Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0017638 (glioma)
 30,880 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Chordoid glioma is a rare low-grade tumor that originates almost exclusively in the anterior part of the third ventricle. The diagnosis and treatment of the tumor remain controversial. In this article, the authors present a novel case of chordoid glioma of the third ventricle. The patient was treated with less invasive microsurgery followed by low-dose gamma knife radiosurgery. Magnetic resonance imaging revealed a decrease in tumor size and necrosis in the central region of the tumor, without significant complications at follow-up 14 months later. Based on these findings, the authors suggest that less invasive microsurgical resection followed by low-dose gamma knife radiosurgery is safe and effective for the treatment of chordoid glioma of the third ventricle.
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PMID:Chordoid Glioma: A Neoplasm Found in the Anterior Part of the Third Ventricle. 2870 38

Chordoid glioma is a rare and relatively recently defined tumour entity. Worldwide there have only been around 90 cases described until now. A chordoid glioma comprises a low-grade suprasellar neuroepithelial neoplasm originating in the anterior part of the third ventricle, with consistent radiological features on MRI. This lesion should be considered as a differential of third ventricle tumours. The patient described in this paper is quite unique in the sense that despite only partial tumour resection was obtained, the residual tumour was not progressive during several years of follow-up. Preoperative recognition of this disease entity is crucial to modify the treatment approach and improve patient outcome.
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PMID:Chordoid Glioma as a Differential Diagnosis of Anterior Third Ventricle Tumours: A Rare Case Report and Five-Year Follow-Up. 3187 14

Chordoid glioma (CG), which often originated from the third ventricle, was a type of rare and slowly growing low grade glioma with chordoid appearance. So far, concurrent occurrence of third ventricule chordoid gliomas with Rosai-Dorfman disease (RDD) has never been observed. In this study, the clinical features, pathological characteristics as well as their prognosis of two CG with RDD component cases were discussed. Herein, we reported two cases of CG with RDD component from a 45-year-old female and a 38-year-old male respectively. Radiologically, the two lesions were located on the region of suprasellar-third ventricular with homogenous contrast enhancement. They underwent gross total resection and remained free of disease progress till now. Microscopically, both lesions showed the classic morphology of CG and RDD component. A morphologic curiosity is presented in tumors manifested by CG with RDD component in the suprasellar-third ventricular region. To the best of our knowledge, this is the first presentation of two collision tumors consisting of CG and RDD on the suprasellar-third ventricular region. Awareness of this entity is important to distinguish it from other CGs. More examples and a timely follow-up are required for understanding the biological features of these cases.
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PMID:Concurrence of chordoid gliomas with Rosai-Dorfman component: report of two rare cases. 3196 79


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