Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0018681 (headache)
 56,091 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Case 1. A 38-year-old male was admitted with an 8-month history of progressive visual disturbance in his right eye. He had a past history of operations for paranasal sinusitis 24 years and 5 years prior to admission. Neurological examination revealed right anosmia, left hyposmia and vision in his right eye reducing to light perception. Case 2. A 61-year-old male was admitted with complaint of headache and a 2-month history of deteriorating vision in his right eye. On admission, vision in his right eye was found to be reduced to hand motions and associated with a concentric contraction of the visual field. Bilateral hyposmia and the right exophthalmos were also noticed. Plain x-ray films, tomography and especially CT scan were useful to demonstrate the definite inflammatory changes of the paranasal sinuses and the extension of the lesion beyond the confines of the sinuses. In both cases, external ethmoidectomy and sphenoidectomy with removal of the infected granulation tissue from the sinuses were performed, but neither mucocele nor pyocele was found. Vision improved postoperatively. Previous reports about ocular complications of infection in the paranasal sinuses without mucocele or pyocele are few. Early diagnosis of ocular complications of sinusitis is important. Once the diagnosis established, a timely surgical approach is essential to prevent visual loss.
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PMID:[Ocular complications in chronic pansinusitis--report of two cases]. 717 25

Bone infarction is a common occurrence in sickle cell disease. Described are three cases in which frontal headache, proptosis, and lid edema were seen with infarction of the orbital bone. Radionuclide scanning was useful in distinguished bone infarction from orbital infection in one case.
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PMID:Orbital infarction in sickle cell disease. 723 52

Symptoms and therapeutic results are reported in 21 cases of the sphenoidal ridge meningiomas. These meningiomas are usually not recognized in an early stage of typical of intracranial tumours. Headaches as an early symptoms were the complaint in only 10 cases. In the stage of clinical manifestations 9 patients had no visual disturbances, in 4 cases the eye fundus was not changed, in 13 there were no visual field defects. Unilateral exophthalmos was present in 5 cases, radiological changes in 13. The first five patients operated upon under local anaesthesia were lost, but out of the remaining 16 patients operated upon under general anaesthesia only 1 died of septicaemia three weeks after the operation. A considerable facilitation of the operation was the sitting position of the patients which make possible a good insight into the operation field (Fig. 1). At the time of collecting data about the fates of the patients 10 lived without help, six of them returned to their previous occupations, and 4 other ones were partly disabled because of poor visual acuity. Two patients required continuous care because of frequent epileptic seizures. One patient had recurrence after 3 years and was treated surgically again with success.
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PMID:[Immediate and remote results of surgical treatment of meningioma in the area of the small wing of the sphenoid bone]. 741 94

We treated a patient with a high flow traumatic carotid-cavernous fistula (CCF) by transarterial balloon occlusion. A 26-year-old male sustained an injury of the head. After 2 months he was admitted to our hospital due to exophthalmos, congestion of the palpebral conjunctiva. Right common carotid angiography showed a CCF with high flow shunt. He was treated by the endovascular balloon technique. Following the operation, abducens nerve palsy, headache, vomiting and convulsion developed and disappeared gradually within one week. Post operative 123I-IMP-SPECT revealed hyperperfusion of cerebral circulation compared to preoperative one. Post operative rt-carotid angiography showed pseudoaneurysm at cavernous portion of internal carotid artery. We discussed on abducent nerve palsy, pseudoaneurysm and hyperperfusion syndrome.
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PMID:[A case of atypical course after balloon occlusion for high flow traumatic carotid-cavernous fistula]. 766 18

A 62-year-old man presented with progressive diplopia, left ptosis, proptosis, complete ophthalmoplegia, facial numbness, and headache of 2 1/2 months' duration. The symptoms started 1 month after surgical resection of a squamous cell carcinoma in the left side of the forehead. Imaging studies helped localize the lesion, correlating with clinical features. The differential diagnosis is discussed. The final diagnosis was confirmed by autopsy.
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PMID:Ophthalmoplegia and facial numbness following treated squamous carcinoma of the forehead. 771 37

