Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0017636 (glioblastoma)
18,345 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Mol 1422
Sep 1095
p53 1015
EGFR 545
epidermal growth factor receptor 524
methylguanine-DNA methyltransferase 493
MRI 482
vascular endothelial growth factor 397
PTEN 391
AKT 366
caspase-3 365
PI3K 362
GBM 344
mTOR 336
glial fibrillary acidic protein 330
CD133 316
IDH1 298
cytokine 263
Bcl-2 262
VEGF 257
more...
Disease
glioblastoma 18345
tumor 8956
cancer 7536
glioma 4872
Glioblastoma 2926
brain tumor 2456
glioblastoma multiforme 1602
tumor growth 1266
astrocytoma 1009
tumorigenesis 747
tumor progression 660
brain cancer 520
melanoma 503
breast cancer 492
anaplastic astrocytoma 440
carcinoma 408
neuroblastoma 360
metastases 340
oligodendroglioma 324
medulloblastoma 310
more...
Symptom
seizures 129
headache 119
pain 48
vomiting 43
weakness 39
starvation 32
nausea 32
fatigue 31
HSA 26
diarrhea 26
collapse 23
ataxia 18
anesthesia 18
exhaustion 18
nausea and vomiting 12
numbness 10
anorexia 9
hemiplegia 9
dysarthria 9
dizziness 8
more...
Drug
Bevacizumab 123
lysine 112
ROS 86
CSF 81
ALA 47
IL-2 47
IFN-gamma 43
ascorbate 31
NVP 24
Monit 22
uPA 21
Taxol 20
p75 20
IFN-beta 19
Imatinib 19
Irinotecan 18
CPT-11 17
ABC 17
MRC 16
MAP 15
more...
Enzyme
ERK 1120
mitogen-activated protein kinase 554
caspase-3 280
luciferase 265
focal adhesion kinase 260
protein kinase 215
PARP 140
isocitrate dehydrogenase 139
isocitrate dehydrogenase 137
protein kinase C 108
ACS 104
MEK 101
proteasome 99
DNA methyltransferase 84
thymidine kinase 83
phosphatidylinositol 3-kinase 75
urokinase-type plasminogen activator 74
P-glycoprotein 73
caspase-8 69
caspase-9 67
more...
Compound
DNA 1925
Dec 1124
Clin 725
oxygen 538
tyrosine 310
MTT 289
Temozolomide 273
glucose 238
calcium 202
water 184
PEG 170
arginine 162
iron 157
ATP 152
sodium 151
methionine 144
lysine 137
BCNU 128
MDA 125
PEG 123
more...