Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0017638 (glioma)
 30,880 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Mol 2217
Sep 2039
p53 1175
MRI 1031
glial fibrillary acidic protein 678
caspase-3 540
epidermal growth factor receptor 503
AKT 499
cytokine 457
IDH1 450
vascular endothelial growth factor 435
PI3K 425
EGFR 403
Bcl-2 394
methylguanine-DNA methyltransferase 393
ATP 385
mTOR 350
CD133 327
GBM 315
IDH 311
AMP 304
tumor necrosis factor 302
catenin 296
PTEN 290
ERK 279
MAPK 275
NMR 264
VEGF 264
p21 261
histone 250
matrix metalloproteinase 249
tyrosine kinase 248
collagen 243
isocitrate dehydrogenase 242
Ki-67 241
vimentin 236
ERK1 233
endoplasmic reticulum 231
fibronectin 226
isocitrate dehydrogenase 1 224
STAT3 223
thymidine kinase 220
interferon 219
epidermal growth factor 213
MMP-2 212
adenylate cyclase 209
cyclin D1 192
platelet-derived growth factor 191
CD8 188
p38 184
neurofibromatosis 173
MMP-9 172
UTR 169
EGF 160
bradykinin 158
IFN 157
GTP 154
BRAF 152
JNK 151
ADP 149
PARP 149
glycoprotein 147
caspase-8 146
IL-6 145
cytochrome c 144
lipopolysaccharide 144
nestin 143
CD44 141
PEG 139
CD4 138
receptor tyrosine kinase 138
IDH2 138
Fas 136
CSF 134
GSH 133
survivin 129
MEK 129
caspase-9 127
TNF 126
annexin V 125
extracellular signal-regulated kinase 125
nerve growth factor 124
p16 124
phosphatase 120
ACS 120
adenylyl cyclase 118
PDGF 115
inducible nitric oxide synthase 115
chemokine 113
polypeptide 112
ROS 112
osteosarcoma 112
regulated in glioma 112
fused 111
ATPase 110
IFN-gamma 110
phosphatidylinositol 3-kinase 109
proteasome 108
insulin 108
E-cadherin 108
CXCR4 107
interleukin-2 106
She 104
Nestin 103
proliferating cell nuclear antigen 102
methyltransferase 101
TERT 100
neurofibromatosis type 1 100
histone deacetylase 100
histone H3 100
CDKN2A 99
LC3 98
interferon-gamma 98
p27 98
IL-8 96
ubiquitin 96
c-Jun 96
CCK 96
ATRX 95
PKC 94
opioid receptor 92
TRAIL 92
MIB 91
MMP9 90
Rho 90
transferrin 89
P-glycoprotein 88
VEGFR2 87
focal adhesion kinase 87
EGF receptor 86
p65 85
N-cadherin 85
c-Myc 85
kit 85
ALA 84
nitric oxide synthase 83
beta 1 83
scratch 82
SOX2 81
rhabdomyosarcoma 81
lactate dehydrogenase 81
AS1 81
AP-1 79
CCNU 78
signal transducer and activator of transcription 3 78
MMP2 78
calmodulin 78
TGF-beta 77
metalloproteinase 77
cyclin 76
TNF-alpha 76
hepatocyte growth factor 75
proteoglycan 75
phosphatase and tensin homolog 75
membrane-bound 75
catalase 74
CDK4 74
CD31 74
FAK 73
lymphokine 73
more...
