Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0017638 (
glioma
)
30,880
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
We studied effects of NO-donor iron nitrosyl complex with
N
-ethylthiourea ligand (
ETM
) on normal or tumor-derived cell lines.
ETM
was mildly toxic to most cell lines studied except the human
glioma
cell line A172 that proved to be highly sensitive to the complex and underwent cell death after
ETM
exposure. The high susceptibility of A172 cells to
ETM
was attributed to its NO-donor properties since no toxicity was detected for the
N
-ethylthiourea ligand.
...
PMID:NO-Donor Iron Nitrosyl Complex with N-Ethylthiourea Ligand Exhibits Selective Toxicity to Glioma A172 Cells. 2885 75
