Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

---

Query: UMLS:C0018099 (gout)
5,192 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein xanthine oxidase 380 Sep 326 ankylosing spondylitis 106 cytokine 98 insulin 89 NLRP3 88 Mol 81 ABCG2 75 IL-1 74 hypoxanthine-guanine phosphoribosyltransferase 72 chronic renal failure 70 TNF 56 MRI 55 ATP 50 RST 47 SLC2A9 45 C-reactive protein 44 uromodulin 43 IL-6 41 IL-8 38 IL-18 36 HPRT 35 tumor necrosis factor 32 xanthine oxidoreductase 32 collagen 32 gut 30 SLC22A12 30 pyrin 30 AII 30 MSU 27 lipopolysaccharide 26 NALP3 26 Mal 26 GLUT9 26 NOD 25 albumin 25 rheumatoid factor 25 She 24 HDL 24 hemoglobin 24 more...

Disease gout 5192 hyperuricemia 1159 arthritis 1107 hypertension 555 rheumatoid arthritis 529 diabetes 455 tophi 420 osteoarthritis 336 obesity 272 renal disease 268 arthropathy 188 metabolic syndrome 172 cardiovascular disease 163 cancer 160 pseudogout 150 systemic lupus erythematosus 145 renal failure 128 type 2 diabetes 122 ankylosing spondylitis 113 rheumatism 110 atherosclerosis 104 septic arthritis 104 renal insufficiency 103 chondrocalcinosis 102 psoriatic arthritis 87 chronic renal failure 87 tumor 83 hyperlipidemia 83 renal impairment 77 synovitis 76 heart failure 75 psoriasis 74 urolithiasis 70 stroke 64 nephrolithiasis 64 Gouty arthritis 63 polyarthritis 62 acute arthritis 61 coronary heart disease 59 familial Mediterranean fever 58 more...

Symptom pain 371 arthralgia 54 overweight 47 weakness 44 diarrhea 42 back pain 40 low back pain 28 erythema 27 headache 26 angina 23 vomiting 20 nausea 18 abdominal pain 17 knee pain 17 sciatica 16 myalgia 15 fatigue 15 neck pain 14 renal colic 13 numbness 12 hepatomegaly 12 discomfort 12 acute pain 12 discomfort 12 polyuria 12 anorexia 10 dyspnea 10 analgesia 10 seizures 9 cough 9 collapse 9 dizziness 9 anesthesia 8 constipation 8 dysuria 8 hemiplegia 7 colic 7 hip pain 6 wrist pain 6 ataxia 6 more...

Drug Febuxostat 74 Dermatol 45 Rasburicase 31 ascorbate 20 Nephron 18 Nephron 18 Cardiovasc 17 caffeine 12 ROS 11 Anakinra 10 IL-1ra 10 Dial 9 lysine 9 Rasburicase 8 Fructose 8 CSF 7 Indomethacin 7 Monit 4 Leaf 4 niacin 4 vitamin E 4 Rilonacept 4 G-CSF 3 lactose 3 ENT 3 TMX 3 ABC 3 Bifidobacterium 3 IL-2 3 Myricetin 2 citric acid 2 Bumetanide 2 Tenoxicam 2 ampicillin 2 Y-700 2 Etodolac 2 Albumin 2 Tocilizumab 2 Fenoprofen 2 Adenosine triphosphate 2 more...

Enzyme xanthine oxidase 361 uricase 132 caspase-1 65 hypoxanthine-guanine phosphoribosyltransferase 56 xanthine dehydrogenase 35 PRPP synthetase 28 renin 20 peroxidase 17 catalase 14 creatine kinase 13 mitogen-activated protein kinase 13 adenine phosphoribosyltransferase 12 ERK 12 aspartate aminotransferase 12 alanine aminotransferase 12 ACE 11 alkaline phosphatase 11 superoxide dismutase 11 ACS 9 purine nucleoside phosphorylase 9 aldehyde dehydrogenase 9 ATPase 9 aldehyde dehydrogenase 7 glucose-6-phosphatase 7 P-glycoprotein 7 guanase 7 elastase 7 NADPH oxidase 7 calcineurin 7 CYP3A4 7 lactate dehydrogenase 7 focal adhesion kinase 7 NADPH oxidase 7 collagenase 6 proteasome 6 glutathione peroxidase 5 glutathione reductase 5 beta-glucuronidase 5 DNase 5 neutrophil elastase 5 more...

Compound Clin 638 Dec 359 calcium 265 Uric acid 206 creatinine 187 HPP 155 Colchicine 140 sodium 112 glucose 111 potassium 95 oxygen 88 water 87 DNA 69 phosphate 68 TNF 56 ethanol 55 His 55 ATP 50 urea 45 nitrogen 36 hydrogen 35 salt 32 acetate 31 Probenecid 27 pyrimidine 26 pyrimidine 26 PEG 26 nitric oxide 25 Benzbromarone 24 oxalate 24 iron 24 EDTA 21 EDTA 21 methanol 21 Cardiol 19 ammonium 19 molybdenum 18 THP 17 Purine 17 THP 17 more...

---