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Query: UMLS:C0018681 (headache)
 56,091 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Seventeen male and 39 female Liberian patients, one third of them children, were diagnosed as having hyperreactive onchodermatitis (sowda). They presented with itching (98%), asymmetric (98%), chronic onchodermatitis (median 5 years), and swelling of femoral lymph nodes (89%). The geometric means of the microfilaria (mf) densities were 1.0 mf/mg in children and 0.7 mf/mg in adults. These patients not only suffered from their skin lesions, and severe itching resulting in disturbance of sleep but also from social stigmata. They urgently needed treatment. Ivermectin was administered as a single oral dose of 150 micrograms/kg body weight. The following adverse effects were observed in 30 patients within the first 72 hours after ivermectin treatment: increase of pruritus (93%), aggravation of dermatitis (73%), fever (25%), headache (20%), myalgia (20%), painful swelling of lymph nodes (13%) and severe swelling of arm or leg (10%). Symptomatic therapy was sufficient. No dangerous or life-threatening side effects were observed. At follow-up examinations 1-2 months after ivermectin treatment, the prevalence of mf carriers had decreased from 100% to 19%. Seventeen out of 18 patients felt their dermatitis had improved. Evaluation of the dermatitis by a physician using a score from 0 (no dermatitis) to 9 (severe dermatitis) revealed a reduction of the score from 4.3 before treatment to 0.7 (84%) after ivermectin. In contrary, at the follow-up examination of 16 patients 6-12 months after ivermectin some recrudescences were observed. In this group the prevalence of mf carriers was 47%, 13 out of the 16 patients felt their skin lesions had improved and the score had decreased from 2.2 to 0.5 (77%). Consequently, it is recommended to administer ivermectin to patients with hyperreactive onchodermatitis every 3-4 months.
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PMID:Ivermectin treatment of hyperreactive onchodermatitis (sowda) in Liberia. 882 99

Disinfectant surveys from responding members of the American Society of Postanesthesia Nurses were divided into two groups based on whether or not they considered themselves to be exposed to disinfectants in their work environment. Their survey responses were then compared with those obtained previously from members of the Society of Gastroenterology Nurses and Associates, Inc., who were regularly exposed to 2% alkaline glutaraldehyde in the work setting. There were significant differences among the groups in the percentage of respondents who reported having headaches, eye irritations, respiratory problems, shortness of breath, rashes, memory loss, mood swings, and fatigue. These findings support the association of these complaints with 2% alkaline glutaraldehyde exposure. In contrast, there were no significant differences among the groups in the percentage of respondents who reported having asthma, rhinitis, chest pain, nausea, diarrhea, muscle/joint pain, visual disturbances, or dermatitis.
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PMID:Society of Gastroenterology Nurses and Associates, Inc. (SGNA) Endoscopic Disinfectant Survey results compared with control group. 902 1

The frequency of symptoms and signs in 52 patients with chronic Lyme borreliosis was analyzed in the study. The significantly higher frequency of: headache, myalgias, cranial neuritis, chronic dermatitis, ataxia and arrhythmia (p < 0.05) was found in the group of untreated (n = 31) in the early phase compared to the frequency of the same symptoms in the group that was treated (n = 21). The neuropathy of sensitive type was more frequently noticed in that group (p < 0.01). The treatment of patients with Lyme borreliosis in the early stage should be started as soon as possible and should be performed until the probable elimination of significant decrease of causative agents number in the tissues.
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PMID:[Clinical characteristics and perplexities in the treatment of chronic Lyme borreliosis]. 926 75

