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Query: UMLS:C0018099 (gout)
 5,192 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Gout is a condition characterized by the deposition of monosodium urate crystals in the joints or soft tissue. A gouty tophus occasionally mimics an infectious or neoplastic process. However, the conventional enucleating procedure might cause complications. In severe cases, skin necrosis and tendon or joint exposure can occur after debridements. In this series, the soft-tissue shaver is used for deformity management of the chronic tophaceous patients and the results are encouraging. From November 2000 to August 2002, 17 patients with chronic tophaceous gout were treated by the shaver technique. Suction and irrigation were performed simultaneously while the shaver was operating, and chalky deposits of sodium urate could be removed efficiently. Skin necrosis was minimized by means of proper incision planning. Also, bedside debridements and wound wet dressing were helpful for improving the outcomes. The families and patients were satisfied with the results. In conclusion, severe chronic tophaceous gout can be a surgical challenge. The soft-tissue shaving technique can be useful for cosmetic debulking of large tophi in patients with advanced chronic tophaceous gouty arthritis.
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PMID:The soft-tissue shaving procedure for deformity management of chronic tophaceous gout. 1452 64

The development of multiple large tophi in patients with gout is rare. We report magnetic resonance (MR) and histological features of large subcutaneous tophi in a 32-year-old male patient with no known arthritis. His subcutaneous lesions were confused with a neoplastic process, evaluated by MR imaging, and surgically excised after biopsy. The honeycomb-like appearance on the gadolinium-enhanced images may reflect the characteristic multilobular structure of the tophi composed of avascular urate deposits and surrounding vascularized granulation tissue.
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PMID:Characteristic appearance of large subcutaneous gouty tophi in magnetic resonance imaging. 1702 80

The hallux metatarsophalangeal joint (MTPJ) is a common location affected by gouty inflammatory arthritis. Generally, this condition is successfully treated with medication and regular surveillance. Occasionally, gout can lead to advanced arthritic changes and chronic discomfort of the hallux MTPJ, necessitating surgical intervention to help alleviate symptoms. Rarely is the condition isolated to the sesamoid bone, which may lead to a diagnostic dilemma in patients without a history of gout. We report the case of a patient in whom isolated sesamoid changes associated with gout mimicked an aggressive neoplastic process.
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PMID:Gout Causing Isolated Sesamoid Destruction Mimicking a Neoplastic Process. 2644 19