Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0018099 (gout)
5,192 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein xanthine oxidase 380 Sep 326 ankylosing spondylitis 106 cytokine 98 insulin 89 NLRP3 88 Mol 81 ABCG2 75 IL-1 74 hypoxanthine-guanine phosphoribosyltransferase 72 chronic renal failure 70 TNF 56 MRI 55 ATP 50 RST 47 SLC2A9 45 C-reactive protein 44 uromodulin 43 IL-6 41 IL-8 38 IL-18 36 HPRT 35 tumor necrosis factor 32 xanthine oxidoreductase 32 collagen 32 SLC22A12 30 AII 30 gut 30 pyrin 30 MSU 27 Mal 26 GLUT9 26 lipopolysaccharide 26 NALP3 26 NOD 25 rheumatoid factor 25 albumin 25 She 24 HDL 24 hemoglobin 24 CRP 22 X-linked 22 NMR 21 proximal tubule 21 renin 20 TLR4 18 ATP-binding cassette 17 chemokine 17 AMP 17 THP 17 COX-2 16 BCRP 16 IL-10 16 hemochromatosis 16 HLA 15 urate transporter 1 15 ASC 14 hypoxanthine guanine phosphoribosyltransferase 14 cyclooxygenase-2 14 Caspase-1 13 Pol 13 ACR 13 endoplasmic reticulum 13 catalase 13 PEG 13 JAMA 13 TOF 13 OAT1 12 LPS 12 glucose transporter 12 xanthine dehydrogenase 12 Men 12 asymmetrical 12 cytochrome P450 12 anion exchanger 11 NPT1 11 purine nucleoside phosphorylase 11 alkaline phosphatase 11 IgA 11 ROS 11 more...

Disease gout 5192 hyperuricemia 1159 arthritis 1107 hypertension 555 rheumatoid arthritis 529 diabetes 455 tophi 420 osteoarthritis 336 obesity 272 renal disease 268 arthropathy 188 metabolic syndrome 172 cardiovascular disease 163 cancer 160 pseudogout 150 systemic lupus erythematosus 145 renal failure 128 type 2 diabetes 122 ankylosing spondylitis 113 rheumatism 110 septic arthritis 104 atherosclerosis 104 renal insufficiency 103 chondrocalcinosis 102 chronic renal failure 87 psoriatic arthritis 87 tumor 83 hyperlipidemia 83 renal impairment 77 synovitis 76 heart failure 75 psoriasis 74 urolithiasis 70 nephrolithiasis 64 stroke 64 Gouty arthritis 63 polyarthritis 62 acute arthritis 61 coronary heart disease 59 familial Mediterranean fever 58 Lesch-Nyhan syndrome 58 dyslipidemia 57 osteoporosis 54 tuberculosis 51 depression 50 metabolic disorder 50 myocardial infarction 50 asthma 50 coronary artery disease 46 hyperparathyroidism 46 tenosynovitis 45 sepsis 40 infectious diseases 39 congestive heart failure 39 anemia 39 lupus 39 sepsis 38 proteinuria 37 bursitis 37 vasculitis 37 fibromyalgia 36 carpal tunnel syndrome 35 hepatitis 34 Alzheimer's disease 34 nephritis 34 podagra 33 monoarthritis 33 chronic disease 33 lupus 32 Reiter's syndrome 32 myocardial ischemia 31 amyloidosis 31 osteomyelitis 30 multiple sclerosis 29 alcoholism 28 rash 28 maple syrup urine disease 27 hypercholesterolemia 27 acute renal failure 26 scleroderma 25 more...

Symptom pain 371 arthralgia 54 overweight 47 weakness 44 diarrhea 42 back pain 40 low back pain 28 erythema 27 headache 26 angina 23 vomiting 20 nausea 18 abdominal pain 17 knee pain 17 sciatica 16 fatigue 15 myalgia 15 neck pain 14 renal colic 13 discomfort 12 numbness 12 polyuria 12 acute pain 12 hepatomegaly 12 discomfort 12 dyspnea 10 analgesia 10 anorexia 10 cough 9 seizures 9 dizziness 9 collapse 9 dysuria 8 constipation 8 anesthesia 8 colic 7 hemiplegia 7 flank pain 6 ataxia 6 hip pain 6 wrist pain 6 splenomegaly 6 swollen joints 6 neuralgia 6 lethargy 6 tremor 6 acidity 5 flushing 5 spasticity 5 shoulder pain 5 oliguria 5 hypotonia 5 ankle pain 5 paresthesia 5 chills 5 Wind 4 heel pain 4 dystonia 4 thinning 4 shortness of breath 4 stigma 4 paresis 4 starvation 4 sleepiness 4 dental pain 4 functional recovery 3 fever of unknown origin 3 elbow pain 3 dry eye 3 respiratory distress 3 night sweats 3 decreased appetite 3 vertigo 3 hoarseness 3 hepatosplenomegaly 3 Ill 3 chronic back pain 3 dysarthria 3 dysesthesia 3 hemoptysis 3 more...