The federal country of Carinthia is known for its lakes and ponds, which are extensively used for bathing. The water quality is monitored regularly in accordance to the EC-Directive 76/160/EC and especially to the more rigorous Austrian Standard M6230. Since redevelopment measures of the lakes have been nearly finished the water quality found has improved essentially. In spite of these monitored data no effective correlation to data from the concerning ambulant sector of medical care could be established. The Carinthian Sentinel Practice Network started in summer 1994 to retrieve informations about occurrence and frequency of bathing related illness of children up to 16 years old. The 26 participating primary health care and pediatric physicians, having their own independent practices spread all over the country, reported the specific doctor-patient-contracts to the coordinating base. Criteria for inclusion in the medical report were headache, sore throat, otalgia, stomach-ache, nausea, emesis, diarrhoea, fever, rhinitis, cough, cold, moreover conjunctivitis, skin rash and specific dermatitis. In addition physicians reported where, how long and how often the children had been bathing and how long they had been free of symptoms afterwards. Each case was reported to the coordinating base including a presumed diagnosis. Statistic evaluation showed that bathing related illness may be divided into three main groups according to symptom frequency. The frequency of otalgia (32.4%) was significantly higher than any other symptom asked for. Two groups of symptoms correlate with each other: on one hand rhinitis, conjunctivitis, cough and sore throat (36.5%) and on the other hand nausea, emesis, diarrhoea and fever (41.9%). These data underline conclusions drawn by other authors but are not representative enough to correlate to data from water monitoring. First results suggest that conclusions for public health authorities can be drawn from this additional information about the state of the lakes and ponds-providing a sufficient number of data is reported.
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PMID:[Bathing water related diseases: the Carinthian Sentinel Project as the source of epidemiological data]. 937 46

A case of sinusitis caused by the basidiomycete Schizophyllum commune is reported in a 36-year-old female with a history of allergic rhinitis and dermatitis. The patient presented with sudden nasal obstruction, purulent nasal discharge, headache and general discomfort. Computer tomography revealed extensive opacity of the left maxillary sinus as well as erosion of the nasal wall and maxillary bone. Mycological examinations of nasal discharges and material aspirated during anthrostomy showed hyaline, septate hyphae with rare spicules. Primary isolation yielded a white, woolly mould which demonstrated clamp connections and basidiocarp primordia but these characteristics were lost in subculture. Identification was confirmed by vegetative compatibility studies. The patient was treated with itraconazole to avoid possible postsurgical dissemination. Three months after cessation of therapy, no recurrence of infection had occurred.
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PMID:Maxillary sinusitis caused by Schizophyllum commune and experience with treatment. 940 31

An increasing number of persons say that they get cutaneous problems as well as symptoms from certain internal organs, such as the central nervous system (CNS) and the heart, when being close to electric equipment. A major group of these patients are the users of video display terminals (VDTs), who claim to have subjective and objective skin- and mucosa-related symptoms, such as pain, itch, heat sensation, erythema, papules, and pustules. The CNS symptoms are, e.g. dizziness, tiredness, and headache. Erythema, itch, heat sensation, edema and pain are also common symptoms of sunburn (UV dermatitis). Alterations have been observed in cell populations of the skin of patients suffering from so-called "screen dermatitis" similar to those observed in the skin damaged due to ultraviolet (UV) light or ionizing radiation. In "screen dermatitis" patients a much higher number of mast cells have been observed. It is known that UVB irradiation induces mast cell degranulation and release of TNF-alpha. The high number of mast cells present in the "screen dermatitis" patients and the possible release of specific substances, such as histamine, may explain their clinical symptoms of itch, pain, edema and erythema. The most remarkable change among cutaneous cells, after exposure with the above-mentioned irradiation sources, is the disappearance of the Langerhans' cells. This change has also been observed in "screen dermatitis" patients, again pointing to a common cellular and molecular basis. The results of this literature study demonstrate that highly similar changes exist in the skin of "screen dermatitis" patients, as regards the clinical manifestations as well as alterations in the cell populations, and in skin damaged by UV light or ionizing radiation.
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PMID:Skin changes in "screen dermatitis" versus classical UV- and ionizing irradiation-related damage--similarities and differences. 941 15

All-trans retinoic acid (ATRA) induces complete remission (CR) in most cases of acute promyelocytic leukemia (APL). Toxicity of ATRA has been shown to be mild and consist of headache, dry skin, dermatitis, gastrointestinal disorders, and hypertriglyceridemia. We report three patients with APL treated with ATRA in combination with chemotherapy, who developed scrotum exfoliative dermatitis with ulceration. Their age was 33 years (range, 25 to 37). All three cases developed scrotum erosions, and many small ulcers after 9 to 17 days of ATRA treatment. The scrotum exfoliative dermatitis with ulceration occurred repeatedly, but gradually resolved in about 8 weeks time. They developed no dryness of the lip or skin apart from the scrotum. All three cases continued to receive 45 mg/m2 of ATRA daily throughout induction therapy, and achieved CR. We suspected the scrotum exfoliative dermatitis with ulceration to be a side effect of ATRA. The scrotum lesions, which have been already reported may be common in patients receiving ATRA.
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PMID:[Scrotum exfoliative dermatitis with ulcers associated with treatment of acute promyelocytic leukemia with all-trans retinoic acid]. 949 53

