Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0017638 (glioma)
 30,880 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In this report we describe a patient with a benign glioma treated with surgery and radiation. After a period of stability he developed subacute bacterial endocarditis, and deteriorated neurologically. Computed tomographic scans did not show recurrent tumor. An angiogram showed vasculitis restricted to the previously irradiated area. Secondary to subacute bacterial endocarditis was the presence of high levels of circulating immune complexes. His neurological status was unchanged after antibiotics, but improved after treatment with dexamethasone. We interpret the clinical course as an immune-complex-mediated vasculitis superimposed on a subclinical radiation vasculitis. This case supports the hypothesis that immune mechanisms may be involved in delayed radiation injury to the nervous system.
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PMID:Focal cerebral vasculitis associated with circulating immune complexes and brain irradiation. 372 12

Infectious endocarditis is defined as an infection of the endocardial surface area of the heart which can include one or more cardiac valves, mural endocardium or a septal defect. We present the case of a patient, aged 8, hospitalized in Hemato-Oncology Department with pontine glioma, who was also diagnosed with infectious endocarditis in five locations.
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PMID:Infectious endocarditis with five localisations--case reports. 2474 80