Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0017636 (
glioblastoma
)
18,345
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Mol
1422
Sep
1095
p53
1015
EGFR
545
epidermal growth factor receptor
524
methylguanine-DNA methyltransferase
493
MRI
482
vascular endothelial growth factor
397
PTEN
391
AKT
366
caspase-3
365
PI3K
362
GBM
344
mTOR
336
glial fibrillary acidic protein
330
CD133
316
IDH1
298
cytokine
263
Bcl-2
262
VEGF
257
tyrosine kinase
252
ERK
221
IDH
210
MAPK
207
STAT3
196
p21
179
histone
178
catenin
175
NMR
160
ATP
152
ERK1
152
receptor tyrosine kinase
149
matrix metalloproteinase
147
tumor necrosis factor
145
isocitrate dehydrogenase
137
interferon
132
methyltransferase
128
isocitrate dehydrogenase 1
127
endoplasmic reticulum
126
collagen
125
more...
Disease
glioblastoma
18345
tumor
8956
cancer
7536
glioma
4872
Glioblastoma
2926
brain tumor
2456
glioblastoma multiforme
1602
tumor growth
1266
astrocytoma
1009
tumorigenesis
747
tumor progression
660
brain cancer
520
melanoma
503
breast cancer
492
anaplastic astrocytoma
440
carcinoma
408
neuroblastoma
360
metastases
340
oligodendroglioma
324
medulloblastoma
310
lung cancer
254
adenocarcinoma
249
aggressiveness
238
meningioma
238
leukemia
216
prostate cancer
190
carcinogenesis
172
primary tumor
169
hepatocellular carcinoma
157
ependymoma
147
tumor angiogenesis
146
gliosarcoma
144
colorectal cancer
142
lymphoma
141
herpes simplex
136
colon cancer
131
intracranial tumors
118
cytomegalovirus
118
MCF
118
sarcoma
116
more...
Symptom
seizures
129
headache
119
pain
48
vomiting
43
weakness
39
nausea
32
starvation
32
fatigue
31
HSA
26
diarrhea
26
collapse
23
ataxia
18
anesthesia
18
exhaustion
18
nausea and vomiting
12
numbness
10
anorexia
9
dysarthria
9
hemiplegia
9
dizziness
8
sleepiness
8
paresis
7
acidity
7
Ill
6
constipation
6
dyspnea
5
paraparesis
5
blurred vision
5
back pain
5
tremor
5
neck pain
4
tonic-clonic seizure
4
partial seizure
4
vertigo
4
erythema
4
abdominal pain
4
lethargy
4
memory loss
4
agitation
4
spasm
4
more...
Drug
Bevacizumab
123
lysine
112
ROS
86
CSF
81
ALA
47
IL-2
47
IFN-gamma
43
ascorbate
31
NVP
24
Monit
22
uPA
21
p75
20
Taxol
20
Imatinib
19
IFN-beta
19
Irinotecan
18
CPT-11
17
ABC
17
MRC
16
L-tyrosine
15
MAP
15
Gliadel
15
Gleevec
14
GEO
14
Gefitinib
14
Glutathione
13
ROC
13
Erlotinib
13
Vorinostat
12
Cilengitide
12
Etoposide
12
citric acid
12
G-CSF
11
NADH
11
Gel
11
Paraffin
11
CTX
11
CAM
11
Temodal
10
caffeine
10
more...
Enzyme
ERK
1120
mitogen-activated protein kinase
554
caspase-3
280
luciferase
265
focal adhesion kinase
260
protein kinase
215
PARP
140
isocitrate dehydrogenase
139
isocitrate dehydrogenase
137
protein kinase C
108
ACS
104
MEK
101
proteasome
99
DNA methyltransferase
84
thymidine kinase
83
phosphatidylinositol 3-kinase
75
urokinase-type plasminogen activator
74
P-glycoprotein
73
caspase-8
69
caspase-9
67
phosphoinositide 3-kinase
66
AMP-activated protein kinase
62
reverse transcriptase
61
topoisomerase
47
calcineurin
46
topoisomerase
44
cathepsin B
44
AMPK
43
cdc2
42
AMPK
40
MMP
40
DNA ligase
39
DNA ligase
39
ATPase
38
catalase
37
superoxide dismutase
36
GSK
36
lactate dehydrogenase
34
trypsin
30
thrombin
29
more...
Compound
DNA
1925
Dec
1124
Clin
725
oxygen
538
tyrosine
310
MTT
289
Temozolomide
273
glucose
238
calcium
202
water
184
PEG
170
arginine
162
iron
157
ATP
152
sodium
151
methionine
144
lysine
137
BCNU
128
MDA
125
PEG
123
boron
122
phosphate
122
serine
118
cysteine
109
glutamate
106
ACS
104
ACS
103
acetate
88
iodine
84
retinoic acid
81
TNF
78
Asp
77
MEK
74
nitric oxide
72
ACNU
71
sulfate
70
threonine
70
bromide
66
hydrogen
65
cAMP
64
more...