Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0017636 (glioblastoma)
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Human Gene/Protein
MEOX2 protein 10.8
Chitinase 3-like 2 10.8
Neuron navigator 3 10.8
PLOD2 protein 10.8
RGM domain family, member A 10.8
Paraneoplastic cerebellar degeneration-associated antigen 10.8
Lipoma HMGIC fusion partner-like 3 10.8
ZNF226 10.8
RAG cohort 1, importin alpha 1 10.8
KDEL (Lys-Asp-Glu-Leu) containing 2 10.8
UGCGL2 10.8
FAM126B 10.8
LYAM1 10.8
Ring finger protein 135 10.8
TMSL8 10.8
DKFZp762B245 10.8
SNF2 histone linker PHD RING helicase 10.8
atlastin 3 10.8
ATXN7L4 10.8
MLF1IP protein 10.8
HEAT repeat containing 1 10.8
Zinc finger protein 554 10.8
HERC2P2 10.8
SPANXE 10.8
Ku70-binding protein 3 10.3
PHD finger protein 20 10.2
60S ribosomal protein L37 9.8
CTRP8 9.8
pleckstrin homology domain interacting protein 9.8
Src homology 3 domain-containing guanine nucleotide exchange factor 9.8
C1q/TNF-related protein 8 9.8
IL15 protein 9.8
Tripartite motif-containing protein 45 9.8
LRRC46 9.8
tripartite motif-containing 48 9.8
P4HA2 protein 9.8
TMEM167A 9.8
Fibroblast growth factor 13 9.8
ADPRTL2 9.8
THAP3 9.8
XRCC6BP1 9.8
SH3 domain-binding glutamic acid-rich-like protein 3 9.8
transcription factor-like 5 9.8
MUTY 9.8
transmembrane protein 93 9.8
WD repeat domain 12 9.8
DNA (Cytosine-5-)-methyltransferase 1 9.8
Kallikrein 8 9.8
NLRP13 9.8
TANK protein 9.8
E3 ubiquitin ligase SMURF1 9.8
ELTD1 9.6
MAGE-E1 9.4
FNBP3 9.4
IDH1 protein 9.3
SNED1 9.2
GNG3 9.2
ATAD2B 9.2
YIPF1 9.2
SLITRK3 9.2
DNAJC9 9.2
IIp45 9.2
cytochrome c oxidase subunit VIa polypeptide 1 9.2
CENTG1 9.2
FETA 9.2
TSGA13 9.2
C7orf31 9.2
Alpha thalassemia/mental retardation syndrome X-linked 9.2
protocadherin 18 9.2
low density lipoprotein-related protein 1 9.2
ERBB4 protein 9.2
MGC13061 9.2
ZSWIM5 9.2
ACCN2 9.2
PTDSR 9.2
SETMAR protein 9.2
FBXO16 9.2
Tumor suppressor candidate 4 9.2
ATXN7L1 9.2
MRPL35 9.2
more...
Disease
Pineal germinoma 10.8
Glioblastoma 10.8
glioblastoma 10.8
Primitive polar spongioblastoma 10.8
Gliosarcoma 9.9
Diffuse astrocytoma 9.9
lymphoma; leukemia 9.8
childhood cerebellar astrocytoma 9.8
Anaplastic oligoastrocytoma 9.8
Pilocytic Astrocytoma 9.8
Small cell glioblastoma 9.8
Diffuse Astrocytoma 9.8
Anaplastic Astrocytoma 9.8
Primary Brain Tumors 9.8
adult glioblastoma 9.7
adult brain tumor 9.6
Gemistocytic astrocytoma 9.4
giant cell glioblastoma 9.3
anaplastic astrocytoma 9.3
Modified measles 9.2
brain cancer 8.7
brain tumor 8.5
pediatric anaplastic astrocytoma 8.4
gliosarcoma 8.4
oligodendroglioma 8.4
glioblastoma multiforme 8.2
adult astrocytic tumors 8.2
Pleomorphic xanthoastrocytoma 8.1
glioma 8.1
Malignant glioma 8.0
Gliomatosis Cerebri 8.0
Clear cell ependymoma 8.0
MGCT 8.0
astrocytoma 8.0
Turcot syndrome 7.9
oligodendroglial tumor 7.9
Anaplastic oligodendroglioma 7.9
Oligodendroglioma 7.7
Astroblastoma 7.6
Gliomatosis cerebri 7.5
ATRX 7.5
cerebral cancer 7.4
ependymal tumors 7.4
CPHD 7.3
CPHD 7.3
Necrotic tumor 7.3
CPHD 7.3
Ganglioglioma 7.2
CNS tumors 7.2
brain stem glioma 7.1
CNS cancer 7.1
Gopalan 7.1
SCCH 7.1
Central nervous system lymphoma 7.1
ADLTE 7.1
Astroblastoma 7.0
Pilocytic astrocytoma 6.9
pineoblastoma 6.9
intracranial tumors 6.9
medulloblastoma 6.8
FDD 6.8
pituitary cancer 6.8
mixed gliomas 6.8
ependymoma 6.8
ganglioglioma 6.8
grade II meningioma 6.8
cerebral neoplasm 6.7
brain stem tumor 6.6
PNET 6.6
psychological shock 6.5
Membranous lipodystrophy 6.4
monosomy 22 6.3
squamous cell carcinoma of the gallbladder 6.3
primitive neuroectodermal tumor 6.3
Subependymal giant cell astrocytoma 6.3
pineocytoma 6.2
pituitary chromophobe adenoma 6.2
CARASIL 6.2
PNET 6.2
primitive neuroectodermal tumor 6.2
more...