A 23-year-old soldier sustained a penetrating gunshot wound to the right frontoparietal region of the head in 1971 while serving in Vietnam. In 1984, he developed headaches and seizures, and a meningioma was found at the cranioplasty site. Recurrent meningiomas, requiring resection, developed at this site in 1988 and 1990. In 1994, he developed right proptosis. An extensive mass involving the right intraorbital region and the anterior and middle cranial fossa was found. Pathological examination of this tumor demonstrated malignant meningioma. Although antecedent head trauma has been implicated as a risk factor for meningioma, epidemiological studies of this association have yielded divergent conclusions. An explanation for this epidemiologic dichotomy is suggested.
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PMID:Posttraumatic meningioma: explanation of an epidemiologic dichotomy. 778 26

Mucormycosis, an uncommon opportunistic fungal infection, usually occurs in immunocompromised patients. It is rapidly progressive and almost always fatal. Patients with lymphoma are susceptible to pulmonary or disseminated mucormycosis, whereas rhinocerebral mucormycosis in such patients, as far as we know, is rarely reported. We present a patient with malignant lymphoma who exhibited such an acute rhinocerebral infection after chemotherapy which manifested initially as a stuffy nose and intractable headache. Then ptosis, proptosis, chemosis and multiple cranial nerve palsies appeared. Eschar was found in the nasal cavity. Direct KOH smear and tissue biopsy revealed mucormycotic infection. He survived because of early diagnosis and prompt treatment.
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PMID:[Rhinocerebral mucormycosis in a case of malignant lymphoma]. 785 31

The neurosurgical manifestations in three patients with sphenoid sinus mucoceles and two others with fronto-ethmoidal mucoceles are presented. In two patients, sphenoid sinus mucoceles produced visual loss while in the other severe headache was the only symptom. Both patients with fronto-ethmoidal mucoceles presented with proptosis. All patients had surgical treatment. While other symptoms were relieved following treatment, visual loss remained unchanged in both patients in whom it was present. We recommend a high level of suspicion for mucoceles as a cause of sudden or progressive visual loss. Prompt surgical therapy is needed to achieve good visual outcome.
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PMID:Mucoceles: a neurosurgical perspective. 801 Nov 95

Partial ophthalmoplegia due to third nerve palsy with an intact pupil is a frequent cause of diploplia observed in diabetic patients. Pupillary muscle involvement, such as anisocoria and loss of light reflex, is usually uncommon in this diabetic cranial mononeuropathy. A 65-year-old woman with non-insulin dependent diabetes mellitus (NIDDM) suddenly developed a severe headache and diplopla. Right oculomotor nerve palsy was observed in association with anisocoria, ptosis of the right lid, and a defective light reflex. No exophthalmos or vascular bruit was observed in the right orbital region. Computed tomography and magnetic resonance images of the head were negative. Cerebral angiography revealed a carotid cavernous sinus fistula (CCF). The patient was successfully treated with external carotid artery embolization combined with radiation. It is well known that pupil sparing in oculomotor nerve palsy predicts an extraaxial ischemic lesion, while pupil involvement predicts an extraaxial compression lesion. Therefore, pupillary involvement in oculomotor nerve palsy in diabetic patients necessitates cerebrovascular investigation to rule out ICPC aneurysm or tumor. In this circumstance, a variant type of CCF without characteristic ocular signs should be included in the differential diagnosis.
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PMID:[A case of NIDDM associated with oculomotor palsy due to atypical carotid cavernous sinus fistula]. 827 44

Sphenoid sinus mucoceles are rare lesions. Those with intracranial extension were thought to be extremely rare in Western literature. We encountered three such cases within 1 year. These cases were confirmed on pathological examination to be pyoceles of the sphenoid sinus, extending to the sella and suprasellar region. Bilateral exophthalmos, papilledema, and severe headache were among the most consistent findings encountered. It appears that these lesions might be more common in areas of poor socioeconomic status like Third World countries. This condition should be considered in the differential diagnosis of lesions of the sella extending to the suprasellar region.
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PMID:Sphenoid sinus mucopyocele with marked intracranial extension: a more common phenomenon in the Third World? 835 23


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