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Query: UMLS:C0017536 (giardiasis)
 1,714 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A rural development project carried out in Southern Zimbabwe for 5 years was aimed at improving nutrition, combatting diseases, educating villagers about proper hygiene, improving water quality, and assessing the development and nutritional status of children under 5. The community investigated consisted of 10,000 people or 1,439 families with an average of 7 persons per family. The main staple of their diet was maize, and malnutrition was prevalent. Water holes infested with bilharzia were the source of drinking water for both man and animal. The project succeeded in vaccinating 90% of preschool children against whooping cough, diphtheria, tetanus, polio, measles, and tuberculosis. A control district was chosen to compare the developmental data obtained by the Cole Slide Rule Calculator of 229 children under 5 with those of 242 children in the project. Malnutrition was studied in 200 children hospitalized in the children's ward of a district hospital, 1/3 of whom were less than 1 year old. Gastroenteritis, giardiasis and amebiasis were prevalent among them (37%), as were upper respiratory infections (27%), pneumonia (12%), and skin infections (7%). Nonspecific gastroenteritis was found in 86% of children under 2. Most over 2 were severely undernourished. A nutritional rehabilitation village called Hutano Village was established in 1982 to function as a nutritional center, staffed by a full-time health worker and an assistant. In the 1st 9 months of its existence, 114 children were taken in, and the mothers received instruction in vegetable gardening, raising chickens and rabbits, hygiene, and family planning. The average attendance runs to 25 children and 15 to 17 mothers. In spite of successful medical intervention in malnutrition cases, the relapse of children into an undernourished state remains a difficult issue, whose cause lies in inadequate water supply, poor soil, lack of resources, and low family socio-economic status.
Lakartidningen 1984 Sep 05
PMID:[Improved health in Zimbabwe's rural areas as a result of the rural development project]. 648 96

We made clinical and immunologic observations of 30 children with common variable hypogammaglobulinemia. The mean age at diagnosis was 10.5 years, five years after clinical onset. Diagnosis was initially made based on a history of recurrent otobronchopulmonary infections, diarrhea, or both. The most common complications included short stature, bronchiectasis, and malabsorption, often associated with giardiasis or sprue. Nine patients had associated autoimmune diseases (eg, atrophic gastritis, arthritis, and hemolytic anemia). Three patients died, one of chronic respiratory insufficiency, one of chronic persisting hepatitis, and one of osteogenic sarcoma. Humoral and cellular immune functions of all patients were examined.
Am J Dis Child 1983 Sep
PMID:Common variable hypogammaglobulinemia in children. Clinical and immunologic observations in 30 patients. 660 51

An eight-month survey of patients with gastrointestinal complaints is presented. There were 213 cases collected. Based on stool examinations, Ascaris lumbricoides is still the most common followed by Giardia lamblia and Trichuris trichiura, respectively. From these 213 cases, Giardia was detected in 34 patients. Most of the subjects belong to the older age group between 7-10 years. Anorexia and weight loss are the most common complaints followed by diarrhoea. Based on the duration of complaints, giardiasis is a chronic infection. All 34 subjects were managed with metronidazole at a dose of 40 mg per kg per day in three divided doses for a period of seven days. Cure rate was 100% with no toxicity noted. Metronidazole is therefore suggested as a drug of choice for Giardia lamblia infection.
Southeast Asian J Trop Med Public Health 1982 Sep
PMID:The efficacy of metronidazole in the treatment of giardiasis. 716 51

About three clinics cases, the author points out the presence of urticaria symptoms associated with giardiasis disease, and necessity of the treatment of such parasitosis, after parasitological investigation of motions.
Arch Inst Pasteur Tunis 1980 Sep
PMID:[Skin manifestations of giardiasis. Some clinical cases]. 721 67

An 18-month-old Cavalier King Charles Spaniel with recurrent diarrhoea for 2 months had signs suggesting dysfunction of small and large bowel. No helminth ova, protozoa or fat were found on faecal examination. Proctoscopy, barium enema examination and colonic biopsy revealed mucosal colitis. Biopsied small intestine was histologically normal but Giardia trophozoites were numerous in fluid aspirated from the duodenum. Absorption of d-xylose was normal. Giardiosis and idiopathic colitis were diagnosed. Clinical signs abated after 2 courses of metronidazole administration.
Aust Vet J 1980 Sep
PMID:Giardiosis and colitis in a dog. 745 85

