Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0018681 (headache)
 56,091 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Pulmonary edema is the primary danger in cardiac patients who undergo abortion by intra-amniotic instillation of hypertonic saline solution. The intra-amniotic saline has not been considered safe for induction of abortion in the 2nd trimester of pregnancy due to either immediate or late complications. Side effects range from vomiting, diarrhea, and headaches to severe septicaemea, convulsions, hemorrhage, disseminated intra-vascular coagulation, and pulmonary edema. Pulmonary edema is often unanticipated in women with "tight" mitral stenosis which was unrecognized in pregnancy. Organic lesion in the heart is often undetected prior to instillation of hypertonic saline which could subsequently cause cardiac failure and lung edema.
 ...
PMID:Unanticipated complications of intra amniotic saline. 1233 31

60 outpatients who submitted to termination of pregnancy at less than 12 weeks gestation (legal abortion) were randomly anesthetized with fentanyl + thiopentone, ketamine + diazepam, thiopentone + halotane, or thiopentone + enflurane. Each patient breathed spontaneously 3 liters/minute of nitrous oxide. The psychomotor recovery time was evaluated by means of the Zazzo test of "deux barrages" and the matrix attentive test. The anesthesia time and the intra- and postoperative side effects were recorded too. There was a greater frequency of nausea, vomiting, headache, and postoperative restlessness in those patients anesthetized with ketamine + diazepam. This anesthetic mixture induced a longer psychomotor recovery time. On the other hand, in patients anesthetized with fentanyl + thipentone, the authors observed a need for intraoperative additional analgesia during dilatation of the cervix. On the contrary, either technique with the volatile anesthetic agents halothane or enflurane is satisfactory for outpatient termination of pregnancy. When compared with the total intravenous anesthetic technique, the use of enflurane resulted in swifter recovery and minimal side effects and proved to be a safe and reliable anesthetic for this procedure. (author's)
 ...
PMID:[Anesthesia for outpatient termination of pregnancy: a comparison of anesthetic techniques]. 1234 Sep 58

The leading cause of maternal mortality and morbidity in developing countries is the lack of cesarean section deliveries due to the tremendous logistical, cost, and training problems associated with this procedure. This article describes the need for raising cesarean section rates in developing countries and what can be done with existing inadequate health care in these countries to increase these rates. 5 to 10% of all births should be done by cesarean section, yet only 0.3% of births in rural Zaire are cesarean sections. To help educate health officials about women who may need a cesarean section, this article provides: 5 basic warning signs of pregnancy complications, characteristics of high risk women, and women in their 3rd trimester who need to be referred. Crucial factors that delay mothers from getting prenatal care include cultural obstacles and undereducated traditional birth attendants. Complication signs include severe vomiting, swelling of face, feet and hands, vaginal bleeding, headache and fever. High risk mothers are age 18 or 35 years, have had 5 or more previous births, and under 150 cm. in height, experienced an abortion or stillbirth with previous pregnancy or delivered by cesarean section, had previous cephalo-pelvic disproportion or in labor 12 hours, or has chronic medical problems. Third trimester women experiencing or developing hypertensive diseases, non-vertex presentation, severe anemia, multiple birth or antepartum bleeding should be referred to a health center where a cesarean can be done if necessary.
 ...
PMID:Cesarean section. 1234 92

Q-Fever is a worldwide zoonosis caused by Coxiella burnetti. C. burnetti is an obligate intracellular parasite. It lives in phagolysosome of the host cell. By its infection of the sensitive persons develops the acute noncharacteristic disease, which passes noncharacteristically, with the appearance of higher temperature, headache, fever, weakness of the organism or by the appearance of symptoms of the undifferentiated infection of the upper parties of the respiratory system. In the course of the infection is being developed the intersticial pneumonia, what is the reason of the infected hospitalization. Most often get sick the sheep, cows and goats, what showed also on our examined sample. In most animals the symptoms of this bacterial infection are not present, pass unobviously, and get turned out during their gravidity. The most important carriers of the causes of this disease on the domestic or wild animals are artropodes, in which within the kind is possible also the transvatial and transstadial transfer. The wild animals transfer the disease at the domestic ones, and people most often are infected by contact with these animals, their consuming of meat or milk or by contact with their secretions. Though, the most important way of getting infected of people is aerosol contaminated by the carrier as these bacteria for a long get kept in the contaminated dust, wool, animal skin, fur, straw and the excretions of the infected animals. In the illusorilly healthy and pregnant animals the bacteria are to be found in the fertile water, chorions, and placenta, that is C. burnetti becomes the cause of the premature birth or abortion in these animals. In this way comes to the bacterial contamination of the environment of the animal itself. The diagnosis of Q.-Fever is complement fixation test, indirect immunofluorescence assay (IFT) and enzyme immunoassay (EIA).
 ...
PMID:Q-fever, human and animal morbidity in some regions of Bosnia and Herzegovina, in 2000. 1237 56

Migraine is an episodic headache disorder that occurs in four percent of children, six percent of men, and 18 percent of women. Most women with migraine improve during pregnancy. Some women have their first attack during pregnancy. Migraine can recur postpartum; it can also begin at that time. Despite their drug use, migraineurs do not differ from nonmigraineurs in their incidence of miscarriages, toxemia, congenital anomalies or stillbirths. Drugs are commonly used during pregnancy and, although medication use should be limited, it is not absolutely contraindicated. Most drugs are not teratogenic. Adverse effects such as spontaneous abortion, developmental defects, and various postnatal effects depend on the dose and route of administration and the timing of the exposure relative to the period of fetal development. In migraine, the risk of status migrainosus to the fetus may be greater than the potential risk of the medication used to treat the mother. Nonpharmacologic treatment is the ideal solution; however, analgesics such as acetaminophen and opioids can be used on a limited basis. Preventive therapy is a last resort.
 ...
PMID:MIGRAINE AND PREGNANCY. 1245 99

