Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0018133 (graft-versus-host disease)
 18,032 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
HLA 3447
Sep 1217
CD4 1063
cytokine 897
CD8 794
lymphoid 727
SCT 627
human leukocyte antigen 526
CD34 435
gut 409
MHC 405
IL-2 381
major histocompatibility complex 364
CD25 338
AML 299
HLA-A 281
IFN 271
granulocyte colony-stimulating factor 267
interferon 257
thymus 257
G-CSF 249
IL-10 240
Mol 236
CML 224
ALL 221
IFN-gamma 212
tumor necrosis factor 204
granulocyte 192
IL-4 192
interleukin-2 189
She 185
IL-6 184
B10 183
TNF 169
HLA-DR 159
MTX 158
CD28 155
severe combined immunodeficiency 147
DBA 146
TCR 146
DRB1 146
interferon-gamma 141
CR1 139
ABO 136
HLA class I 132
HA-1 128
human leucocyte antigen 127
CD19 124
T cell receptor 123
Fas 118
TNF-alpha 114
calcineurin inhibitor 111
IL-17 107
calcineurin 106
CSF 102
collagen 101
non-Hodgkin's lymphoma 99
FK506 98
lipopolysaccharide 98
MDS 96
CD56 93
chemokine 89
CR2 88
perforin 85
MHC class II 84
MHC class I 83
erythroid 78
CSA 77
HLA-C 77
NOD 76
MLC 74
CD80 71
IL-2 receptor 70
Cytokine 69
RIC 68
natural killer cell 68
DQB1 68
HLA-B 67
GM-CSF 66
interferon gamma 66
hemoglobin 64
Fas ligand 64
CD86 64
CD20 63
HLA class II 63
CD40 63
IL-15 62
IgA 62
tumor necrosis factor alpha 61
interleukin 2 60
HSC 59
thymidine kinase 59
NRM 58
CD62L 58
CD40L 58
HLA-DRB1 57
CD45 55
CD2 54
PHA 54
FOXP3 54
tyrosine kinase 53
CTLA-4 53
CD52 53
EFS 53
granzyme B 52
LPS 52
ICAM-1 51
CD5 51
IL-7 50
insulin 50
BCR 50
PD-1 50
HLA-DPB1 50
CD69 49
ABL 49
C-reactive protein 47
IL-1 47
MLR 45
albumin 45
interleukin-10 45
granulocyte-macrophage colony-stimulating factor 44
IgE 44
MSD 44
CD14 43
CD16 42
CD11c 42
THC 42
DPB1 42
IL-5 41
NHL 41
Y chromosome 41
interleukin-6 40
interleukin-2 receptor 40
KIR 40
lymphokine 40
CD127 40
erythropoietin 39
HLA-DP 39
Thy-1 39
TGF-beta 39
mTOR 39
reserved 39
ferritin 39
FasL 39
NKG2D 38
IL-8 38
indoleamine 2,3-dioxygenase 37
HLA-A2 37
interferon-alpha 36
CD44 36
adhesion molecule 36
IL-13 36
interleukin-4 35
CD11b 35
MSC 34
Tumor necrosis factor 34
SAA 33
NK1 33
CTLA4 33
CXCR3 32
more...
