Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0017638 (glioma)
30,880 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Mol 2217
Sep 2039
p53 1175
MRI 1031
glial fibrillary acidic protein 678
caspase-3 540
epidermal growth factor receptor 503
AKT 499
cytokine 457
IDH1 450
vascular endothelial growth factor 435
PI3K 425
EGFR 403
Bcl-2 394
methylguanine-DNA methyltransferase 393
ATP 385
mTOR 350
CD133 327
GBM 315
IDH 311
AMP 304
tumor necrosis factor 302
catenin 296
PTEN 290
ERK 279
MAPK 275
VEGF 264
NMR 264
p21 261
histone 250
matrix metalloproteinase 249
tyrosine kinase 248
collagen 243
isocitrate dehydrogenase 242
Ki-67 241
vimentin 236
ERK1 233
endoplasmic reticulum 231
fibronectin 226
isocitrate dehydrogenase 1 224
STAT3 223
thymidine kinase 220
interferon 219
epidermal growth factor 213
MMP-2 212
adenylate cyclase 209
cyclin D1 192
platelet-derived growth factor 191
CD8 188
p38 184
neurofibromatosis 173
MMP-9 172
UTR 169
EGF 160
bradykinin 158
IFN 157
GTP 154
BRAF 152
JNK 151
ADP 149
PARP 149
glycoprotein 147
caspase-8 146
IL-6 145
lipopolysaccharide 144
cytochrome c 144
nestin 143
CD44 141
PEG 139
receptor tyrosine kinase 138
CD4 138
IDH2 138
Fas 136
CSF 134
GSH 133
survivin 129
MEK 129
caspase-9 127
TNF 126
extracellular signal-regulated kinase 125
more...
Disease
glioma 30880
tumor 13459
cancer 9507
glioblastoma 4872
brain tumor 2978
glioblastoma multiforme 2330
tumor growth 1756
astrocytoma 1391
neuroblastoma 1346
tumorigenesis 1168
tumor progression 912
Glioblastoma 882
meningioma 600
melanoma 551
carcinoma 509
oligodendroglioma 477
anaplastic astrocytoma 463
brain cancer 457
breast cancer 437
medulloblastoma 420
metastases 392
epilepsy 346
herpes simplex 314
ependymoma 307
carcinogenesis 302
leukemia 279
intracranial tumors 263
hepatocellular carcinoma 245
lymphoma 240
adenocarcinoma 229
lung cancer 223
aggressiveness 222
primary tumor 201
pertussis 192
prostate cancer 186
Malignant glioma 182
schwannoma 178
tumor angiogenesis 176
neurofibromatosis type 1 176
Alzheimer's disease 171
hydrocephalus 166
neurofibromatosis 163
CNS tumors 163
encephalitis 160
gliosarcoma 157
sarcoma 150
stroke 149
colorectal cancer 144
GSH 133
solid tumor 125
residual disease 125
tumor vasculature 124
multiple sclerosis 124
osteosarcoma 119
colon cancer 116
tumor initiation 112
suicide 110
depression 109
gastric cancer 103
ovarian cancer 103
retinoblastoma 103
MCF 100
pituitary adenoma 98
craniopharyngioma 96
lung carcinoma 95
squamous cell carcinoma 95
ATRX 95
cytomegalovirus 93
brain metastases 93
thrombocytopenia 91
acute myeloid leukemia 90
renal cell carcinoma 90
primitive neuroectodermal tumor 86
pancreatic cancer 84
pheochromocytoma 83
cholera 83
AS1 81
brain edema 80
ischemia 78
ganglioglioma 77
more...
Symptom
seizures 521
headache 214
pain 85
starvation 72
vomiting 70
weakness 67
fatigue 63
anesthesia 63
nausea 58
ataxia 33
collapse 32
HSA 31
diarrhea 30
dizziness 25
vertigo 23
paresis 22
dysarthria 21
hemiplegia 21
nausea and vomiting 20
sleepiness 20
exhaustion 17
respiratory distress 16
functional recovery 16
insomnia 14
anorexia 14
hypothermia 13
back pain 11
discomfort 11
numbness 11
constipation 11
analgesia 10
Scratch 10
lethargy 10
memory loss 9
tonic-clonic seizure 9
tremor 8
acidity 8
cough 8
cerebellar ataxia 8
spasm 8
thinning 7
pallor 7
tinnitus 7
consciousness disturbance 7
ENT 7
agitation 7
chills 7
twitching 7
blurred vision 6
rhinorrhea 6
splenomegaly 6
myalgia 6
emaciation 5
ophthalmoplegia 5
dysesthesia 5
abdominal pain 5
overweight 5
flushing 5
erythema 5
cachexia 4
Ill 4
dystonia 4
polydipsia 4
neck pain 4
partial seizure 4
paraparesis 4
dyspnea 4
polyuria 4
syncope 4
discomfort 4
asthenia 4
myoclonus 4
chorea 4
hyperoxia 4
skin damage 3
paresthesia 3
low back pain 3
arthralgia 3
tense 3
apathy 3
more...
