Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0017638 (glioma)
30,880 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Two cases are reported in which a cerebral glioma developed after radiation therapy for a different primary tumor. The first case was a boy, who presented a right thalamic anaplastic astrocytoma 7 years after irradiation for a left temporal polymorphic cell sarcoma. The second case was a woman, with a right temporal anaplastic astrocytoma occurring 8 years after irradiation for a GH-secreting pituitary adenoma. Thirty-five other cases of radiation-associated cerebral gliomas had already been reported in the literature. The possible causal role of radiation therapy in inducing cerebral gliomas is discussed on the basis of these observations.
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PMID:Radiation-associated cerebral gliomas. A report of two cases and review of the literature. 269 30