Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0017636 (glioblastoma)
18,345 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein Mol 1422 Sep 1095 p53 1015 EGFR 545 epidermal growth factor receptor 524 methylguanine-DNA methyltransferase 493 MRI 482 vascular endothelial growth factor 397 PTEN 391 AKT 366 caspase-3 365 PI3K 362 GBM 344 mTOR 336 glial fibrillary acidic protein 330 CD133 316 IDH1 298 cytokine 263 Bcl-2 262 VEGF 257 tyrosine kinase 252 ERK 221 IDH 210 MAPK 207 STAT3 196 p21 179 histone 178 catenin 175 NMR 160 ATP 152 ERK1 152 receptor tyrosine kinase 149 matrix metalloproteinase 147 tumor necrosis factor 145 isocitrate dehydrogenase 137 interferon 132 methyltransferase 128 isocitrate dehydrogenase 1 127 endoplasmic reticulum 126 collagen 125 phosphatase 124 epidermal growth factor 123 Ki-67 119 PARP 116 vimentin 116 MMP-2 115 CD44 114 EGF 114 cyclin D1 114 p38 111 CD8 110 fibronectin 109 IL-6 106 ACS 103 PEG 103 UTR 102 VEGFR2 100 nestin 99 BRAF 98 p16 98 proteasome 97 histone deacetylase 97 annexin V 95 cytochrome c 94 survivin 93 MMP-9 93 SOX2 93 platelet-derived growth factor 92 CDKN2A 92 caspase-8 90 JNK 90 MET 88 ROS 87 IFN 86 glycoprotein 85 fused 84 Nestin 84 thymidine kinase 83 MDM2 82 DNA methyltransferase 82 more...

Disease glioblastoma 18345 tumor 8956 cancer 7536 glioma 4872 Glioblastoma 2926 brain tumor 2456 glioblastoma multiforme 1602 tumor growth 1266 astrocytoma 1009 tumorigenesis 747 tumor progression 660 brain cancer 520 melanoma 503 breast cancer 492 anaplastic astrocytoma 440 carcinoma 408 neuroblastoma 360 metastases 340 oligodendroglioma 324 medulloblastoma 310 lung cancer 254 adenocarcinoma 249 aggressiveness 238 meningioma 238 leukemia 216 prostate cancer 190 carcinogenesis 172 primary tumor 169 hepatocellular carcinoma 157 ependymoma 147 tumor angiogenesis 146 gliosarcoma 144 colorectal cancer 142 lymphoma 141 herpes simplex 136 colon cancer 131 intracranial tumors 118 cytomegalovirus 118 MCF 118 sarcoma 116 lung carcinoma 111 Alzheimer's disease 110 ovarian cancer 108 squamous cell carcinoma 104 tumor initiation 104 pancreatic cancer 101 solid tumor 100 tumor vasculature 98 non-small cell lung cancer 95 renal cell carcinoma 93 CNS tumors 92 retinoblastoma 82 brain metastases 81 epilepsy 76 thrombocytopenia 71 ATRX 67 schwannoma 66 residual disease 66 ATM 65 primitive neuroectodermal tumor 65 osteosarcoma 65 multiple myeloma 64 multiple sclerosis 61 gastric cancer 61 fibrosarcoma 60 suicide 60 SCID 59 acute myeloid leukemia 57 primitive neuroectodermal tumor 57 HIV 56 aggression 55 stroke 54 hydrocephalus 53 hypertension 52 Blocking 52 cervical cancer 50 GSH 47 Gliosarcoma 47 diabetes 46 B-cell lymphoma 46 more...

Symptom seizures 129 headache 119 pain 48 vomiting 43 weakness 39 nausea 32 starvation 32 fatigue 31 diarrhea 26 HSA 26 collapse 23 ataxia 18 anesthesia 18 exhaustion 18 nausea and vomiting 12 numbness 10 anorexia 9 dysarthria 9 hemiplegia 9 sleepiness 8 dizziness 8 paresis 7 acidity 7 constipation 6 Ill 6 dyspnea 5 tremor 5 blurred vision 5 paraparesis 5 back pain 5 agitation 4 tonic-clonic seizure 4 low back pain 4 memory loss 4 lethargy 4 erythema 4 partial seizure 4 vertigo 4 abdominal pain 4 spasm 4 neck pain 4 cough 3 ophthalmoplegia 3 consciousness disturbance 3 Scratch 3 chills 3 flushing 3 chest pain 3 syncope 2 paresthesia 2 tinnitus 2 ataxic gait 2 asthenia 2 insomnia 2 discomfort 2 discomfort 2 masculinization 2 eye pain 2 analgesia 2 cachexia 2 dry skin 2 respiratory distress 2 general problem 2 hypotonia 2 angina 1 apathy 1 CSR 1 photophobia 1 chronic cough 1 anosmia 1 Psychiatric symptoms 1 testicular pain 1 gumma 1 dental pain 1 productive cough 1 torticollis 1 facial droop 1 arthralgia 1 ketonuria 1 spasticity 1 more...

