Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0017636 (glioblastoma)
18,345 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Mol 1422
Sep 1095
p53 1015
EGFR 545
epidermal growth factor receptor 524
methylguanine-DNA methyltransferase 493
MRI 482
vascular endothelial growth factor 397
PTEN 391
AKT 366
caspase-3 365
PI3K 362
GBM 344
mTOR 336
glial fibrillary acidic protein 330
CD133 316
IDH1 298
cytokine 263
Bcl-2 262
VEGF 257
tyrosine kinase 252
ERK 221
IDH 210
MAPK 207
STAT3 196
p21 179
histone 178
catenin 175
NMR 160
ATP 152
ERK1 152
receptor tyrosine kinase 149
matrix metalloproteinase 147
tumor necrosis factor 145
isocitrate dehydrogenase 137
interferon 132
methyltransferase 128
isocitrate dehydrogenase 1 127
endoplasmic reticulum 126
collagen 125
more...
Disease
glioblastoma 18345
tumor 8956
cancer 7536
glioma 4872
Glioblastoma 2926
brain tumor 2456
glioblastoma multiforme 1602
tumor growth 1266
astrocytoma 1009
tumorigenesis 747
tumor progression 660
brain cancer 520
melanoma 503
breast cancer 492
anaplastic astrocytoma 440
carcinoma 408
neuroblastoma 360
metastases 340
oligodendroglioma 324
medulloblastoma 310
lung cancer 254
adenocarcinoma 249
aggressiveness 238
meningioma 238
leukemia 216
prostate cancer 190
carcinogenesis 172
primary tumor 169
hepatocellular carcinoma 157
ependymoma 147
tumor angiogenesis 146
gliosarcoma 144
colorectal cancer 142
lymphoma 141
herpes simplex 136
colon cancer 131
intracranial tumors 118
cytomegalovirus 118
MCF 118
sarcoma 116
more...
Symptom
seizures 129
headache 119
pain 48
vomiting 43
weakness 39
nausea 32
starvation 32
fatigue 31
HSA 26
diarrhea 26
collapse 23
ataxia 18
anesthesia 18
exhaustion 18
nausea and vomiting 12
numbness 10
anorexia 9
dysarthria 9
hemiplegia 9
dizziness 8
sleepiness 8
paresis 7
acidity 7
Ill 6
constipation 6
dyspnea 5
paraparesis 5
blurred vision 5
back pain 5
tremor 5
neck pain 4
tonic-clonic seizure 4
partial seizure 4
vertigo 4
erythema 4
abdominal pain 4
lethargy 4
memory loss 4
agitation 4
spasm 4
more...
Drug
Bevacizumab 123
lysine 112
ROS 86
CSF 81
ALA 47
IL-2 47
IFN-gamma 43
ascorbate 31
NVP 24
Monit 22
uPA 21
p75 20
Taxol 20
Imatinib 19
IFN-beta 19
Irinotecan 18
CPT-11 17
ABC 17
MRC 16
L-tyrosine 15
MAP 15
Gliadel 15
Gleevec 14
GEO 14
Gefitinib 14
Glutathione 13
ROC 13
Erlotinib 13
Vorinostat 12
Cilengitide 12
Etoposide 12
citric acid 12
G-CSF 11
NADH 11
Gel 11
Paraffin 11
CTX 11
CAM 11
Temodal 10
caffeine 10
more...
Enzyme
ERK 1120
mitogen-activated protein kinase 554
caspase-3 280
luciferase 265
focal adhesion kinase 260
protein kinase 215
PARP 140
isocitrate dehydrogenase 139
isocitrate dehydrogenase 137
protein kinase C 108
ACS 104
MEK 101
proteasome 99
DNA methyltransferase 84
thymidine kinase 83
phosphatidylinositol 3-kinase 75
urokinase-type plasminogen activator 74
P-glycoprotein 73
caspase-8 69
caspase-9 67
phosphoinositide 3-kinase 66
AMP-activated protein kinase 62
reverse transcriptase 61
topoisomerase 47
calcineurin 46
topoisomerase 44
cathepsin B 44
AMPK 43
cdc2 42
AMPK 40
MMP 40
DNA ligase 39
DNA ligase 39
ATPase 38
catalase 37
superoxide dismutase 36
GSK 36
lactate dehydrogenase 34
trypsin 30
thrombin 29
more...
Compound
DNA 1925
Dec 1124
Clin 725
oxygen 538
tyrosine 310
MTT 289
Temozolomide 273
glucose 238
calcium 202
water 184
PEG 170
arginine 162
iron 157
ATP 152
sodium 151
methionine 144
lysine 137
BCNU 128
MDA 125
PEG 123
boron 122
phosphate 122
serine 118
cysteine 109
glutamate 106
ACS 104
ACS 103
acetate 88
iodine 84
retinoic acid 81
TNF 78
Asp 77
MEK 74
nitric oxide 72
ACNU 71
sulfate 70
threonine 70
bromide 66
hydrogen 65
cAMP 64
more...