Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0018099 (gout)
 5,192 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

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Human Gene/Protein
transmembrane protein 85 12.6
HPRT1 protein 12.6
ALDH16A1 12.1
FJHN 11.9
EIF1AD 11.6
LRRC16A 11.3
SLC17A3 11.2
SLC2A9 11.1
SLC22A12 11.0
HLA-B associated transcript 3 11.0
platelet receptor for type III collagen 11.0
SYTL5 11.0
NRBP1 11.0
SLC16A9 10.6
GLUT9 10.6
NIPAL1 10.6
MHC class I polypeptide-related sequence B 10.6
ERO1LB 10.6
ZNF518B 10.6
SLC17A2 10.6
SLC22A11 10.5
SLC17A4 10.4
PAP39 10.4
INHBC 10.3
HLA-B*5801 10.3
PAP41 10.3
OHCU decarboxylase 10.3
NPT1 10.2
FAM35A 10.1
PRPS1 10.1
A1CF 10.1
urate transporter 1 10.0
B3GNT4 10.0
TRIM46 10.0
ORCTL3 10.0
FRMD8 10.0
mitochondrial ribosomal protein S7 10.0
organic anion transporter 4 9.9
HNF4G 9.9
Phosphoribosyl pyrophosphate synthetase 9.8
guanine aminohydrolase 9.8
UBE2Q2 9.7
RST 9.7
sodium phosphate transporter 9.6
CNIH2 9.6
NPT4 9.6
alpha-kinase 1 9.6
NALP2 9.6
uromodulin 9.4
TM4SF4 9.4
SYT7 9.4
NAP1L5 9.3
calcitonin 2 9.3
RNF139 9.3
SMCT2 9.3
MXD3 9.3
otopetrin 1 9.3
SLC9A2 9.3
RFX3 9.2
CMTX5 9.1
anion transporter 1 9.1
BCAS3 9.1
OAT4 9.1
CUX2 9.1
hypoxanthine guanine phosphoribosyltransferase 9.0
ENTPD5 9.0
PRS2 8.8
PRS I 8.8
prostaglandin reductase 2 8.8
ALPK1 8.8
xanthine oxidoreductase 8.6
human leukocyte antigen B 8.6
GSD1a 8.6
MSU 8.5
OAT7 8.5
PRPS2 8.5
CNIH 8.5
PSORS1C1 8.3
CAP70 8.3
kinesin family member 3A 8.3
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Disease
Periarthritis calcarea 12.6
Hyperuricemic nephropathy 12.6
Hyperostotic spondylosis 12.6
Secondary gout 12.6
Acute lead nephropathy 12.6
Gout flare 12.6
gout 12.6
tophi 12.4
Chronic tophaceous gout 12.2
FJHN 11.9
Gouty arthritis 11.9
Acute gouty arthritis 11.8
Kelley-Seegmiller syndrome 11.7
podagra 11.7
crystal arthropathy 11.6
Chronic lead nephropathy 11.6
Chronic gouty arthritis 11.6
Visceral gout 11.3
pseudogout 11.2
gouty nephropathy 11.2
hyperuricemia 10.9
MCKD2 10.6
Achilles tendon thickening 10.3
arthritis deformans 10.3
Bicipital tendinitis 10.3
MCKD1 10.3
infected ingrown toenail 10.3
Pneumococcal arthritis 10.3
Ulnar tunnel syndrome 10.0
Uric acid nephrolithiasis 10.0
chondrocalcinosis 9.9
acute arthritis 9.8
SLE arthritis 9.8
Pyrophosphate arthropathy 9.8
FIHP 9.8
purine metabolism disorder 9.8
prepatellar bursa 9.8
Milwaukee shoulder 9.8
polyarthrosis 9.8
Acute synovitis 9.8
Milwaukee shoulder 9.7
Oxalate nephropathy 9.6
toxic amblyopia 9.6
Proximal myopathy 9.6
Bouchard's nodes 9.6
uricosuria 9.5
DFN2 9.4
CMTX5 9.3
Poultry Diseases 9.3
Drug-induced myopathy 9.3
chronic tracheitis 9.1
migratory arthritis 9.1
shoulder capsulitis 9.1
Rheumatoid nodulosis 9.0
humeroscapular periarthritis 9.0
Infectious crystalline keratopathy 9.0
periarthritis 9.0
Septic bursitis 8.9
Acute myopathy 8.9
Carpal collapse 8.8
Myoadenylate deaminase deficiency 8.8
sesamoiditis 8.7
Lesch-Nyhan syndrome 8.7
Lofgren's syndrome 8.7
ethanolism 8.7
Fibro-osseous pseudotumor 8.7
monoarthritis 8.6
Tokelau 8.6
infectious arthritis 8.6
algoneurodystrophy 8.6