Migrant farmworkers lead a hard life filled with strenuous work, stress, and anxiety about employment; live under substandard conditions; and rarely get the health care they require. Preventive care is a luxury they cannot afford. Year-round nutritious meals are rarely possible, due to long working hours, traveling, and living in housing without adequate cooking and refrigeration facilities. Children may attend up to six or more schools during the course of a school year. Crowded housing conditions support the invasion of parasites, infectious diseases, and viral infections. Dermatological conditions from working around a wide variety of plants, dirt, and in the sun are frequent. Exposure to pesticides, herbicides, and other chemical additives creates the likelihood of acute reactions, such as headaches and rashes, and also puts workers at risk of developing chronic diseases as the level of exposure rises because of accumulation and mix of various chemicals. Yet, we know little about the health status of this population. We are unable to estimate crude death rates, age-specific death rates, or prevalence rates of most common causes of death, such as heart disease,cancer and stroke. There is no information about occupational accident rates, infectious disease rates, or even postneonatal mortality. We do know that when migrants go to a clinic, they are often likely to have the chronic conditions of hypertension or diabetes. They present symptoms of acute conditions such as dental problems, dermatitis, otitis media among children, and acute upper respiratory infections. Women frequently need obstetrical care, reflected (ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:Health status and needs of migrant farm workers in the United States: a literature review. 1012 52

Various chemicals found in the environment have been suspected of initiating or contributing to conditions such as asthma, dermatitis, irritability, headaches, cardiac arrhythmias, thrombophlebitis, and vasculitis. The increasing number and variety of chemicals present in the environment has led to the hypothesis that there may also be a corresponding increase in the number of people who are sensitive to these chemicals. Sensitive individuals may be continually exposed to chemical insults in their normal environment and may be experiencing a chronic reaction; however, an exposure-response relationship is difficult to establish. An Environmental Care Unit (ECU) provides an atmosphere that minimizes exposures to potential insults so patients symptoms of reaction to chemical insult may be relieved before challenge testing. Air quality required within an ECU to achieve this symptom remission is not known; therefore, this study was designed to document and compare concentrations of six criteria pollutants (sulfur dioxide, carbon monoxide, nitrogen dioxide, hydrocarbons, total suspended particular, and ozone) and formaldehyde within the ECU, the hospital outside the ECU, and the ambient atmosphere of the neighborhood around the hospital. Air movement studies indicated that the ECU was under positive pressure with respect to the rest of the hospital and had an air supply to air exhaust ratio of approximately two. Overall, no significant differences were found for any sampled pollutant at sites within the ECU or between ECU sites and the hospital proper. With an exception of ozone, significant differences among contaminant concentrations were noted between the atmosphere of the surrounding neighborhood and the hospital proper.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:The determination of ambient air quality within an environmental care unit. 1028 81

Since 1972, companies have extracted almost two billion barrels of crude oil from the Ecuadorian Amazon (Oriente), and in the process have released billions of gallons of untreated toxic wastes and oil directly into the environment. Indigenous federations and environmental groups in Ecuador have organized in opposition to unregulated oil development, charging that contamination has caused widespread damage to both people and to the environment. Yet, faced with a weak economy and pressure from foreign creditors, the government is rapidly proceeding with plans to increase oil production. Little human rights advocacy or scientific research has been done on health effects of oil contamination in the Oriente. Exposure to crude oil and its constituents is harmful to human health, ranging from minor symptoms such as headache, nausea, and dermatitis to cancers and adverse effects on reproduction and immune response. This paper is one of the first attempts to apply the right to health and a healthy environment in assessing the human consequences of a country's development policies.
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PMID:Rights Violations in the Ecuadorian Amazon: The Human Consequences of Oil Development. 1039 12


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