Symptom
gustatory hallucination 8.8
Chronic intractable pain 7.8
gumma 4.3
HSA 3.9
facial droop 3.8
Scratch 3.7
Signs and Symptoms 3.6
frequent urination 3.3
partial seizure 3.3
Flare 3.3
eye pain 3.2
Noise-induced hearing loss 3.1
asterixis 3.1
inanition 3.0
consciousness disturbance 2.7
ataxic gait 2.7
non-productive cough 2.6
Psychiatric symptoms 2.4
tonic-clonic seizure 2.4
meningism 2.4
testicular pain 2.3
blurred vision 2.1
dysarthria 2.1
general problem 2.0
hemiplegia 2.0
orthopnea 1.9
headache 1.9
dry skin 1.8
lightheadedness 1.8
numbness 1.7
hyperesthesia 1.7
paraparesis 1.7
ketonuria 1.7
neck stiffness 1.5
seizures 1.5
leg edema 1.4
CSR 1.3
nausea 1.2
vomiting 1.2
exhaustion 1.2
starvation 1.2
nausea and vomiting 1.1
rigors 1.1
paresis 1.1
ataxia 1.0
memory loss 0.9
weakness 0.8
neck pain 0.8
eds 0.7
catatonia 0.6
ophthalmoplegia 0.6
productive cough 0.6
abnormal gait 0.6
dental pain 0.5
dizziness 0.5
collapse 0.5
masculinization 0.4
fasciculation 0.4
asthenia 0.4
chills 0.3
lethargy 0.3
anosmia 0.2
anorexia 0.2
photophobia 0.1
sleepiness 0.1
torticollis 0.1
fatigue 0.1
hypocapnia 0.0
constipation 0.0
neuralgia -0.0
vertigo -0.0
spasm -0.1
Ill -0.1
chronic cough -0.2
flushing -0.3
skin irritation -0.3
acidity -0.3
diarrhea -0.4
back pain -0.5
paresthesia -0.5
more...
Drug
Gliadel 8.6
Temodal 8.6
Willardiine 8.4
Cilengitide 8.2
Efaproxiral 7.8
Avasimibe 7.8
Ifex 7.8
Penfluridol 7.7
Vatalanib 7.3
Carmofur 7.1
Rilutek 7.0
Bevacizumab 6.9
Tracrium 6.9
Tracrium 6.9
Fotemustine 6.7
Tacalcitol 6.6
Oncophage 6.6
Lonafarnib 6.6
Ilomastat 6.5
Leucin 6.4
Epothilone B 6.2
Calcium citrate 6.2
Cinnamon bark 6.1
Fluspirilene 6.1
Urso 6.1
Ciglitazone 6.1
Motexafin gadolinium 6.1
Axitinib 6.0
Sodium ascorbate 6.0
Ibudilast 5.9
Vorinostat 5.9
Monastrol 5.9
Vandetanib 5.7
Nexavar 5.6
PDGF B-chain 5.6
E5564 5.6
Ceredase 5.6
Ethylene Glycol 5.6
Azilect 5.4
NVP 5.4
Demeclocycline 5.3
Amlexanox 5.3
Irinotecan 5.3
Valganciclovir 5.3
Valproic Acid 5.2
Regadenoson 5.2
Venofer 5.2
Cerezyme 5.1
Onconase 5.0
Parecoxib 5.0
Romidepsin 4.9
Dutasteride 4.9
Erlotinib 4.9
Perhexiline 4.9
ALA 4.9
Folic Acid 4.8
Bisacodyl 4.8
CDX 4.8
Anafranil 4.7
Esculin 4.7
Photofrin II 4.7
Keppra 4.7
Hyperforin 4.7
Radicicol 4.7
Tipifarnib 4.6
Zebularine 4.6
Verteporfin 4.6
Chymopapain 4.6
Marimastat 4.6
Gabexate mesilate 4.5
Dasatinib 4.5
Rasagiline 4.5
Gallium nitrate 4.5
CET 4.4
Propentofylline 4.4
Panitumumab 4.4
Ixabepilone 4.4
Tolfenamic acid 4.4
Gefitinib 4.3
CDX 4.3
more...
