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Query: UMLS:C0017636 (glioblastoma)
 18,345 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

OBJECTIVE The purpose of this study was to describe a method of resecting temporal gliomas through a keyhole lobectomy and to share the results of using this technique. METHODS The authors performed a retrospective review of data obtained in all patients in whom the senior author performed resection of temporal gliomas between 2012 and 2015. The authors describe their technique for resecting dominant and nondominant gliomas, using both awake and asleep keyhole craniotomy techniques. RESULTS Fifty-two patients were included in the study. Twenty-six patients (50%) had not received prior surgery. Seventeen patients (33%) were diagnosed with WHO Grade II/III tumors, and 35 patients (67%) were diagnosed with a glioblastoma. Thirty tumors were left sided (58%). Thirty procedures (58%) were performed while the patient was awake. The median extent of resection was 95%, and at least 90% of the tumor was resected in 35 cases (67%). Five of 49 patients (10%) with clinical follow-up experienced permanent deficits, including 3 patients (6%) with hydrocephalus requiring placement of a ventriculoperitoneal shunt and 2 patients (4%) with weakness. Three patients experienced early postoperative anomia, but no patients had a new speech deficit at clinical follow-up. CONCLUSIONS The authors provide their experience using a keyhole lobectomy for resecting temporal gliomas. Their data demonstrate the feasibility of using less invasive techniques to safely and aggressively treat these tumors.
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PMID:Method for temporal keyhole lobectomies in resection of low- and high-grade gliomas. 2868 18

The neurobehavioral syndrome of hemispatial neglect, which can result from insults such as stroke, brain tumor, or head injury, has most frequently been described as occurring for the left-side of hemispace following lesions to the right hemisphere. While right hemispatial neglect/inattention may occur following left hemisphere lesions as well, it has received limited attention in the scientific literature. The present case describes an inpatient neuropsychological evaluation with a 67-year-old, African American man presenting with right hemispatial neglect following resection of a large glioblastoma in the left occipitotemporoparietal region. The evaluation included a clinical interview, neurobehavioral status examination, and a battery of neuropsychological tests. Results documented consistent evidence of right hemispatial neglect across the administered tests, which could not be attributed to an established right visual field cut. Neuropsychological testing also revealed nearly global deficits in complex visuoperception, posterior/receptive language, memory, and complex attention/executive functioning abilities, while basic attention remained intact. Further remarkable findings of this case included color anomia and transcortical sensory aphasia. Findings from the case are discussed in the context of the preexisting literature on hemispatial neglect and the theoretical specialization of the parietal lobe for spatial attention/awareness.
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PMID:Case of right hemispatial neglect and transcortical sensory aphasia following left occipitotemporoparietal glioblastoma resection. 3098 54