fructosuria 8.6
hydroxyapatite deposition 8.5
Fanconi-like syndrome 8.4
Stenosing tenosynovitis 8.3
pyorrhea 8.3
cervicobrachial syndrome 8.2
NPHP1 8.1
cheilosis 8.1
osteochondromatosis 8.1
palindromic rheumatism 8.0
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Symptom
toe pain 9.1
Night pain 9.0
Foot pain 8.0
Soft stools 8.0
ischuria 7.9
vaginal itching 7.5
Sudden deafness 7.5
finger pain 7.4
musculoskeletal disability 7.1
renal colic 6.6
leg cramps 6.4
swollen joints 6.1
sciatica 6.0
elbow pain 5.9
localized edema 5.8
ankle pain 5.8
cardiovascular impairment 5.8
polymyalgia 5.7
ACHE 5.7
heel pain 5.7
arthralgia 5.5
wrist pain 5.4
generalized rash 5.4
loin pain 5.2
knee pain 5.2
metatarsalgia 5.1
prostration 5.0
catarrh 5.0
disturbed balance 4.7
Multimorbidity 4.7
stomach pain 4.6
chronic back pain 4.6
arm pain 4.6
polyuria 4.6
athetosis 4.5
acute low back pain 4.5
neck pain 4.4
adenitis 4.4
neuralgia 4.4
hip pain 4.4
dental pain 4.3
back pain 4.3
dysuria 4.3
dysesthesia 4.3
thirsty 4.3
acute pain 4.2
low back pain 4.1
flank pain 4.1
oliguria 4.1
Tenderness 4.0
groin pain 4.0
decreased appetite 4.0
night sweats 3.9
numbness 3.8
myalgia 3.8
muscle cramps 3.8
colic 3.8
hepatomegaly 3.7
erythema 3.7
emaciation 3.5
abdominal cramps 3.5
Decreased activity 3.5
hyperemesis gravidarum 3.5
Anoxia 3.5
shoulder pain 3.5
overweight 3.5
hypoproteinemia 3.4
hemiplegia 3.4
mental fatigue 3.4
pleuritic chest pain 3.4
Wind 3.2
thigh pain 3.2
limb pain 3.2
forgetfulness 3.2
fever of unknown origin 3.1
heartburn 3.1
pain 3.1
chest tightness 3.0
enuresis 2.9
consciousness disturbance 2.9
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Drug
Mifobate 12.6
Febuxostat 11.6
Polycillin-PRB 11.6
Rilonacept 10.6
C18H16N4 10.3
Y-700 10.1
Immucillin-G 9.6
Rasburicase 9.6
Lemon oil 9.3
Rasburicase 9.1
Feprazone 8.9
Acemetacin 8.5
Glatiramer Acetate 8.4
Bendrofluazide 8.2
Meclomen 8.0
Anakinra 7.9
Potassium citrate 7.9
TMX 7.9
Adenosine Monophosphate 7.7
Fenoprofen 7.7
Meclomen 7.6
Pirprofen 7.5
Feldene 7.4
Indoprofen 7.3
Fenbufen 7.1
Piretanide 6.9
Tenoxicam 6.6
Etodolac 6.6
Flunixin 6.6
Avonex 6.4
Compound 19 6.1
IL-1ra 5.5
Myricetin 5.3
Copaxone 5.3
Tranilast 4.9
Bumetanide 4.9
Tocilizumab 4.9
Aztec 4.8
Fructose 4.7
Voltaren 4.6
Aliskiren 4.6
Orphan 4.5
Guanethidine 4.5
Sucralfate 4.5
Ketotifen 4.4
Nimesulide 4.4
Coumadin 4.2
Felodipine 4.1
Orlistat 4.0
Hydrochlorothiazide 4.0
CTT 3.9
Cilostazol 3.9
Diclofenac sodium 3.8
ddI 3.8
Adenosine triphosphate 3.8
Rosuvastatin 3.8
Troglitazone 3.5
Misoprostol 3.5
Papain 3.5
Clofibrate 3.4
Digitalis 3.3
Rutin 3.2
Nephron 3.2
Adenosine deaminase 3.2
Camp 3.1
Riboflavin 3.0
CIA 3.0
AGG 3.0
Activin 2.8
Indomethacin 2.8
niacin 2.7
Isoniazid 2.7
Itraconazole 2.6
Nephron 2.6
Reserpine 2.6
ADR 2.6
Ketoconazole 2.5
FLP 2.5
ascorbate 2.4
Aloe 2.3
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Enzyme
PuuD 11.6
ureidoglycolate hydrolase 9.6
PRPP synthetase 9.5
uricase 9.4
ureidoglycolate lyase 8.2
xanthine oxidase 8.0
allantoicase 7.7
5'-methylthioadenosine nucleosidase 7.5
guanase 7.5
xanthine dehydrogenase 7.4