Drug Bevacizumab 123 lysine 112 ROS 86 CSF 81 IL-2 47 ALA 47 IFN-gamma 43 ascorbate 31 NVP 24 Monit 22 uPA 21 p75 20 Taxol 20 Imatinib 19 IFN-beta 19 Irinotecan 18 CPT-11 17 ABC 17 MRC 16 L-tyrosine 15 Gliadel 15 MAP 15 Gefitinib 14 GEO 14 Gleevec 14 Erlotinib 13 ROC 13 Glutathione 13 Cilengitide 12 Etoposide 12 Vorinostat 12 citric acid 12 Paraffin 11 CAM 11 G-CSF 11 NADH 11 CTX 11 Gel 11 Temodal 10 caffeine 10 vitamin E 10 Arsenic trioxide 10 TTC 9 ETS 9 Gelatin 9 Dermatol 8 G418 8 Sorafenib 8 FAD 8 Dasatinib 8 Adriamycin 6 Spectrum 6 Nitric Oxide 6 ADM 6 TAT 6 DPA 6 RFP 6 Penfluridol 6 Retinoic acid 6 CTX 6 Bortezomib 6 CTX 6 Asn 5 Cetuximab 5 Simvastatin 5 CTC 5 PDGF B-chain 5 PTC 5 Axitinib 5 Parkin 5 Photofrin 5 Heme 5 Parkin 5 ZnO 5 CTC 5 Fluorescein 5 DNase I 5 Zoledronic acid 4 Photofrin II 4 Mutagen 4 more...

Enzyme ERK 1120 mitogen-activated protein kinase 554 caspase-3 280 luciferase 265 focal adhesion kinase 260 protein kinase 215 PARP 140 isocitrate dehydrogenase 139 isocitrate dehydrogenase 137 protein kinase C 108 ACS 104 MEK 101 proteasome 99 DNA methyltransferase 84 thymidine kinase 83 phosphatidylinositol 3-kinase 75 urokinase-type plasminogen activator 74 P-glycoprotein 73 caspase-8 69 caspase-9 67 phosphoinositide 3-kinase 66 AMP-activated protein kinase 62 reverse transcriptase 61 topoisomerase 47 calcineurin 46 cathepsin B 44 topoisomerase 44 AMPK 43 cdc2 42 AMPK 40 MMP 40 DNA ligase 39 DNA ligase 39 ATPase 38 catalase 37 GSK 36 superoxide dismutase 36 lactate dehydrogenase 34 trypsin 30 thrombin 29 peroxidase 29 phospholipase C 29 PDK1 28 RNA polymerase 27 collagenase 23 APC 23 glutathione S-transferase 22 RNase 21 RNase 21 matrix metalloproteinase 2 21 demethylase 20 glyceraldehyde-3-phosphate dehydrogenase 19 beta-galactosidase 18 plasmin 18 transcriptase 18 endonuclease 18 glutathione peroxidase 18 chloramphenicol acetyltransferase 17 firefly luciferase 17 ribonucleotide reductase 17 alkaline phosphatase 17 cytosine deaminase 16 ribonucleotide reductase 16 complex I 16 polo-like kinase 1 15 IKK 15 pyruvate kinase 14 alanine aminotransferase 14 phosphodiesterase 14 carbonic anhydrase 14 indoleamine 2,3-dioxygenase 13 5'-nucleotidase 12 aldehyde dehydrogenase 12 histone demethylase 12 aldehyde dehydrogenase 12 aldehyde dehydrogenase 12 aldehyde dehydrogenase 12 aldehyde dehydrogenase 12 MAP 11 cathepsin D 11 more...

Compound DNA 1925 Dec 1124 Clin 725 oxygen 538 tyrosine 310 MTT 289 Temozolomide 273 glucose 238 calcium 202 water 184 PEG 170 arginine 162 iron 157 ATP 152 sodium 151 methionine 144 lysine 137 BCNU 128 MDA 125 PEG 123 phosphate 122 boron 122 serine 118 cysteine 109 glutamate 106 ACS 104 ACS 103 acetate 88 iodine 84 retinoic acid 81 TNF 78 Asp 77 MEK 74 nitric oxide 72 ACNU 71 threonine 70 sulfate 70 bromide 66 hydrogen 65 cAMP 64 glutamine 62 alanine 60 tryptophan 58 leucine 57 hyaluronic acid 54 GSH 53 GSH 53 zinc 52 Phe 52 tryptophan 51 tryptophan 50 tryptophan 50 Curcumin 46 His 45 urea 44 hydroxyglutarate 42 Adriamycin 42 galactose 40 Gly 39 ADR 39 salt 39 nitrogen 36 bis(2-chloroethyl) 36 CCNU 34 potassium 34 2-oxoglutarate 34 ADP 34 bis(2-chloroethyl) 34 bis(2-chloroethyl) 34 DTPA 33 TOF 33 ASA 33 copper 32 NAD 32 AMP 32 aspartic acid 31 isocitrate 31 pyrimidine 30 ADP 30 pyrimidine 30 more...

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