Disease
glioma 30880
tumor 13459
cancer 9507
glioblastoma 4872
brain tumor 2978
glioblastoma multiforme 2330
tumor growth 1756
astrocytoma 1391
neuroblastoma 1346
tumorigenesis 1168
tumor progression 912
Glioblastoma 882
meningioma 600
melanoma 551
carcinoma 509
oligodendroglioma 477
anaplastic astrocytoma 463
brain cancer 457
breast cancer 437
medulloblastoma 420
metastases 392
epilepsy 346
herpes simplex 314
ependymoma 307
carcinogenesis 302
leukemia 279
intracranial tumors 263
hepatocellular carcinoma 245
lymphoma 240
adenocarcinoma 229
lung cancer 223
aggressiveness 222
primary tumor 201
pertussis 192
prostate cancer 186
Malignant glioma 182
schwannoma 178
neurofibromatosis type 1 176
tumor angiogenesis 176
Alzheimer's disease 171
hydrocephalus 166
CNS tumors 163
neurofibromatosis 163
encephalitis 160
gliosarcoma 157
sarcoma 150
stroke 149
colorectal cancer 144
GSH 133
residual disease 125
solid tumor 125
multiple sclerosis 124
tumor vasculature 124
osteosarcoma 119
colon cancer 116
tumor initiation 112
suicide 110
depression 109
ovarian cancer 103
retinoblastoma 103
gastric cancer 103
MCF 100
pituitary adenoma 98
craniopharyngioma 96
ATRX 95
squamous cell carcinoma 95
lung carcinoma 95
cytomegalovirus 93
brain metastases 93
thrombocytopenia 91
renal cell carcinoma 90
acute myeloid leukemia 90
primitive neuroectodermal tumor 86
pancreatic cancer 84
pheochromocytoma 83
cholera 83
AS1 81
brain edema 80
ischemia 78
ganglioglioma 77
hemiparesis 76
multiple myeloma 75
hypertension 75
primitive neuroectodermal tumor 75
bladder cancer 73
ATM 72
non-small cell lung cancer 72
mimicry 71
Parkinson's disease 70
neutropenia 69
aggression 69
HIV 68
myelosuppression 68
B-cell lymphoma 67
rhabdomyosarcoma 67
fibrosarcoma 66
SCID 65
Blocking 63
MRS 63
SDS 62
acoustic neuroma 59
diabetes 59
tuberous sclerosis 59
Neuroblastoma 58
Neuroblastoma 58
hemangioma 56
DDP 55
neoplastic transformation 55
temporal lobe epilepsy 55
cognitive impairment 55
virus infection 54
teratoma 53
pediatric brain tumor 53
infectious diseases 52
MRT 51
cervical cancer 51
Hodgkin's disease 50
acute lymphoblastic leukemia 49
EMT 48
Evans 48
cold 46
neurological disease 46
fits 46
immunodeficiency 45
dysplasia 44
primary central nervous system lymphoma 44
Tumour necrosis 43
germinoma 43
schizophrenia 42
epithelial ovarian cancer 42
dementia 41
plaque 40
meningitis 39
liver cancer 39
mixed gliomas 39
PNET 38
WT1 38
TEM 38
encephalopathy 37
TEM 37
pituitary tumor 37
aphasia 37
liver cancer 36
measles 36
herpes 35
confusion 35
hemangioblastoma 34
AIDS 34
chondrosarcoma 34
meninges 34
HGF 34
Hippel 34
MTS 33
arteriovenous malformation 33
asthma 33
neurofibroma 33
Infection 32
adenoma 32
Pilocytic astrocytoma 32
ARF 32
more...