A link between migraine with aura and cardiac right-to-left shunting has been previously reported. Abortion or decreased frequency of migraine with aura attacks after atrial septal defect closure has been reported in the literature. We report the first case of transformation of migraine with aura into a daily pattern after atrial septal defect closure. A 48-year-old male who had been suffering from rather infrequent attacks of migraine with sensory and visual aura underwent transcutaneous closure of an atrial septal defect. His migraine attacks changed into a daily pattern the day following the procedure and remained so for 6 months. This change in pattern may be related to a changed intra-atrial pressure after the closure or some other unknown factor.
Headache 2003 May
PMID:Transformation into daily migraine with aura following transcutaneous atrial septal defect closure. 1501 73

This was a double-blind randomized control study to evaluate the efficacy of cervical priming by nitric oxide donor before second-trimester induced abortion. One-hundred healthy women with a singleton pregnancy between 14 and 20 weeks of gestation were randomized into either 40 mg isosorbide mononitrate or placebo, given intravaginally 12 h before induction. This was followed by intravaginal misoprostol induction. The induction-abortion interval, abortion rate, side effects and the woman's acceptability of the priming agent were recorded. All women completed the study and there was no severe complication recorded. There was no significant difference in the induction-abortion interval and abortion rate between the two groups. Isosorbide mononitrate group reported significantly more side effects of headache. More than 90% of the women in both groups found the priming agent acceptable. The application of intravaginal nitric oxide donors prior to the prostaglandins induction did not significantly improve the second-trimester induced-abortion process.
 ...
PMID:A study of the efficacy of cervical ripening with nitric oxide donor versus placebo for cervical priming before second-trimester termination of pregnancy. 1457 90

Of the total women included in the study, 96 women chose to receive misoprostol 600 microg sublingually while 53 women received misoprostol 800 microg vaginally 36-48 h after receiving mifepristone 200 mg. Complete abortion occurred in 93 women (98.9%) in the sublingual and 51 women (96.2%) in the vaginal group (p = 0.27). The mean induction-to-abortion interval was 3.2 h (SD = 1.4) in the sublingual and 4.1 h (SD = 1.5) in the vaginal group (p = 0.02). The mean gestation at abortion in weeks was 7.1 (SD = 1.0) in the sublingual and 7.7 (SD = 1.3) in the vaginal group (p = 0.003). Women in the sublingual group experienced more vomiting (p = 0.03), diarrhea (p = 0.02) and unpleasant taste in their mouth (p = 0.0001) while those in the vaginal group experienced more headache (p = 0.002). Of women in the sublingual group, 77% were satisfied with the route of misoprostol administration compared to 68% in the vaginal group (p = 0.25). These findings now need to be assessed in the context of a randomized controlled trial.
 ...
PMID:A pilot study of mifepristone in combination with sublingual or vaginal misoprostol for medical termination of pregnancy up to 63 days gestation. 1463 36

Hughes' syndrome (the antiphospholipid syndrome (APS)) presents with recurrent thrombosis, recurrent miscarriage and neurological disease. The major pathogenic mechanism of the syndrome is vascular obstruction (both venous and arterial) due to hypercoagulability. Neurological manifestations are prominent and are often the dominant feature. Headache, migraine and cognitive dysfunction are common while other manifestations such as dementia, epilepsy, chorea, multiple sclerosis (MS), psychiatric disease, transverse myelitis, ocular syndromes, sensorineural hearing loss and movement disorders are also associated with the syndrome. Anticoagulation therapy (either aspirin or oral anticoagulants) can lead to significant improvement.
 ...
PMID:The antiphospholipid (Hughes') syndrome: changing the face of neurology. 1524 15

Migraine and TTH are primary headache disorders that occur commonly during pregnancy. Migraine sometimes occurs for the first time with pregnancy. The majority of migraineurs improve while pregnant; however, migraine often recurs post partum. Some disorders that produce, headache, such as stroke, cerebral venous thrombosis, eclampsia, and SAH, occur more frequently during pregnancy. Diagnostic testing serves to exclude organic causes of headache, to confirm the diagnosis, and to establish a baseline before treatment. If neurodiagnostic testing is indicated, the study that provides the most information with the least fetal risk is the study of choice. Drugs commonly are used during pregnancy despite insufficient knowledge about their effects on the growing fetus. Most drugs are not teratogenic. Adverse effects, such as spontaneous abortion, developmental defects, and various postnatal effects, depend on the dosage and route of administration and the timing of the exposure relative to the period of fetal development. Although medication use should be limited, it is not absolutely contraindicated in pregnancy. In migraine, the risk for status migrainosus may be greater than the potential risk of the medication used to treat the pregnant patient. Nonpharmacologic treatment is the ideal solution; however, analgesics, such as acetaminophen and narcotics, can be used ona limited basis. Preventive therapy is a last resort.
 ...
PMID:Headaches in pregnancy. 1547 64


<< Previous 1 2 3 4 5 6 7 8 9 10