Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0018099 (gout)
 5,192 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
xanthine oxidase 380
Sep 326
ankylosing spondylitis 106
cytokine 98
insulin 89
NLRP3 88
Mol 81
ABCG2 75
IL-1 74
hypoxanthine-guanine phosphoribosyltransferase 72
chronic renal failure 70
TNF 56
MRI 55
ATP 50
RST 47
SLC2A9 45
C-reactive protein 44
uromodulin 43
IL-6 41
IL-8 38
more...
Disease
gout 5192
hyperuricemia 1159
arthritis 1107
hypertension 555
rheumatoid arthritis 529
diabetes 455
tophi 420
osteoarthritis 336
obesity 272
renal disease 268
arthropathy 188
metabolic syndrome 172
cardiovascular disease 163
cancer 160
pseudogout 150
systemic lupus erythematosus 145
renal failure 128
type 2 diabetes 122
ankylosing spondylitis 113
rheumatism 110
more...
Symptom
pain 371
arthralgia 54
overweight 47
weakness 44
diarrhea 42
back pain 40
low back pain 28
erythema 27
headache 26
angina 23
vomiting 20
nausea 18
knee pain 17
abdominal pain 17
sciatica 16
fatigue 15
myalgia 15
neck pain 14
renal colic 13
acute pain 12
more...
Drug
Febuxostat 74
Dermatol 45
Rasburicase 31
ascorbate 20
Nephron 18
Nephron 18
Cardiovasc 17
caffeine 12
ROS 11
Anakinra 10
IL-1ra 10
Dial 9
lysine 9
Rasburicase 8
Fructose 8
CSF 7
Indomethacin 7
vitamin E 4
Leaf 4
Rilonacept 4
more...
Enzyme
xanthine oxidase 361
uricase 132
caspase-1 65
hypoxanthine-guanine phosphoribosyltransferase 56
xanthine dehydrogenase 35
PRPP synthetase 28
renin 20
peroxidase 17
catalase 14
mitogen-activated protein kinase 13
creatine kinase 13
aspartate aminotransferase 12
alanine aminotransferase 12
ERK 12
adenine phosphoribosyltransferase 12
alkaline phosphatase 11
ACE 11
superoxide dismutase 11
purine nucleoside phosphorylase 9
ATPase 9
more...
Compound
Clin 638
Dec 359
calcium 265
Uric acid 206
creatinine 187
HPP 155
Colchicine 140
sodium 112
glucose 111
potassium 95
oxygen 88
water 87
DNA 69
phosphate 68
TNF 56
ethanol 55
His 55
ATP 50
urea 45
nitrogen 36
more...