Symptom
seizures 521
headache 214
pain 85
starvation 72
vomiting 70
weakness 67
anesthesia 63
fatigue 63
nausea 58
ataxia 33
collapse 32
HSA 31
diarrhea 30
dizziness 25
vertigo 23
paresis 22
dysarthria 21
hemiplegia 21
sleepiness 20
nausea and vomiting 20
exhaustion 17
functional recovery 16
respiratory distress 16
insomnia 14
anorexia 14
hypothermia 13
numbness 11
discomfort 11
constipation 11
back pain 11
analgesia 10
lethargy 10
Scratch 10
memory loss 9
tonic-clonic seizure 9
tremor 8
cerebellar ataxia 8
cough 8
acidity 8
spasm 8
ENT 7
twitching 7
agitation 7
thinning 7
consciousness disturbance 7
pallor 7
tinnitus 7
chills 7
blurred vision 6
myalgia 6
rhinorrhea 6
splenomegaly 6
ophthalmoplegia 5
dysesthesia 5
emaciation 5
overweight 5
abdominal pain 5
erythema 5
flushing 5
partial seizure 4
chorea 4
syncope 4
polyuria 4
dyspnea 4
Ill 4
cachexia 4
discomfort 4
asthenia 4
polydipsia 4
dystonia 4
neck pain 4
paraparesis 4
myoclonus 4
hyperoxia 4
low back pain 3
ataxic gait 3
paresthesia 3
apathy 3
tense 3
skin damage 3
arthralgia 3
cancer pain 2
hypercapnia 2
personality change 2
bone pain 2
leg pain 2
muscle cramps 2
loss of taste 2
neurological disability 2
spasticity 2
cyanosis 2
gumma 2
bitter taste 2
torticollis 2
hypersomnia 2
dry skin 2
shoulder pain 2
intention tremor 2
hypotonia 2
tingling 2
stigma 1
masculinization 1
excessive urination 1
shortness of breath 1
hepatomegaly 1
wheezing 1
hunger 1
snoring 1
hypocapnia 1
forgetfulness 1
decreased appetite 1
Inspiratory stridor 1
Chills and fever 1
ACHE 1
sinus congestion 1
skin irritation 1
epigastric pain 1
orthopnea 1
renal colic 1
hemihypesthesia 1
chest pain 1
hypalgesia 1
stridor 1
photophobia 1
regurgitation 1
angina 1
Depressive symptoms 1
nasal discharge 1
Psychiatric symptoms 1
anosmia 1
testicular pain 1
loss of equilibrium 1
dental pain 1
Physical findings 1
bradykinesia 1
Divergence paralysis 1
Postoperative nausea and vomiting 1
enuresis 1
right upper quadrant pain 1
catatonia 1
arm pain 1
eds 1
facial droop 1
rundown 1
facial pain 1
fasciculation 1
General symptoms 1
abnormal gait 1
metamorphopsia 1
fever of unknown origin 1
dry eye 1
gustatory hallucination 1
Mills 1
Halo 1
POA 1
athetosis 1
incoordination 1
clumsiness 1
halitosis 1
Drug
CSF 161
lysine 158
ROS 112
IFN-gamma 104
ALA 92
Bevacizumab 69
IL-2 65
Monit 43
MAP 41
Taxol 40
Gel 36
CPT-11 36
IFN-beta 35
caffeine 33
ROC 31
Gliadel 29
ascorbate 27
ABC 27
p75 26
NADH 25
vitamin E 24
DNase I 23
Adriamycin 22
Dermatol 21
Photofrin 21
GEO 21
G418 21
L-tyrosine 19
uPA 19
TAT 19
CAM 18
CTX 18
Fluorescein 18
NVP 18
Ethanol 18
Gefitinib 18
Temodal 17
Glutathione 17
Irinotecan 16
Forskolin 16
ICI 16
Cilengitide 15
Imatinib 15
Nephron 15
MRC 15
RFP 15
Etoposide 15
ADR 14
Indomethacin 14
TTC 14
Asn 13
Erlotinib 13
Gelatin 13
Retinoic acid 12
Docetaxel 12
Magnevist 12
ADM 12
CoCl2 11
CoCl2 11
Ganciclovir 11
Gleevec 11
Paraffin 10
Arsenic trioxide 10
Fluorescein 10
Dasatinib 10
VCR 10
Bortezomib 9
VCR 9
Heme 9
Vitamin E 9
ENT 9
Nitric Oxide 8
Amiloride 8
Simvastatin 8
Leaf 8
Sorafenib 8
Ouabain 8
Angiotensin II 8
BLM 8
Amiloride 7
Monensin 7
Histamine 7
ETA 7
CCL 7
Mutagen 7
CTC 7
CTC 7
Emodin 7
Fructose 6
CaCl2 6
Vorinostat 6
Trapidil 6
3-Methyladenine 6
CTX 6
CaCl2 6
EE2 6
Lovastatin 6
citric acid 6
NOV 6
CaCl2 6
MDM 6
CTX 6
Cetuximab 6
EPI 6
Emodin 6
Fotemustine 6
pyridoxal phosphate 5
Frontal 5
FAD 5
Fluorescein sodium 5
Verteporfin 5
Optison 5
Cardiovasc 5
CDX 5
Vandetanib 5
CDP 5
Spectrum 5
DEX 5
CDX 5
Phosphatidylserine 5
Trifluoperazine 5
Troglitazone 5
G-CSF 5
Albumin 4
Alanine 4
Orphan 4
Epigallocatechin 4
ACT 4
Biopolymers 4
Rolipram 4
NAG 4
Parkin 4
AMC 4
Marimastat 4
Parkin 4
ETS 4
Taxotere 4
Reserpine 4
EPA 4
Fraction 4
Doxycycline 4
Phenytoin 4
Diamminedichloroplatinum 4
Sodium valproate 4
Aloe 4
ZnCl2 3
CSI 3
beta-Galactosidase 3
MDS 3
Sodium nitroprusside 3
Propentofylline 3
AZT 3
PMEA 3
Tetrofosmin 3
Thioridazine 3
PDL 3
Oxaliplatin 3
Propofol 3
Bumetanide 3
Zoledronic acid 3
more...