Disease
graft-versus-host disease 18032
leukemia 2597
cancer 2154
acute myeloid leukemia 1246
tumor 1023
cytomegalovirus 923
chronic myeloid leukemia 886
hematologic malignancies 823
aplastic anemia 755
acute lymphoblastic leukemia 722
myelodysplastic syndrome 673
lymphoma 663
SCT 627
Acute graft-versus-host disease 569
acute leukemia 485
multiple myeloma 386
Chronic GVHD 383
pneumonia 329
immunodeficiency 310
interstitial pneumonia 293
sepsis 273
neutropenia 263
Hodgkin's disease 251
Epstein 248
veno-occlusive disease 247
SCID 241
sepsis 234
rash 233
thrombocytopenia 212
Leukemia 208
anemia 208
minimal residual disease 201
systemic lupus erythematosus 193
virus infection 173
autoimmune disease 173
bronchiolitis 164
DBA 162
aspergillosis 161
fungal infection 160
thalassemia 152
infectious diseases 149
chronic lymphocytic leukemia 146
pancytopenia 145
hepatitis 145
non-Hodgkin's lymphoma 141
scleroderma 131
chronic lymphocytic leukemia 129
lupus 128
rheumatoid arthritis 124
Infection 116
Fanconi 113
Crohn's disease 111
cystitis 110
herpes simplex 107
diabetes 107
PSS 106
immune deficiency 105
colitis 104
sickle cell disease 103
Best 101
inflammatory bowel disease 96
MDS 96
lupus 96
viremia 95
influenza 92
HIV 91
multiple sclerosis 91
thalassemia major 89
hypertension 89
lichen planus 87
cutaneous T-cell lymphoma 86
suicide 86
liver disease 83
respiratory failure 80
blast crisis 80
CSA 77
lymphopenia 77
NOD 76
lymphoblastic leukemia 75
residual disease 75
MLC 74
myelofibrosis 74
psoriasis 73
AIDS 72
varicella 71
lymphoproliferative disorders 67
renal disease 66
renal failure 65
herpes 65
bacteremia 65
proteinuria 64
dermatitis 64
arthritis 63
glomerulonephritis 63
primary biliary cirrhosis 62
hepatic veno-occlusive disease 62
hepatitis B 60
encephalitis 59
opportunistic infection 59
B-cell lymphoma 58
encephalopathy 58
myelosuppression 56
skin disease 56
Infections 55
lung disease 55
Bronchiolitis obliterans 55
PHA 54
cirrhosis 53
bacterial infection 52
cholestasis 52
hemolytic anemia 51
Brown 51
myeloid leukemia 51
nephrotic syndrome 51
Wiskott-Aldrich syndrome 50
ABL 49
breast cancer 48
mantle cell lymphoma 48
hemoglobinopathies 47
eosinophilia 46
depression 46
squamous cell carcinoma 46
iron overload 46
vasculitis 46
tumor growth 46
hemophagocytic lymphohistiocytosis 45
melanoma 44
follicular lymphoma 44
MSD 44
stroke 44
ABO incompatibility 44
renal cell carcinoma 43
hepatitis C 43
polymyositis 43
chronic granulomatous disease 43
membranous nephropathy 43
carcinoma 42
MRD 41
NHL 41
hyperbilirubinemia 40
metastases 39
xerostomia 39
Spleen 39
ulcerative colitis 39
type 1 diabetes 38
plaque 38
solid tumor 38
neuroblastoma 37
myasthenia gravis 37
acute renal failure 37
myeloproliferative disorders 36
adult T-cell leukemia/lymphoma 36
asthma 35
thrombocytopenic purpura 35
sarcoma 35
tuberculosis 35
lupus nephritis 34
RAEB 34
myocardial infarction 33
heart failure 33
more...
