Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0018099 (gout)
 5,192 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The present authors analyzed the pathological alterations of 1966 tendons examined in the National Institute of Traumatology, Budapest, during the past 18 years. The majority of cases proved to be tendinopathies (hypoxic-degenerative tendinopathy or calcific tendinitis, tendolipomatosis and mucoid degeneration) leading to tendon rupture. The incidence of tendon tumors, foreign bodies, infectious tendon diseases, and other pathological conditions was clearly lower. The methods of tissue preparation and of examination of tendon specimens were also evaluated. Light microscopy was sufficient for the diagnosis of pyogenic tendinitis, tumors, xanthoma, gout, and gangrene. In degenerative tendinopathies and alterations due to hereditary disease, electron microscopy was necessary. Polarization microscopy had a key role in examination of collagen structure and architecture, and identification of foreign bodies in the tendons. Enzyme histochemical and immunohistochemical examination were reliable but not absolutely necessary in the diagnosis of tendon pathology.
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PMID:Pathological alterations in human tendons. 228 99

The records of 28 patients who underwent 37 ray resections at Hines Veterans' Administration Hospital and Loyola University Medical Center were reviewed. Indications included localized gangrene, osteomyelitis, or both. Underlying medical diagnoses included diabetes, chronic ethanol abuse, arteriosclerosis obliterans, and gout. The overall success rate was only 34%. These results suggest that the usefulness of ray resections as a definitive procedure in such cases may be limited.
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PMID:Ray resections in the insensitive or dysvascular foot: a critical review. 398 24