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Query: UMLS:C0018681 (headache)
 56,091 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Serum testosterone level was determined by radioimmunoassay in 57 men, including 23 cases of Horton's neuralgia during the period of recurrent headaches but not during an attack of headache, in 10 cases of trigeminal neuralgia, 10 cases of radicular pain and in 14 blood donors. Only in the blood donors this level was normal, in the remaining cases it was statistically significantly decreased, especially in cases of radicular pains. The author believes that in the period of Horton's headaches the testosterone level is decreased due to recurrent attacks of pain and not due to a process involving the hypothalamus.
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PMID:[Blood testosterone levels in patients with Horton's headache]. 664 28

A 47-year-old woman had been suffering for 6 years from attacks of the most severe headaches lasting 4 to 6 days and occurring once or twice a month. The principal clinical manifestations of the disorder permitted its qualification as migrainous neuralgia. A unique characteristic of regularly occurring cephalgic attacks consisted in the constant alternation of suddenly developing and equally rapid-disappearing algetic episodes lasting 25-40 sec with cephalgia-free periods of 20-25 seconds. In interictal periods, momentary fulgurant pains in the right half of the head occurred during sharp turns of the neck. The administration of indomethacin in a dose of 50-75 mg daily was followed by a dramatic therapeutic response. The case described was identical to cases of Horton's syndrome differentiated by Sjaastad and Dale as an individual disease entity called "chronic paroxysmal migrainous neuralgia".
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PMID:[Indomethacin-sensitive variant of migrainous neuralgia]. 666 56

Behavioral interventions shown to be clinically effective in the treatment of migraine headache have generally not been employed for cluster headache. Herein, we report on the treatment of a severe case of chronic cluster headache with a common method of migraine treatment, temporal blood volume pulse (BVP) biofeedback. The patient was a 61-year-old male, medically diagnosed as suffering from chronic cluster headaches for over 20 years. Following an 18-day baseline, 14 BVP biofeedback sessions were conducted over a 7-week period. By the last 2 weeks of treatment, there was a 70% reduction in daily headache frequency and a 45% decrease in headache severity. Improvement was maintained at 1, 3, 6, 12, and 21 months follow-up. Large decreases in the consumption of migraine abortives , narcotic analgesics, and antiemetics were also observed. These encouraging results call for further evaluation of the efficacy of BVP biofeedback treatment of chronic cluster headache.
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PMID:Blood volume pulse biofeedback treatment of chronic cluster headache. 667 28

The headache histories obtained from clinical interviews of 600 patients were analysed by computer to see whether patients could be separated systematically into clinical categories and to see whether sets of symptoms commonly reported together differed in distribution among the categories. The computer classification procedure assigned 537 patients to the same category as their clinical diagnosis, the majority of discrepancies between clinical and computer classifications involving common migraine, tension-vascular and tension headache. Cluster headache emerged as a clearly-definable syndrome, and neurological symptoms during headache were most prevalent in the classical migraine group. However, the classical migraine, common migraine, tension-vascular and tension headache categories differed in terms of the number, rather than the nature, of common migraine features. Whether the two extremes of this migraine-tension headache spectrum are different disorders can be determined only by studies of their pathophysiology.
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PMID:Clinical diagnosis and computer analysis of headache symptoms. 670 52

Cluster headache remains a disease with almost totally unknown etiology and poorly understood pathogenesis. Some evidence has been presented to suggest that histamine released from mast cells might possibly be responsible for the initiation of pain attack. The authors present ultrastructural data concerning cutaneous mast cells in the painful region in patients suffering from cluster headache. The biopsies were taken between attacks in a bout. The fine structure of the mast cells (namely swollen granules, zones of decreased density, membrane-bound vesicles and granular fusion) are consistent with the dissolution pattern of secretion. The possible role of antidromic-reflex activation of the mast cells is also discussed.
Cephalalgia 1984 Jun
PMID:Mast cells in cluster headache. Ultrastructure, release pattern and possible pathogenetic significance. 673 78

Anamnestic data and clinical features were accurately investigated in 180 patients with cluster headache; 161 were episodic sufferers and 19 were chronic. A significantly high familial incidence of coronary heart disease was found. The patients' medical history revealed a significantly high incidence of peptic ulcer disease and head injury with brain concussion. It is stressed that the side on which head injury took place is very frequently the same side on which cluster headache is located, although the latency between the two events appears to be a long one. The study of timing of cluster periods suggests, for some patients, a constant, typical temporal pattern not necessarily related to seasons or the months of of the year. Cluster attacks frequently occur during certain periods of the day (onset being most frequent between 1 and 3 p.m.). Cluster headache cannot be considered as a nocturnal headache.
Cephalalgia 1983 Mar
PMID:Cluster headache--clinical findings in 180 patients. 685 Aug 18

Serum levels of various hormones have been estimated in cluster headache and non-cluster headache controls. Cluster headache patients were studied prior to, during, and after attack. During the cluster phase, plasma testosterone levels were low, whereas levels were within the reference limits. Normal values were also found in control patients with non-cluster headache. It is suggested that a decrease of plasma testosterone levels in episodic cluster headache should be viewed in context with disordered REM sleep in cluster headache.
Cephalalgia 1983 Mar
PMID:Low plasma testosterone levels in cluster headache. 685 Aug 20

Eight definite and 10 possible cases of CPH are known to the authors. Decisive diagnostic features in the differential diagnosis versus ordinary cluster headache (Horton's headache) seem to be: the presence of headache every day, a high maximum daily attack frequency (greater than or equal to attacks/24 hours) and an absolute indomethacin effect. There is increasing evidence for a female preponderance in CPH. It emerges from this study that there frequently (or invariably?) is a pre-CPH stage with atypical attack pattern, usually lasting several years. Pregnancy seems to have a rather clear ameliorating effect on attack frequency and severity. In other patients, the very onset of headache is immediately after delivery. The importance of recognizing this special headache from a clinical point of view is clear since this disabling disorder can be completely abolished by drug therapy.
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PMID:Chronic paroxysmal hemicrania (CPH). The clinical manifestations. A review. 693 56

Present views on the cause and treatment of temporal arteritis, trigeminal neuralgia, pain arising from the neck, benign intracranial hypertension, and other headaches of intracranial origin are summarized. The clinical components of migraine are correlated with recent studies of cerebral blood flow, monoamine changes, and the platelet release reaction. Psychological, physiological, and pharmacological management is based on the holistic concept of migraine as an uninhibited protective reaction. Cluster headache is subdivided into three varieties which respond preferentially to different medication. Tension headache may depend more on vascular mechanisms than excessive muscle contraction, but treatment is still directed at behavioral management and relaxation training with the aid of antidepressant therapy.
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PMID:Headache. 702 51

Regional cerebral blood flow (rCBF) was measured using the intra-arterial 133Xe technique in 35 or 256 areas of a hemisphere. In seven patients rCBF was measured in the resting state and following intracarotid (i.c.) infusion of histamine 10-50 microgram/min. In four patients histamine was infused intravenously in a dose of 25-40 microgram/min. Histamine caused no significant change in mean arterial blood pressure or arterial PCO2. There was no significant change in mean hemispheric blood flow during i.v. or i.c. histamine infusion. No change in the regional distribution of hemispheric blood flow was observed. Experimental histamine headache is most likely of extracranial origin.
Cephalalgia 1982 Mar
PMID:Effect of histamine on regional cerebral blood flow in man. 711 37


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