Symptom
diarrhea 327
pain 90
splenomegaly 80
abdominal pain 63
erythema 63
dry eye 60
dyspnea 58
seizures 50
cough 45
fatigue 43
vomiting 41
nausea 41
weakness 33
hepatosplenomegaly 30
headache 27
respiratory distress 25
anorexia 25
discomfort 21
nausea and vomiting 20
discomfort 18
exhaustion 17
hepatomegaly 17
anesthesia 17
chills 16
cachexia 16
myalgia 15
overweight 13
bone pain 12
arthralgia 10
functional recovery 10
constipation 10
fever of unknown origin 9
shortness of breath 9
tremor 8
exertional dyspnea 8
wheezing 7
lethargy 7
hemoptysis 7
analgesia 7
photophobia 6
thinning 6
ataxia 6
abdominal cramps 6
chest pain 5
sleepiness 5
Ill 5
hypothermia 5
paresis 4
flushing 4
intestinal bleeding 4
mouth pain 4
dysarthria 4
paresthesia 4
skin damage 3
agitation 3
numbness 3
dizziness 3
emaciation 3
blurred vision 3
generalized erythema 3
collapse 3
insomnia 3
vertigo 3
hypoproteinemia 2
abdominal discomfort 2
Respiratory symptoms 2
bloating 2
non-productive cough 2
regurgitation 2
Gastrointestinal symptoms 2
persistent cough 2
dysesthesia 2
pallor 2
starvation 2
rales 2
leg edema 2
eye pain 2
memory loss 2
tachypnea 2
flank pain 2
Halo 2
dry skin 2
tonic-clonic seizure 2
asthenia 2
acidity 2
productive cough 2
epigastric pain 2
HSA 2
hemiplegia 2
acute abdominal pain 2
night sweats 2
hypotonia 2
consciousness disturbance 2
livedo 2
partial seizure 1
lightheadedness 1
microbial colonization 1
Flare 1
Neurologic symptoms 1
incoordination 1
Retrosternal pain 1
inanition 1
painful swallowing 1
leg pain 1
menopausal symptoms 1
swollen joints 1
vaginal pain 1
pleuritic chest pain 1
muscle cramps 1
onychomadesis 1
Skin thickening 1
cardiovascular impairment 1
No adverse effect 1
lassitude 1
tenesmus 1
snoring 1
chronic cough 1
rigors 1
clubbing 1
adenitis 1
abnormal breathing 1
myoclonus 1
skin pain 1
oliguria 1
loss of taste 1
dysuria 1
Fluctuation 1
body pain 1
right upper quadrant pain 1
angina 1
Mental status changes 1
facial pain 1
excessive sweating 1
syncope 1
auditory hallucination 1
fasciculation 1
pelvic pain 1
tingling 1
Severe diarrhea 1
low back pain 1
cerebellar ataxia 1
joint stiffness 1
clumsiness 1
stigma 1
hematocolpos 1
generalized rash 1
chest tightness 1
nasal congestion 1
neuromuscular manifestation 1
twitching 1
hypercapnia 1
Drug
IL-2 381
Dermatol 281
G-CSF 256
IFN-gamma 207
CSF 154
Campath 130
Campath 130
TRM 106
MDS 96
Tacrolimus 84
CTX 65
Antithymocyte globulin 44
Fludarabine 40
Rituximab 40
Posaconazole 29
Ganciclovir 18
Bortezomib 17
Imatinib 17
Filgrastim 16
CTX 15
CTX 15
lysine 14
Fluconazole 13
Daclizumab 13
Filgrastim 13
Cardiovasc 12
Infliximab 11
Infliximab 11
Acyclovir 11
KGF 11
Methylprednisolone 10
Basiliximab 9
Dial 9
Prednisone 9
Norplant 9
Basiliximab 9
ROC 8
MAP 8
Prednisolone 8
AmBisome 8
p75 8
Caspofungin 8
Lenalidomide 8
Tocilizumab 7
Mycophenolic acid 6
Monit 6
G418 6
MRC 6
Neoral 6
Ontak 6
Ontak 6
Maraviroc 6
IL-11 5
Orthoclone OKT3 5
Budesonide 5
anti-CD33 5
CAM 5
Vitamin A 5
CTC 5
Asthma 5
TAC 5
lactose 5
Dasatinib 5
PMEA 5
Leucovorin 5
CTC 5
Leaf 4
Retinoic acid 4
AraC 4
Micafungin 4
Hypaque 4
Vorinostat 4
Abatacept 4
Indomethacin 4
ascorbate 4
Gleevec 4
IFN-beta 4
Cidofovir 4
Hypaque 4
Nephron 3
Valganciclovir 3
Prograf 3
PDL 3
ARA-C 3
Clofarabine 3
Mizoribine 3
Albumin 3
Meth 3
Alliance 3
Etoposide 3
Lenograstim 3
Theophylline 3
ROS 3
PFA 3
Ipilimumab 3
Alefacept 3
Activin 3
IL-1ra 3
ACT 3
CCL 3
AMC 3
