Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0017638 (
glioma
)
30,880
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Cyclin Y
(
CCNY
) is a novel cyclin and almost nothing is known about its expression level and role in human cancers. In the present study, we found that lentivirus-mediated RNA interference (RNAi) of
CCNY
significantly downregulated its expression level. More importantly, knockdown of
CCNY
inhibited cell proliferation, colony formation, and cell cycle progression in
glioma
cells. These data suggest that
CCNY
might play an important role in
glioma
tumorigenisis.
...
PMID:Lentivirus-mediated knockdown of cyclin Y (CCNY) inhibits glioma cell proliferation. 2044 Oct 50