Enzyme
ERK 1048
mitogen-activated protein kinase 830
luciferase 582
protein kinase 407
protein kinase C 386
caspase-3 383
focal adhesion kinase 306
isocitrate dehydrogenase 243
isocitrate dehydrogenase 242
adenylate cyclase 221
thymidine kinase 220
MEK 168
PARP 165
ATPase 122
ACS 121
proteasome 111
phospholipase C 111
phosphatidylinositol 3-kinase 109
catalase 104
caspase-8 100
reverse transcriptase 92
caspase-9 91
P-glycoprotein 91
lactate dehydrogenase 84
peroxidase 81
urokinase-type plasminogen activator 80
superoxide dismutase 77
DNA methyltransferase 74
phosphodiesterase 73
beta-galactosidase 69
cdc2 66
glutathione S-transferase 65
AMP-activated protein kinase 65
trypsin 62
cytosine deaminase 62
AMPK 59
GSK 59
phosphoinositide 3-kinase 57
MMP 57
topoisomerase 55
calcineurin 53
RNA polymerase 51
topoisomerase 50
cathepsin B 50
glutamine synthetase 46
phospholipase A2 41
RNase 41
thrombin 39
RNase 39
AMPK 39
DNA ligase 38
DNA ligase 38
matrix metalloproteinase 2 36
collagenase 36
NO synthase 35
glutathione peroxidase 34
alkaline phosphatase 34
MAP 33
lipoxygenase 32
plasmin 31
hexokinase 29
ornithine decarboxylase 29
phospholipase D 29
firefly luciferase 28
monoamine oxidase 27
NOS 26
transcriptase 26
chloramphenicol acetyltransferase 25
endonuclease 24
hyaluronidase 24
guanylate cyclase 24
APC 23
enolase 23
neuraminidase 23
PDK1 23
complex I 22
IKK 21
DNA polymerase 21
glutathione reductase 20
CaMKII 20
IMP dehydrogenase 20
glyceraldehyde-3-phosphate dehydrogenase 20
TAT 19
acetylcholinesterase 19
tyrosine hydroxylase 18
CNPase 18
dihydrofolate reductase 17
caspase-7 17
choline acetyltransferase 17
CD10 17
caspase-7 17
hyaluronidase 17
glycerol-3-phosphate dehydrogenase 16
pyruvate kinase 16
gamma-glutamyl transpeptidase 16
glycerol-3-phosphate dehydrogenase 16
matrix metalloproteinase 9 16
tissue plasminogen activator 16
MDR 15
demethylase 15
arginase 14
caspase-1 14
MMP-3 14
aldehyde dehydrogenase 14
aspartate aminotransferase 13
GRK2 13
adenosine deaminase 13
succinate dehydrogenase 13
pyruvate dehydrogenase 13
carboxylesterase 13
adenosine deaminase 13
ribonucleotide reductase 13
TdT 13
renin 13
aldehyde dehydrogenase 13
chymotrypsin 12
5'-nucleotidase 12
glyceraldehyde-3-phosphate dehydrogenase 12
CPT 12
transglutaminase 12
ribonucleotide reductase 12
thymidylate synthase 12
PDE 12
aldehyde dehydrogenase 11
furin 11
GRK5 11
NADPH oxidase 11
protein phosphatase 2A 11
NADPH oxidase 11
cathepsin D 11
heme oxygenase 11
polo-like kinase 1 11
acid phosphatase 11
sialyltransferase 11
sialyltransferase 11
DCF 11
sialyltransferase 11
deaminase 11
aldehyde dehydrogenase 11
aldehyde dehydrogenase 11
cytochrome oxidase 10
thioredoxin reductase 10
granzyme B 10
alanine aminotransferase 10
farnesyltransferase 10
CPT 10
farnesyltransferase 10
lysozyme 10
creatine kinase 10
ceruloplasmin 10
PKG 10
CPT 10
neutral sphingomyelinase 10
ricin 9
pyruvate dehydrogenase 9
prolyl hydroxylase 9
pyruvate dehydrogenase 9
purine nucleoside phosphorylase 9
glutaminase 9
chitinase 9
more...