hypoxanthine-guanine phosphoribosyltransferase 7.1
adenine deaminase 6.9
GMP reductase 6.8
adenine phosphoribosyltransferase 6.7
amidophosphoribosyltransferase 6.7
allantoinase 6.6
caspase-5 6.4
caspase-5 6.1
adenylosuccinate lyase 6.0
caspase-1 6.0
cathepsin X 5.4
purine nucleoside phosphorylase 5.3
orotidine-5'-phosphate decarboxylase 5.2
orotate phosphoribosyltransferase 5.2
sarcosine oxidase 5.1
caspase-11 5.1
caspase-11 5.1
ornithine aminotransferase 5.1
aldehyde oxidase 5.1
17beta-HSD 4.9
adenylosuccinate synthetase 4.9
glutamic dehydrogenase 4.8
AMP deaminase 4.7
Hageman factor 4.6
17beta-HSD 4.2
peptidylarginine deiminase 4.1
caspase-4 4.1
fructokinase 4.1
methylmalonyl-CoA mutase 3.9
caspase-4 3.9
choline oxidase 3.9
glucose-6-phosphatase 3.8
sulfite oxidase 3.8
ALDH 3.8
NPL 3.7
lactic acid dehydrogenase 3.7
adenosine kinase 3.7
sulfite oxidase 3.7
lactic acid dehydrogenase 3.7
dihydroorotate dehydrogenase 3.6
dihydroorotate dehydrogenase 3.6
HK2 3.5
aldehyde dehydrogenase 3.4
1-hydroxylase 3.4
prostaglandin synthetase 3.3
mu-calpain 3.2
argininosuccinate synthetase 3.2
GCA 3.1
alanine aminopeptidase 3.1
lactic acid dehydrogenase 3.0
neutrophil elastase 2.9
cathepsin B 2.9
tryptophan 2,3-dioxygenase 2.8
aldehyde dehydrogenase 2.8
aldehyde dehydrogenase 2.8
aldehyde dehydrogenase 2.8
p100 2.8
Pla 2.8
CYP3A4 2.8
IMP dehydrogenase 2.8
cathepsin K 2.7
aldehyde dehydrogenase 2.7
adenosine deaminase 2.6
lysin 2.6
15-lipoxygenase 2.4
lecithin:cholesterol acyltransferase 2.3
adenosine deaminase 2.3
elastase 2.2
asparaginase 2.2
indoleamine 2,3-dioxygenase 2.1
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Compound
Colchizin 12.6
C22H25NO6 11.6
2-hydroxy-6-pentadecylbenzoic acid 11.6
C22H25NO6 11.6
Benzbromarone 11.0
Isocolchicine 11.0
C22H25NO6 11.0
C14H11NO2 11.0
APTP 10.6
Luteolin 7-O-glucoside 10.6
Benziodarone 10.6
Potassium oxonate 10.0
Oxypurinol 9.8
Uric acid 9.8
Allocolchicine 9.8
Thiocolchicine 9.8
Cinchophen 9.6
Oosporein 9.6
beta-Lumicolchicine 9.4
Scopolin 9.4
Budlein A 9.4
HPP 9.4
2-C-methyl-D-erythritol-2,4-cyclodiphosphate 9.3
Inosinic acid 9.3
2-phenyl-1H-imidazole 9.3
Budlein A 9.1
Perezone 9.1
C30H50 9.1
Benzarone 9.1
Murexide 9.0
Murexide 8.9
Tienilic acid 8.9
Eupatorin 8.8
Colchicine 8.7
C6H8O4 8.7
2-(1-piperidinyl)ethyl 8.6
Meclofenamate sodium 8.6
Etoricoxib 8.5
Orotidine 8.5
Azapropazone 8.4
Eupafolin 8.3
Probenecid 8.1
Fenoprofen 7.9
PRPP 7.6
Wedelolactone 7.5
Amiodarone hydrochloride 7.4
Polygodial 7.3
Salvarsan 7.3
4-chlorobenzaldehyde 7.3
4-chlorobenzaldehyde 7.3
4-chlorobenzaldehyde 7.3
4-chlorobenzaldehyde 7.3
Allantoin 7.3
4-chlorobenzaldehyde 7.3
4-chlorobenzaldehyde 7.3
4-chlorobenzaldehyde 7.3
4-chlorobenzaldehyde 7.3
Allantoin 7.3
Xanthine 7.3
4-chlorobenzaldehyde 7.3
Novex 7.3
4-chlorobenzaldehyde 7.3
Muramic acid 7.2
Salicin 7.2
Salicin 7.2
Lumicolchicine 7.1
Thiazide 6.9
Tolmetin 6.8
Purine 6.8
Anacardic acid 6.7
Sulfinpyrazone 6.7
3-hydroxyoctanoic acid 6.7
4-chlorobenzaldehyde 6.7
Suprofen 6.6
Hypoxanthine 6.6
Phloroglucinol 6.5
Phenylbutazone 6.3
Pyrazinamide 6.3
Rofecoxib 6.1
Dioscin 6.0
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