Drug Febuxostat 74 Dermatol 45 Rasburicase 31 ascorbate 20 Nephron 18 Nephron 18 Cardiovasc 17 caffeine 12 ROS 11 IL-1ra 10 Anakinra 10 Dial 9 lysine 9 Rasburicase 8 Fructose 8 Indomethacin 7 CSF 7 Leaf 4 Monit 4 niacin 4 vitamin E 4 Rilonacept 4 G-CSF 3 TMX 3 lactose 3 IL-2 3 ABC 3 Bifidobacterium 3 ENT 3 Adenosine triphosphate 2 Fenoprofen 2 citric acid 2 Myricetin 2 Avonex 2 Etodolac 2 Ethanol 2 Albumin 2 Y-700 2 IFN-gamma 2 Tenoxicam 2 ampicillin 2 nitroglycerin 2 PTH 2 ADR 2 Activin 2 Copaxone 2 Tocilizumab 2 Orphan 2 Itraconazole 2 Glutathione 2 Potassium citrate 2 Spectrum 2 Bumetanide 2 Acemetacin 2 Bayer 1 Meclomen 1 Aztec 1 Hydrochlorothiazide 1 Feldene 1 Compound 19 1 Rutin 1 balanced salt solution 1 Digitalis 1 Sucralfate 1 NBT 1 Immucillin-G 1 Nimesulide 1 CDP 1 Fluorescein 1 Riboflavin 1 EPI 1 CIA 1 Adenosine Monophosphate 1 ddI 1 Piretanide 1 Aliskiren 1 Polycillin-PRB 1 ROC 1 ADM 1 NAG 1 more...

Enzyme xanthine oxidase 361 uricase 132 caspase-1 65 hypoxanthine-guanine phosphoribosyltransferase 56 xanthine dehydrogenase 35 PRPP synthetase 28 renin 20 peroxidase 17 catalase 14 mitogen-activated protein kinase 13 creatine kinase 13 ERK 12 alanine aminotransferase 12 aspartate aminotransferase 12 adenine phosphoribosyltransferase 12 alkaline phosphatase 11 ACE 11 superoxide dismutase 11 purine nucleoside phosphorylase 9 aldehyde dehydrogenase 9 ATPase 9 ACS 9 focal adhesion kinase 7 P-glycoprotein 7 elastase 7 NADPH oxidase 7 CYP3A4 7 glucose-6-phosphatase 7 lactate dehydrogenase 7 guanase 7 aldehyde dehydrogenase 7 calcineurin 7 NADPH oxidase 7 proteasome 6 collagenase 6 glutathione reductase 5 aldehyde dehydrogenase 5 aldehyde dehydrogenase 5 DNase 5 beta-glucuronidase 5 cathepsin B 5 aldehyde dehydrogenase 5 reverse transcriptase 5 gamma-glutamyl transpeptidase 5 adenosine deaminase 5 glutathione peroxidase 5 neutrophil elastase 5 aldehyde oxidase 4 caspase-3 4 adenosine deaminase 4 phospholipase A2 4 ornithine aminotransferase 4 thromboplastin 4 urease 4 lipoxygenase 4 trypsin 4 protein kinase C 4 urease 3 RNase 3 prostaglandin synthetase 3 AMP deaminase 3 lipoprotein lipase 3 urokinase-type plasminogen activator 3 NO synthase 3 acid phosphatase 3 IKK 3 adenylate cyclase 3 RNase 3 allantoicase 2 caspase-11 2 phosphatidylinositol 3-kinase 2 monoamine oxidase 2 orotidine-5'-phosphate decarboxylase 2 allantoinase 2 amidophosphoribosyltransferase 2 orotate phosphoribosyltransferase 2 GSK 2 arginase 2 ALDH 2 lysozyme 2 more...

Compound Clin 638 Dec 359 calcium 265 Uric acid 206 creatinine 187 HPP 155 Colchicine 140 sodium 112 glucose 111 potassium 95 oxygen 88 water 87 DNA 69 phosphate 68 TNF 56 His 55 ethanol 55 ATP 50 urea 45 nitrogen 36 hydrogen 35 salt 32 acetate 31 Probenecid 27 pyrimidine 26 PEG 26 pyrimidine 26 nitric oxide 25 oxalate 24 Benzbromarone 24 iron 24 methanol 21 EDTA 21 EDTA 21 ammonium 19 Cardiol 19 molybdenum 18 THP 17 THP 17 Purine 17 PEG 16 arginine 16 cysteine 15 ethyl acetate 15 DPPH 15 Pac 14 ASC 14 galactose 13 leucine 13 acetonitrile 13 tyrosine 13 TOF 13 copper 12 lysine 12 iodine 12 GMP 12 caffeine 12 vitamin D 11 Oxypurinol 11 H2O2 11 acetic acid 11 serine 11 phosphorus 10 IMP 10 Dial 10 Asp 9 zinc 9 Phe 9 ACS 9 ACS 9 Optimal 9 Xanthine 9 formic acid 8 aluminum 8 ADP 8 formic acid 8 Thiazide 8 GSH 8 ammonia 8 formic acid 8 more...

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