Mb. Whipple is a rare systemic disorder with multiple manifestations. We present a case-story demonstrating the typical course: migrating, non-deforming arthralgies are years later followed by diarrhoea, loss of weight, fatigue and pronounced biochemical disturbances. Intestinal biopsy shows numerous PAS-positive, diastaseresistent macrophages, and antibiotic treatment is initiated. After a somewhat prolonged course, complicated with Giardiasis and endocarditis, the patient recovers. Four months after the cessation of antibiotic treatment, however, the patient shows clinical signs of relapse, and treatment is restarted. The etiological agent has recently been identified as a gram-positive actinomycete called Tropheryma Whippleii. There are some, but not unequivocal, signs of a cellular immunodeficiency, perhaps predestinating certain patients to the disease. The course is usually favourable, when treated with relevant antibiotics. Relapse is not uncommon, and is very problematic when the CNS is involved. Therefore, a combination treatment with good penetration of the blood-brain barrier is recommended--e.g. two weeks treatment with parenterally administered streptomycin and benzylpenicillin followed by sulphamethoxazole-trimethoprim orally for one year.
Ugeskr Laeger 1993 Sep 20
PMID:[Whipple disease. A rare systemic disorder with multiple manifestations]. 750 46

Histological changes in 20 Giardia positive duodenal biopsies (Group A) were compared with 50, Giardia negative duodenal biopsies (Group B), taken during the same period. Stool examinations in Group B were negative for Giardia. Surface epithelium, villous and crypt architecture and cellular infiltrates were examined and compared between the groups. Atrophic changes in the villi were more common in Group A as compared to B(P < 0.0001). Intraepithelial neutrophil infiltration (P < 0.001), infiltration of the lamina propria with plasma cells (P < 0.5), and presence of eosinophils in the lamina propria (P < 0.001) were significant findings in group A. Some of the changes were related to the density of Giardia colonization e.g., the goblet cell depletion (P < 0.05) and the density of plasma cell infiltration in lamina propria (P < 0.01). Erosions and ulcerations were less commonly seen in group A. Thus we conclude that giardiasis manifests its peculiar features in the distal duodenal mucosa and a biopsy of this region is an important diagnostic tool for detection of this disease.
J Pak Med Assoc 1994 Sep
PMID:Peculiar histopathological features of giardiasis in distal duodenal biopsies. 779 7

The inner city population of the Los Angeles county has rapidly become largely Latino. The 3.3 million Latinos living in the county in 1990 had much higher poverty rates and lower educational attainment rates than Anglo (non-Hispanic white) or blacks. The health indicators of the three groups are compared for 1990. In birth outcome, although Latinos were the least likely to receive care in the first trimester, Latinos and Anglos had identical rates of low birth weight babies, and lower rates than blacks. Latino infant mortality was the lowest of the three. The age-adjusted death rates showed that Latinos have a lower overall death rate than Anglos or blacks, and lower specific rates for heart disease, cancer, AIDS and stroke. Latinos did have higher death rates than Anglos for accidents, homicides, cirrhosis and diabetes. Latinos had incidence rates of gonorrhoea and syphilis similar to Anglos and lower than blacks. The communicable disease rates for Latinos was many times higher than Anglos or blacks, including those for measles, shigellosis, giardiasis and hepatitis A. Implications for family medicine are discussed.
Fam Pract 1994 Sep
PMID:Latino health in Los Angeles: family medicine in a changing minority context. 784 24

A case of 26-year-old male patient is presented. He developed a "sprue-like" syndrome, giardiasis and nodular lymphoid hyperplasia of the gastrointestinal tract. After the immunological study, the common variable immunodeficiency diagnosis was established. Pathogenic and diagnosis aspects were analyzed. Therapeutic response was excellent.
Rev Esp Enferm Dig 1994 Sep
PMID:[A patient with gastrointestinal manifestations and the common variable immunodeficiency syndrome]. 798 2

Diagnosing a cause of diarrhea is a challenging undertaking but can be accomplished if a systematic approach is used for evaluation. Pathophysiologic mechanisms of acute diarrhea (eg, Giardia lamblia infection, antibiotic use) are different from those of chronic diarrhea (eg, secretory dysfunction from thyrotoxicosis, lactose or fructose intolerance), so adequate history taking and physical examination are essential in narrowing the diagnosis. Laboratory investigation can then be directed using the information obtained, and the cause of the diarrhea can be established without subjecting the patient to extensive and expensive testing. Undoubtedly, some functional entities that contribute to diarrhea await discovery.
Postgrad Med 1994 Sep 01
PMID:Acute and chronic diarrhea. How to keep laboratory testing to a minimum. 807 13


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