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Query: UMLS:C0018681 (headache)
 56,091 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Cerebral sparganosis is caused by the migrating larva of Spirometra mansonoides. Only seven cases have been reported worldwide. We here report the second known case in the United States. Including our case, ages ranged from 24 to 46 years. Men and women were equally affected. Headache, convulsions, focal neurologic signs, and peripheral eosinophilia were common. CT often revealed an enhancing mass. Surgical resection of the parasitic granuloma gave excellent results. often revealed an enhancing mass. Surgical resection of the parasitic granuloma gave excellent results.
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PMID:Cerebral sparganosis. 374 93

In 1963, acute trichinosis was recognized in four patients at the Ottawa Civic Hospital. One presented with cavernous sinus thrombosis and sixth nerve palsy. A second had a severe systemic infection with myocarditis; the signs of myocarditis appeared in the third week. Electrocardiographic abnormalities included T-wave flattening, prolongation of PR interval and QRS complex, and non-specific changes in 25%. Central nervous system involvement occurred in the second week with general symptoms (headache, delirium and psychotic behaviour), followed in the third week by focal signs (nerve palsy, convulsion, pareses and coma).The incidence of trichinosis in the U.S.A. fell from 15.9% before 1948 to 4.5% in the period 1948-1963. The Canadian incidence in the period from 1940 to 1943 was 5.6%. In a survey in Ottawa using the Baermann digestion and compression methods, four positive cases were found out of 500 diaphragms examined. These figures indicate the success of the public health regulations aimed at controlling trichinosis. A gastrocnemius muscle biopsy is still an invaluable diagnostic tool, especially in critically ill patients with negative skin tests and no eosinophilia.
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PMID:Human trichinosis: report of four cases, with emphasis on central nervous system involvement, and a survey of 500 consecutive autopsies at the Ottawa Civic Hospital. 428 27

In the past four months a new syndrome has caused more than 100 deaths in Spain. The most striking feature is a toxic-allergic pneumonopathy with respiratory distress and radiological evidence of interstitial (occasionally alveolar) exudation. Other features are fever, headache, nausea, muscular and abdominal pains, rash, hepatosplenomegaly, and eosinophilia; later, thrombotic phenomena and neurological disorders may appear. The epidemic has been traced to ingestion of rapeseed oil, denatured with aniline and containing acetanilide. The syndrome does not resemble intoxication with aniline or acetanilide, and is provisionally ascribed to "oleoanilide", a product formed by reaction of acetanilide with fatty acids.
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PMID:Toxic-allergic syndrome caused by ingestion of rapeseed oil denatured with aniline. 611 11

The initial symptoms of a new multisystem disease probably caused by ingestion of denatured rapeseed oil were acute pleuropneumopathy, fever, headache, exanthems, myalgia, and eosinophilia. Later features were severe myalgia and thromboembolic accidents. The present phase of the illness is typified by scleroderma-like involvement, pulmonary arterial hypertension, and a neuromuscular syndrome. Nearly all the patients with these late changes are women. The pathological lesion is a peculiar form of non-necrotising vasculitis which primarily affects the intima.
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PMID:Toxic epidemic syndrome, Spain, 1981. Toxic Epidemic Syndrome Study Group. 612 35

A case of cerebral schistosomiasis with a huge calcification and with a long clinical course was reported. A 39-year-old male developed ataxic gait gradually associated with headache and general fatigability. According to the past history, the patient had suffered from severe meningitis with disturbance of consciousness for 2 weeks when he was 10 years of age. Neurological examination revealed positive Romberg's sign and left homonymous hemianopsia. Plain craniogram showed a large calcification occupying the whole right occipital region. This calcification was lobulated in shape and was 11 X 9 X 9 cm in size. CT scan demonstrated calcification and remarkable hydrocephalus. This calcification had no mass effect. Left vertebral angiogram revealed the right parieto-occipital artery to be stretched and slightly displaced toward midline. Hematological analysis disclosed no abnormality except for eosinophilia (10%). Pre-operative diagnosis was an old calcified granuloma of unknown origin. For the purpose of biopsy, a right occipital craniotomy was performed. On reflecting the dura, fibrous adhesion and vascular network were seen between the inner table of the dura and the arachnoid. Subarachnoid space was enlarged and all cortical vessels were narrow in their diameters. By a corticotomy, a whitish-yellow calcified mass was seen in the depth of 2 mm. The yellowish gelatinous content poured out of the mass. A piece of calcification and a small amount of content were taken as specimen. Microscopic study of the calcified tissue showed many egg shells of schistosoma japonica, necrotic tissues and infiltration of small round cells.
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PMID:[Cerebral schistosomiasis with a huge calcification. A case report]. 646 58