Compound
DNA 2655
Dec 2035
Clin 1157
calcium 777
oxygen 768
MTT 628
sodium 524
water 430
glucose 430
ATP 386
tyrosine 381
glutamate 371
cAMP 369
leucine 351
AMP 313
BCNU 307
Temozolomide 301
methionine 283
phosphate 253
PEG 247
iron 246
acetate 246
arginine 229
nitric oxide 216
lysine 201
serine 193
sulfate 190
PEG 180
iodine 174
ACNU 165
bromide 165
boron 164
cysteine 163
GTP 158
hydrogen 156
ADP 155
ADP 150
hydroxyglutarate 150
ADP 149
GSH 142
GSH 142
potassium 140
TNF 126
ACS 126
retinoic acid 126
MEK 124
ACS 121
galactose 114
bis(2-chloroethyl) 113
bis(2-chloroethyl) 110
bis(2-chloroethyl) 110
glutamine 104
alanine 103
ethanol 100
MDA 95
Phe 90
prostaglandin E1 90
zinc 89
threonine 87
DTPA 83
Asp 81
His 80
CCNU 79
urea 77
Gly 76
2-oxoglutarate 72
cGMP 71
nitrogen 69
SDS 69
NAD 68
dUTP 66
hyaluronic acid 66
DDP 65
copper 65
isocitrate 64
5-HT 63
TEM 62
manganese 62
GM1 61
salt 61
Adriamycin 60
NH2 59
H2O2 59
tryptophan 58
NADPH 56
NADPH 56
ADR 55
Leucine 54
N-acetylcysteine 51
Pac 51
silver 51
NAD 50
tryptophan 48
acridine 48
cobalt 48
Glutamate 47
tryptophan 47
tryptophan 47
N-acetylaspartate 47
pyrimidine 46
uridine 45
pyrimidine 45
ASA 44
COS 43
Mg2+ 43
Dexamethasone 42
ammonium 42
cadmium 42
Lactate 42
nicotinamide 42
noradrenaline 41
Curcumin 40
glycerol 40
CO2 39
PMA 39
Cereb 38
UTP 38
glutamic acid 37
GM3 37
GABA 37
GABA 37
fluorine 37
VP-16 36
CPT-11 36
phosphocreatine 34
GD3 34
ADP-ribose 34
methanol 33
caffeine 33
MAP 33
PLA 33
CAT 33
NADP 32
GM2 32
CBDCA 32
Resveratrol 32
CAT 32
MTS 32
CAT 32
CBDCA 32
Vimentin 31
acetic acid 31
Bradykinin 30
Ile 30
Insulin 30
BSH 30
PMA 30
TOF 30
DMSO 30
Histone 29
proline 29
pentose 28
pentose 28
gamma-aminobutyric acid 28
NMDA 28
pentose 28
Valproic acid 28
pentose 28
selenium 28
Neuronal 27
more...