Bifidobacterium 2
Sorafenib 2
CTA 2
Itraconazole 2
Heme 2
Zoledronic acid 2
Histamine 2
MOF 2
SBT 2
Deferasirox 2
Orphan 2
Muromonab-CD3 2
Gel 2
ampicillin 2
Visilizumab 2
Serum albumin 2
Adenosine deaminase 2
Everolimus 2
Cremophor EL 2
Immune globulin 2
Coumadin 2
Busulfex 2
Fraction 2
caffeine 2
Trimethoprim-sulfamethoxazole 2
Isopaque 2
Imidan 2
Platelet concentrate 2
Giardiasis 2
Azithromycin 2
Belatacept 2
Nephron 2
Zoledronic acid 2
Ranitidine 1
Tirilazad mesylate 1
Fansidar 1
balanced salt solution 1
Repifermin 1
Gelatin 1
-deoxyadenosine 1
Xanthium 1
Sandostatin 1
Sodium valproate 1
MTC 1
Isoniazid 1
Riboflavin 1
Teduglutide 1
Aprotinin 1
MEPM 1
HPMPC 1
NovoSeven 1
GVG 1
Doyle 1
Xanthoxin 1
Roflumilast 1
Erlotinib 1
Gastro 1
Roquinimex 1
Eculizumab 1
more...
Enzyme
BMT 926
focal adhesion kinase 113
calcineurin 106
ERK 62
thymidine kinase 59
granzyme B 51
ricin 44
alanine aminotransferase 43
indoleamine 2,3-dioxygenase 36
lactate dehydrogenase 36
mitogen-activated protein kinase 33
aspartate aminotransferase 32
APC 30
proteasome 30
luciferase 24
peroxidase 22
reverse transcriptase 20
STR 19
alkaline phosphatase 19
Thy1 16
CD13 15
caspase-1 12
transcriptase 11
thrombin 11
RNA polymerase 11
adenosine deaminase 10
adenosine deaminase 10
caspase-3 10
AST 9
CD10 9
asparaginase 9
creatine kinase 8
gamma-glutamyl transpeptidase 8
thromboplastin 7
CYP3A4 7
TSP-1 7
acetylcholinesterase 7
protein kinase C 7
tissue plasminogen activator 6
protein kinase 6
caspase-9 5
catalase 5
methylenetetrahydrofolate reductase 5
RNase 5
thyroid peroxidase 5
P-glycoprotein 5
neuraminidase 5
methylenetetrahydrofolate reductase 5
MIP 5
MAP 5
RNase 5
collagenase 5
glutathione S-transferase 5
aldolase 5
alpha-L-iduronidase 5
caspase-8 4
cholinesterase 4
lysozyme 4
MEK 4
endonuclease 4
plasmin 4
ACS 4
MDR 4
aldehyde dehydrogenase 4
BAL 4
NO synthase 4
trypsin 4
lipase 4
IMP dehydrogenase 4
cdc2 4
ACE 3
renin 3
PCE 3
beta-galactosidase 3
acid phosphatase 3
UDP-glucuronosyltransferase 3
sulfatase 3
purine nucleoside phosphorylase 3
phosphoinositide 3-kinase 3
phosphatidylinositol 3-kinase 3
elastase 3
NADPH oxidase 3
myosin light chain kinase 3
ATPase 3
phosphorylase 3
NADPH oxidase 3
AMPK 2
HDR 2
dihydrofolate reductase 2
chitinase 2
Rex 2
beta-glucuronidase 2
PAM 2
pepsin 2
carbonic anhydrase 2
PNGase F 2
arginase 2
phosphodiesterase 2
lecithin:cholesterol acyltransferase 2
furin 2
proteinase-3 2
aldehyde dehydrogenase 2
arylsulfatase 2
aldehyde dehydrogenase 2
aldehyde dehydrogenase 2
PARP 2
phosphoglucose isomerase 2
TdT 2
cathepsin S 2
thymidine phosphorylase 2
aldehyde dehydrogenase 2
dipeptidyl peptidase IV 2
lactase 2
legumain 2
MMP-3 2
DNA methyltransferase 2
ceruloplasmin 2
DTA 2
superoxide dismutase 2
heme oxygenase 2
alpha-L-fucosidase 2
caspase-7 1
ribonuclease 1
caspase-11 1
tryptase 1
LasR 1
tryptophanase 1
AMP-activated kinase 1
ATP synthase 1
caspase-7 1
AMP-activated protein kinase 1
prenyltransferase 1
topoisomerase 1
histone-lysine N-methyltransferase 1
thymidylate synthase 1
caspase-2 1
adenylate cyclase 1
AOR 1
caspase-11 1
N-acetyltransferase 1
peptide-transporting ATPase 1
phosphoglycerate kinase 1
CEP 1
glyceraldehyde-3-phosphate dehydrogenase 1
CEP 1
phospholipase C 1
inositol phosphatase 1
DAT 1
granzyme M 1
glutathione peroxidase 1
DSR 1
iduronate-2-sulfatase 1
DNA ligase 1
DNA ligase 1
PRT 1
guanase 1
BMA 1
arylsulfatase A 1
cyclohydrolase 1
IKK 1
more...