The authors study the results of a treatment of 700 cases of bilharziasis seen in Paris and in two foci in Togo, by oxamniquine, oltipraz or praziquantel. The three drugs are well tolerated; only a few mild side-effects were reported such as discomfort, nausea, headaches (two cases of acrodynia with oltipraz ). The three drugs are very efficacious in the case of schistosomiasis mansoni (85,5% success rate with oxamniquine, 92,9% with praziquantel, from 76,5 to 92% with oltipraz depending on the different strains) at day 180. As far as schistosomiasis haematobium is concerned, oltipraz and praziquantel have a 87,5% success rate with oltipraz and 80% with praziquantel; however, in the case of oltipraz , it is necessary to increase the dose. The action of praziquantel seems to be slower on Schistosoma haematobium than on S. mansoni. By the study of the evolution of antibodies, the fast action of praziquantel was noticed, explaining the peak of serological titers and of eosinophilia as early as day 10 after treatment; in the case of oltipraz , the apparition of this peak is only recorded at the 30th day. The slower effect of oltipraz on worms implicates not to judge its efficacy by too early controls.
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PMID:[Treatment of 700 cases of bilharziasis with the new drugs oxamniquine, oltipraz, praziquantel]. 667 43

We gave intravenous amrinone to 40 patients in heart failure, and oral amrinone to 18 patients. Acute intravenous administration caused a significant reduction in mean blood pressure and this was severe enough to require correction by plasma infusion in five patients. Oral amrinone was accompanied by thrombocytopenia in 10 patients but no complications were associated with the low platelet count. Other potentially serious adverse effects were: abdominal pain (two patients), nausea and vomiting (three patients), jaundice (one patient), myositis (one patient), pulmonary infiltrates (two patients), and polyserositis (one patient). Less serious adverse effects observed were: splenomegaly, eosinophilia, fever, headache, reduced tear secretion, dry skin, and nail discoloration. The potentially severe adverse reactions with amrinone need to be weighed carefully against its benefits in the treatment of heart failure.
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PMID:Side effects of amrinone therapy. 683 32

Cysticercus racemosus in a tumour-like mass from the brain of a 30-year-old Canadian was identified by histological and specific immunofluorescent techniques. The patient possibly acquired the infection during her stay in India. She had a mild peripheral eosinophilia and complained of pounding headaches and convulsions. Examination of tissue sections revealed the larva enclosed in an eosinophilic phlegmon and the surrounding brain tissue infiltrated by histiocytes and eosinophils. Loss of microtriches and degenerative changes in the larva were apparent in areas with adherent eosinophils. With the appropriate reagents, both intracellular and interstitial specific immune complexes were detected in the biopsied tissue. The course of infection in the cystic and racemosus types of cysticercosis and the role of tissue eosinophilia in neurocysticercosis have been discussed.
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PMID:Cysticercus racemosus in an eosinophilic phlegmon in the brain. 703 36

The Toxic Syndrome (TS) caused by ingestion of adulterated rapeseed oil in Spain is a new disease of multisystemic character whose aetiology and pathogenesis remains unknown. The most prominent pathological feature is a peculiar non-necrotizing vasculitis, that affects mainly the intima and involves vessels of every type and size in practically every organ. The TS begins with an acute clinical picture with pleuropneumopathy, fever, headaches, exanthems and eosinophilia. In these early clinical phases the main pathological findings were observed in the lungs and consisted of intense pulmonary interstitial oedema with scanty inflammatory mononuclear infiltrates. Ultrastructural study revealed hydropic degeneration of pneumocytes types I and II with desquamation of type I. The patients in this phase died of respiratory failure, later deaths were due to thromboembolic complications. Later still the patients developed a neuromuscular syndrome, sclerodermiform skin lesions and severe weight loss and died predominantly of infectious complications and respiratory failure. The anatomopathological picture in the peripheral nerves was that of inflammatory neuropathy with a lymphocytic perineuritis that led to perineural fibrosis with secondary axonal degeneration. The muscle presented an interstitial inflammatory myopathy at first followed by a neurogenic muscular atrophy. The skin lesions in the late phases consisted in dermal or dermal and subdermal fibrosclerosis, with vasculitis of the small arteries in the lower dermis. The salivary glands and pancreas showed vasculitis and interstitial inflammation which progressed to interstitial fibrosis and parenchymal atrophy.
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PMID:Pathology of a new toxic syndrome caused by ingestion of adulterated oil in Spain. 715 66

The Katayama syndrome, the early stage of schistosomal disease, occurs 3 to 6 weeks after infection. The main symptoms are fever, urticaria, oedema and general malaise. Eosinophilia is a constant finding. The syndrome developed in a group of Dutch tourists after a visit in early November 1975 to the Omo National Park, southwest Ethiopia. Eight out of 10 infected persons became clinically ill. The incubation period varied from 4 to 41 days with a mean of 26 days. Pyrexia occurred in 6 patients, usually associated with headache and muscle pains; only to one patient the fever lasted for more than two weeks. Fever followed by oedema was present in one patient. Two patients were afebrile, one suffered from urticaria, the other from general malaise. Two visitors remained asymptomatic, but the results of serological tests showed that they were also infected. The liver function was disturbed in one patient during the febrile period and further deteriorated during treatment with niridazole. S. mansoni eggs were detected in small numbers in two patients, 6 months and 19 months after infection. Obviously the tourists harboured few adult worms. They probably had been infected by few cercariae; the possibility that they were infected by cercariae of a S. mansoni strain not well adapted to man was considered.
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PMID:The Katayama syndrome; an outbreak in Dutch tourists to the Omo National Park, Ethiopia. 724 38


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