2 min and 5 min, suggesting that her miniature hallucinations represent a visual migraine aura symptom. The existence of Lilliputian hallucinations of a migrainous nature is confirmed by four similar case reports reviewed from the migraine literature. The occurrence of similar Lilliputian hallucinations in the syndrome of peduncular hallucinosis, due to mesencephalic and/or thalamic lesions, supports the notion that the patient's recurrent Lilliputian hallucinations might have been aura symptoms of basilar migraine.
Cephalalgia 2001 Dec
PMID:Recurrent Lilliputian hallucinations as visual aura symptom in migraine. 1184 72

We report a case of fatal intoxication with 2% viscous lidocaine. A 18 month old infant was admitted after malaise and cardiorespiratory arrest at home. He was resuscitated, then seizures appeared before arrival at the hospital. Treatment was symptomatic, including cardiorespiratory resuscitation and administration of anticonvulsants. Identification of lidocaine and its metabolite monoethylglycinexylidide (MEGX) MEGX was performed after organic extraction by High Performance Liquid Chromatography (HPLC) with Diode Array Detection (DAD); the serum concentrations, determined by Fluorescence Polarisation Immuno Assay (FPIA), were: 1.1 micrograms/ml for lidocaine and 0.94 microgram/ml for MEGX (H + 7) and 0.30 microgram/ml for the lidocaine (Day + 1). Neurotoxic manifestations appear at lower concentrations than cardiotoxic symptoms which are correlated with plasma levels of lidocaine. The toxic symptoms begin with headache, hallucinations, seizure, coma, respiratory arrest and circulatory collapse. The toxic symptoms can persist even after the decrease of lidocaine concentration under therapeutic levels. There is no antidote and acute lidocaine toxicity is managed with supportive therapy (diazepam for seizures, intubation, chronotropic agents). Considering the gravity of these poisonings which remain rare, the 2% viscous lidocaine prescription is forbidden for children under 6 years old.
 ...
PMID:[Fatal intoxication after accidental ingestion of viscous 2% lidocaine in a young child]. 1197 45


<< Previous 1 2 3 4 5 6 7 8 9 10 Next >>