Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0017638 (
glioma
)
30,880
document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Mol
2217
Sep
2039
p53
1175
MRI
1031
glial fibrillary acidic protein
678
caspase-3
540
epidermal growth factor receptor
503
AKT
499
cytokine
457
IDH1
450
vascular endothelial growth factor
435
PI3K
425
EGFR
403
Bcl-2
394
methylguanine-DNA methyltransferase
393
ATP
385
mTOR
350
CD133
327
GBM
315
IDH
311
AMP
304
tumor necrosis factor
302
catenin
296
PTEN
290
ERK
279
MAPK
275
VEGF
264
NMR
264
p21
261
histone
250
matrix metalloproteinase
249
tyrosine kinase
248
collagen
243
isocitrate dehydrogenase
242
Ki-67
241
vimentin
236
ERK1
233
endoplasmic reticulum
231
fibronectin
226
isocitrate dehydrogenase 1
224
STAT3
223
thymidine kinase
220
interferon
219
epidermal growth factor
213
MMP-2
212
adenylate cyclase
209
cyclin D1
192
platelet-derived growth factor
191
CD8
188
p38
184
neurofibromatosis
173
MMP-9
172
UTR
169
EGF
160
bradykinin
158
IFN
157
GTP
154
BRAF
152
JNK
151
ADP
149
PARP
149
glycoprotein
147
caspase-8
146
IL-6
145
lipopolysaccharide
144
cytochrome c
144
nestin
143
CD44
141
PEG
139
receptor tyrosine kinase
138
CD4
138
IDH2
138
Fas
136
CSF
134
GSH
133
survivin
129
MEK
129
caspase-9
127
TNF
126
extracellular signal-regulated kinase
125
more...
Disease
glioma
30880
tumor
13459
cancer
9507
glioblastoma
4872
brain tumor
2978
glioblastoma multiforme
2330
tumor growth
1756
astrocytoma
1391
neuroblastoma
1346
tumorigenesis
1168
tumor progression
912
Glioblastoma
882
meningioma
600
melanoma
551
carcinoma
509
oligodendroglioma
477
anaplastic astrocytoma
463
brain cancer
457
breast cancer
437
medulloblastoma
420
metastases
392
epilepsy
346
herpes simplex
314
ependymoma
307
carcinogenesis
302
leukemia
279
intracranial tumors
263
hepatocellular carcinoma
245
lymphoma
240
adenocarcinoma
229
lung cancer
223
aggressiveness
222
primary tumor
201
pertussis
192
prostate cancer
186
Malignant glioma
182
schwannoma
178
tumor angiogenesis
176
neurofibromatosis type 1
176
Alzheimer's disease
171
hydrocephalus
166
neurofibromatosis
163
CNS tumors
163
encephalitis
160
gliosarcoma
157
sarcoma
150
stroke
149
colorectal cancer
144
GSH
133
solid tumor
125
residual disease
125
tumor vasculature
124
multiple sclerosis
124
osteosarcoma
119
colon cancer
116
tumor initiation
112
suicide
110
depression
109
gastric cancer
103
ovarian cancer
103
retinoblastoma
103
MCF
100
pituitary adenoma
98
craniopharyngioma
96
lung carcinoma
95
squamous cell carcinoma
95
ATRX
95
cytomegalovirus
93
brain metastases
93
thrombocytopenia
91
acute myeloid leukemia
90
renal cell carcinoma
90
primitive neuroectodermal tumor
86
pancreatic cancer
84
pheochromocytoma
83
cholera
83
AS1
81
brain edema
80
ischemia
78
ganglioglioma
77
more...
Symptom
seizures
521
headache
214
pain
85
starvation
72
vomiting
70
weakness
67
fatigue
63
anesthesia
63
nausea
58
ataxia
33
collapse
32
HSA
31
diarrhea
30
dizziness
25
vertigo
23
paresis
22
dysarthria
21
hemiplegia
21
nausea and vomiting
20
sleepiness
20
exhaustion
17
respiratory distress
16
functional recovery
16
insomnia
14
anorexia
14
hypothermia
13
back pain
11
discomfort
11
numbness
11
constipation
11
analgesia
10
Scratch
10
lethargy
10
memory loss
9
tonic-clonic seizure
9
tremor
8
acidity
8
cough
8
cerebellar ataxia
8
spasm
8
thinning
7
pallor
7
tinnitus
7
consciousness disturbance
7
ENT
7
agitation
7
chills
7
twitching
7
blurred vision
6
rhinorrhea
6
splenomegaly
6
myalgia
6
emaciation
5
ophthalmoplegia
5
dysesthesia
5
abdominal pain
5
overweight
5
flushing
5
erythema
5
cachexia
4
Ill
4
dystonia
4
polydipsia
4
neck pain
4
partial seizure
4
paraparesis
4
dyspnea
4
polyuria
4
syncope
4
discomfort
4
asthenia
4
myoclonus
4
chorea
4
hyperoxia
4
skin damage
3
paresthesia
3
low back pain
3
arthralgia
3
tense
3
apathy
3
more...