Drug
CSF 161
lysine 158
ROS 112
IFN-gamma 104
ALA 92
Bevacizumab 69
IL-2 65
Monit 43
MAP 41
Taxol 40
CPT-11 36
Gel 36
IFN-beta 35
caffeine 33
ROC 31
Gliadel 29
ABC 27
ascorbate 27
p75 26
NADH 25
vitamin E 24
DNase I 23
Adriamycin 22
Photofrin 21
Dermatol 21
G418 21
GEO 21
TAT 19
uPA 19
L-tyrosine 19
NVP 18
Gefitinib 18
CTX 18
CAM 18
Fluorescein 18
Ethanol 18
Temodal 17
Glutathione 17
Irinotecan 16
Forskolin 16
ICI 16
Etoposide 15
MRC 15
Imatinib 15
Cilengitide 15
Nephron 15
RFP 15
ADR 14
Indomethacin 14
TTC 14
Erlotinib 13
Gelatin 13
Asn 13
ADM 12
Retinoic acid 12
Magnevist 12
Docetaxel 12
CoCl2 11
CoCl2 11
Ganciclovir 11
Gleevec 11
Dasatinib 10
Fluorescein 10
Paraffin 10
VCR 10
Arsenic trioxide 10
VCR 9
Bortezomib 9
Heme 9
ENT 9
Vitamin E 9
Angiotensin II 8
Nitric Oxide 8
BLM 8
Ouabain 8
Leaf 8
Simvastatin 8
Sorafenib 8
Amiloride 8
ETA 7
more...
Enzyme
ERK 1048
mitogen-activated protein kinase 830
luciferase 582
protein kinase 407
protein kinase C 386
caspase-3 383
focal adhesion kinase 306
isocitrate dehydrogenase 243
isocitrate dehydrogenase 242
adenylate cyclase 221
thymidine kinase 220
MEK 168
PARP 165
ATPase 122
ACS 121
proteasome 111
phospholipase C 111
phosphatidylinositol 3-kinase 109
catalase 104
caspase-8 100
reverse transcriptase 92
P-glycoprotein 91
caspase-9 91
lactate dehydrogenase 84
peroxidase 81
urokinase-type plasminogen activator 80
superoxide dismutase 77
DNA methyltransferase 74
phosphodiesterase 73
beta-galactosidase 69
cdc2 66
AMP-activated protein kinase 65
glutathione S-transferase 65
trypsin 62
cytosine deaminase 62
GSK 59
AMPK 59
MMP 57
phosphoinositide 3-kinase 57
topoisomerase 55
calcineurin 53
RNA polymerase 51
cathepsin B 50
topoisomerase 50
glutamine synthetase 46
phospholipase A2 41
RNase 41
AMPK 39
RNase 39
thrombin 39
DNA ligase 38
DNA ligase 38
matrix metalloproteinase 2 36
collagenase 36
NO synthase 35
glutathione peroxidase 34
alkaline phosphatase 34
MAP 33
lipoxygenase 32
plasmin 31
hexokinase 29
phospholipase D 29
ornithine decarboxylase 29
firefly luciferase 28
monoamine oxidase 27
transcriptase 26
NOS 26
chloramphenicol acetyltransferase 25
hyaluronidase 24
endonuclease 24
guanylate cyclase 24
neuraminidase 23
enolase 23
PDK1 23
APC 23
complex I 22
DNA polymerase 21
IKK 21
CaMKII 20
glutathione reductase 20
more...
Compound
DNA 2655
Dec 2035
Clin 1157
calcium 777
oxygen 768
MTT 628
sodium 524
water 430
glucose 430
ATP 386
tyrosine 381
glutamate 371
cAMP 369
leucine 351
AMP 313
BCNU 307
Temozolomide 301
methionine 283
phosphate 253
PEG 247
acetate 246
iron 246
arginine 229
nitric oxide 216
lysine 201
serine 193
sulfate 190
PEG 180
iodine 174
ACNU 165
bromide 165
boron 164
cysteine 163
GTP 158
hydrogen 156
ADP 155
hydroxyglutarate 150
ADP 150
ADP 149
GSH 142
GSH 142
potassium 140
TNF 126
retinoic acid 126
ACS 126
MEK 124
ACS 121
galactose 114
bis(2-chloroethyl) 113
bis(2-chloroethyl) 110
bis(2-chloroethyl) 110
glutamine 104
alanine 103
ethanol 100
MDA 95
Phe 90
prostaglandin E1 90
zinc 89
threonine 87
DTPA 83
Asp 81
His 80
CCNU 79
urea 77
Gly 76
2-oxoglutarate 72
cGMP 71
SDS 69
nitrogen 69
NAD 68
hyaluronic acid 66
dUTP 66
DDP 65
copper 65
isocitrate 64
5-HT 63
TEM 62
manganese 62
salt 61
GM1 61
more...