Compound
Dec 1340
Clin 1144
DNA 509
TBI 271
Cyclosporine 228
Methotrexate 213
FK506 180
TNF 169
MTX 159
DBA 146
DBA 146
DBA 146
creatinine 97
His 73
CTX 65
oxygen 61
iron 51
BCR 50
ABL 49
Rapamycin 46
Neo 46
DFS 45
TMA 43
Busulfan 43
TMA 43
Mycophenolate mofetil 42
calcium 42
Ara-C 42
NKT 41
Ara-C 41
phosphate 40
glucose 38
Optimal 38
VP-16 33
leucine 32
DLA 31
nitric oxide 31
potassium 29
sodium 29
tryptophan 28
acetate 28
retinoic acid 25
tryptophan 25
tyrosine 25
nitrogen 25
tryptophan 24
ACI 24
sulfate 24
tryptophan 24
vitamin D 22
Voriconazole 21
arginine 20
ATP 20
water 20
folinic acid 18
ECP 17
ECP 17
ECP 17
Isoproterenol 16
CO2 16
Vitamin D 16
lysine 16
cysteine 15
Pac 15
urea 15
diacetate 14
PEG 14
DHB 14
Interleukin-2 13
GM1 13
glutamine 13
alanine 13
serine 13
hydrogen 12
6-12 12
GMP 12
TMP 11
TMP 11
TMP 11
TMP 11
L-PAM 11
Acyclovir 11
PGE2 11
L-PAM 11
neopterin 10
PEG 10
Psoralen 10
BMC 10
BCNU 10
Methylprednisolone 10
CIT 9
A 3 9
Prednisone 9
methionine 9
Ursodeoxycholic acid 9
valine 9
8-MOP 9
A 1 9
Dial 9
uridine 9
Lewis X 9
Prednisolone 8
copper 8
MAP 8
SDS 8
AMP 8
L-leucine 8
MOP 8
Deoxycoformycin 8
PMA 8
nitrate 8
iodine 8
Parenteral 8
Etanercept 7
PMA 7
NADP 7
DBM 7
AAT 7
H2O2 7
TTP 7
DRB 7
chromium 7
glutamic acid 7
barium 7
5-Azacytidine 7
GSH 7
Thiotepa 7
MIC 7
GSH 7
silver 7
Nitrite 7
nicotinamide 7
TOF 7
retinol 6
A 42 6
zinc 6
DMSO 6
Phe 6
MMA 6
Hydroxychloroquine 6
DBM 6
salt 6
LTC4 6
NMA 6
threonine 6
MSG 6
SCN 5
Gliotoxin 5
EDTA 5
Gliotoxin 5
Amphotericin B 5
Vitamin A 5
proline 5
ALP 5
Cyt 5
ammonium 5
cAMP 5
xylose 5
MTT 5
dUTP 5
more...