Enzyme
triphosphate-protein phosphotransferase 10.8
aspartate beta-hydroxylase 8.4
MIPP 7.7
microtubule-severing ATPase 7.4
gamma-glutamylcyclotransferase 6.8
SOAT 6.7
KGOR 6.3
matrix metalloproteinase 14 6.3
isocitrate dehydrogenase 6.3
isocitrate dehydrogenase 6.1
GalNAc4S-6ST 6.1
PLP phosphatase 6.0
HK3 6.0
phosphoethanolamine cytidylyltransferase 5.8
coagulation factor XIa 5.5
methylthioadenosine phosphorylase 5.5
nicotinamide adenine dinucleotide glycohydrolase 5.4
chondroitin synthase 5.3
cholesterol 25-hydroxylase 5.3
cytosine deaminase 5.2
GD3 synthase 5.2
uracil phosphoribosyltransferase 5.1
site-1 protease 5.0
serum carnosinase 4.9
phosphoinositide 5-phosphatase 4.9
DNA methyltransferase 4.9
GTI 4.9
carnosinase 4.8
HK2 4.8
aggrecanase-1 4.8
nardilysin 4.8
3-hydroxyanthranilic acid oxygenase 4.8
GSase 4.8
aspartoacylase 4.8
deoxyhypusine hydroxylase 4.7
DNA ligase 4.6
DNA ligase 4.6
nicotinamide phosphoribosyltransferase 4.5
EC 4.4.1.5 4.5
adamalysin 4.5
eEF2 kinase 4.5
histone demethylase 4.5
3-mercaptopyruvate sulfurtransferase 4.5
N-acetylglucosaminyltransferase V 4.4
PDK1 4.4
methioninase 4.4
3'-phosphatase 4.4
ERK 4.3
STK3 4.3
EC 2.4.99.1 4.3
CGT 4.3
phosphoinositide 3-kinase 4.3
thymidine kinase 4.3
polypeptide N-acetylgalactosaminyltransferase 4.2
nicotinamide N-methyltransferase 4.2
cathepsin B 4.2
kynurenine 3-monooxygenase 4.2
kynureninase 4.2
N-acetylglucosaminyltransferase III 4.2
glucosylceramide synthase 4.2
serine racemase 4.2
PARP 4.2
caspase-8 4.1
N-acetylglucosaminyltransferase I 4.1
phosphatidylinositol-4,5-bisphosphate 3-kinase 4.1
polo-like kinase 1 4.1
poly(ADP-ribose) glycohydrolase 4.1
MMP 4.0
chlorophyllase 4.0
ceramide kinase 4.0
indoleamine 2,3-dioxygenase 4.0
matrix metalloproteinase 2 4.0
GalNAc-T 4.0
site-1 protease 4.0
caspase-9 4.0
phosphofructokinase 1 3.9
inositol 3-kinase 3.9
alpha-N-acetylglucosaminidase 3.9
CTP synthase 3.8
caspase-3 3.8
more...
Compound
Cinerubin B 10.8
Maculine 10.8
(S)-2,3-Epoxysqualene 9.8
4-(methylsulfonyl)benzaldehyde 9.8
Iridin 9.8
Temozolomide 9.2
Isophosphoramide mustard 9.2
Napelline 9.2
C12H15NO4 9.2
1,7-heptanediamine 9.2
Cirsilineol 8.4
Tigogenin 8.4
BMS 204352 8.4
C10H7NO2 8.4
Harmine hydrochloride 8.4
4-phenylquinazoline 8.2
Willardiine 8.2
NHU 8.2
Clemizole 8.0
Voacangine 8.0
3-furoic acid 8.0
Manool 7.8
BG 1 7.8
D-Tyrosine 7.6
ACNU 7.6
Euxanthone 7.3
Euphol 7.3
tris(4-methoxyphenyl)phosphine 7.3
Propane sultone 7.3
Phenylacetylglutamine 7.3
LNT 7.3
Caprin 7.2
BSH 7.1
2-methyl-1H-benzimidazole 7.1
4-iodobenzamide 7.0
O6-Methylguanine 6.9
2-methylpentanoic acid 6.9
Lucanthone 6.8
2-phenylpyrrolidine 6.8
Petunidin 6.8
Perillyl alcohol 6.7
Perillyl alcohol 6.7
BCNU 6.6
2-methyl-2-cyclohexen-1-one 6.6
MCNU 6.5
Dehydrocostus lactone 6.5
Cedrol 6.5
1,3-thiazolidine-2-thione 6.4
Tubulozole 6.4
Triacetin 6.4
Antineoplaston A10 6.3
A-7 6.3
hydroxyglutarate 6.2
Epothilone B 6.2
Estramustine 6.2
Magnoflorine 6.2
Chlorophyllide 6.2
1,3-thiazolidine-2-thione 6.2
cyclopropanecarboxamide 6.2
Poly ICLC 6.1
2-hydroxy-3-methoxybenzaldehyde 6.1
7-oxabicyclo[2.2.1]heptane 6.1
CCNU 6.0
2-hydroxy-3-methoxybenzaldehyde 6.0
Lanatoside C 6.0
Alantolactone 6.0
bis(2-chloroethyl) 6.0
Luliconazole 6.0
LLY 6.0
Actinonin 6.0
Versene 6.0
Falcarindiol 6.0
Azodicarbonamide 6.0
Phenethyl isothiocyanate 5.9
2-ethoxy-2-oxoethyl 5.9
Isoalantolactone 5.9
Asiatic acid 5.9
bis(2-chloroethyl) 5.9
4-methylquinazoline 5.9
Morusin 5.9
more...