Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0017636 (
glioblastoma
)
18,345
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Extracranial spread from a
glioblastoma
is rare. We present a case of a 48year-old man with a previously radiologically-stable left temporal lobe
glioblastoma
presenting with symptoms referrable to the spinal cord. MRI revealed a spinal cord lesion, with the differential including transverse
myelitis
and tumour. Open surgical biopsy revealed high-grade astrocytoma. Genetic analysis of both the supratentorial and spinal tumours revealed R132H IDH1 mutations, providing evidence that the spinal cord lesion had spread from the supratentorial tumour.
...
PMID:Distant spread of a supratentorial glioblastoma to the spinal cord. 2808 18