Drug
CSF
161
lysine
158
ROS
112
IFN-gamma
104
ALA
92
Bevacizumab
69
IL-2
65
Monit
43
MAP
41
Taxol
40
CPT-11
36
Gel
36
IFN-beta
35
caffeine
33
ROC
31
Gliadel
29
ABC
27
ascorbate
27
p75
26
NADH
25
vitamin E
24
DNase I
23
Adriamycin
22
Photofrin
21
Dermatol
21
G418
21
GEO
21
TAT
19
uPA
19
L-tyrosine
19
NVP
18
Gefitinib
18
CTX
18
CAM
18
Fluorescein
18
Ethanol
18
Temodal
17
Glutathione
17
Irinotecan
16
Forskolin
16
ICI
16
Etoposide
15
MRC
15
Imatinib
15
Cilengitide
15
Nephron
15
RFP
15
ADR
14
Indomethacin
14
TTC
14
Erlotinib
13
Gelatin
13
Asn
13
ADM
12
Retinoic acid
12
Magnevist
12
Docetaxel
12
CoCl2
11
CoCl2
11
Ganciclovir
11
Gleevec
11
Dasatinib
10
Fluorescein
10
Paraffin
10
VCR
10
Arsenic trioxide
10
VCR
9
Bortezomib
9
Heme
9
ENT
9
Vitamin E
9
Angiotensin II
8
Nitric Oxide
8
BLM
8
Ouabain
8
Leaf
8
Simvastatin
8
Sorafenib
8
Amiloride
8
ETA
7
more...
Enzyme
ERK
1048
mitogen-activated protein kinase
830
luciferase
582
protein kinase
407
protein kinase C
386
caspase-3
383
focal adhesion kinase
306
isocitrate dehydrogenase
243
isocitrate dehydrogenase
242
adenylate cyclase
221
thymidine kinase
220
MEK
168
PARP
165
ATPase
122
ACS
121
proteasome
111
phospholipase C
111
phosphatidylinositol 3-kinase
109
catalase
104
caspase-8
100
reverse transcriptase
92
P-glycoprotein
91
caspase-9
91
lactate dehydrogenase
84
peroxidase
81
urokinase-type plasminogen activator
80
superoxide dismutase
77
DNA methyltransferase
74
phosphodiesterase
73
beta-galactosidase
69
cdc2
66
AMP-activated protein kinase
65
glutathione S-transferase
65
trypsin
62
cytosine deaminase
62
GSK
59
AMPK
59
MMP
57
phosphoinositide 3-kinase
57
topoisomerase
55
calcineurin
53
RNA polymerase
51
cathepsin B
50
topoisomerase
50
glutamine synthetase
46
phospholipase A2
41
RNase
41
AMPK
39
RNase
39
thrombin
39
DNA ligase
38
DNA ligase
38
matrix metalloproteinase 2
36
collagenase
36
NO synthase
35
glutathione peroxidase
34
alkaline phosphatase
34
MAP
33
lipoxygenase
32
plasmin
31
hexokinase
29
phospholipase D
29
ornithine decarboxylase
29
firefly luciferase
28
monoamine oxidase
27
transcriptase
26
NOS
26
chloramphenicol acetyltransferase
25
hyaluronidase
24
endonuclease
24
guanylate cyclase
24
neuraminidase
23
enolase
23
PDK1
23
APC
23
complex I
22
DNA polymerase
21
IKK
21
CaMKII
20
glutathione reductase
20
more...
Compound
DNA
2655
Dec
2035
Clin
1157
calcium
777
oxygen
768
MTT
628
sodium
524
water
430
glucose
430
ATP
386
tyrosine
381
glutamate
371
cAMP
369
leucine
351
AMP
313
BCNU
307
Temozolomide
301
methionine
283
phosphate
253
PEG
247
acetate
246
iron
246
arginine
229
nitric oxide
216
lysine
201
serine
193
sulfate
190
PEG
180
iodine
174
ACNU
165
bromide
165
boron
164
cysteine
163
GTP
158
hydrogen
156
ADP
155
hydroxyglutarate
150
ADP
150
ADP
149
GSH
142
GSH
142
potassium
140
TNF
126
retinoic acid
126
ACS
126
MEK
124
ACS
121
galactose
114
bis(2-chloroethyl)
113
bis(2-chloroethyl)
110
bis(2-chloroethyl)
110
glutamine
104
alanine
103
ethanol
100
MDA
95
Phe
90
prostaglandin E1
90
zinc
89
threonine
87
DTPA
83
Asp
81
His
80
CCNU
79
urea
77
Gly
76
2-oxoglutarate
72
cGMP
71
SDS
69
nitrogen
69
NAD
68
hyaluronic acid
66
dUTP
66
DDP
65
copper
65
isocitrate
64
5-HT
63
TEM
62
manganese
62
salt
61
GM1
61
more...