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Query: UMLS:C0017536 (giardiasis)
 1,714 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Giardiasis is a common intestinal infection which commonly presents with nonspecific symptoms. Suspected cases are usually diagnosed by stool examination or duodenal aspirates or biopsies. The purpose of this case report is to alert physicians to the fact that the organism may be present in colonic and ileal biopsies when clinical symptoms prompt a clinician to perform colonic biopsies rather than the usual tests of stools and duodenal aspirates or biopsies.
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PMID:Giardiasis diagnosed by biopsy of the colon and terminal ileum: unusual sites for a common pathogen. 860 29

Giardiasis is the most common protozoan parasite diagnosed in the pathology departments of Health Centres in the State of Bahrain. In 1983 all records of stool parasitology examinations in one of the largest medical centre (Salmaniya Medical Center) were studied, a total of 9664 records. The incidence of Giardia lamblia was 4% (386 cases) of the total records, about 21% of all infected persons by parasites. 100 persons from the above records were serologically examined by CIT with 93% positive results. The incidence of Giardia lamblia amongst the families of infected persons of the 386 cases was higher than the families of non-infected persons.
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PMID:Giardiasis amongst in-and out-patients in Salmaniya Medical Centre in state of Bahrain. 792 84

Giardiasis constitutes a very frequent intestinal parasitic infection in our country, with a varied digestive symptomatology. We performed a prospective, transversal study, with the aim to establish the frequency of G. lamblia in digestive symptomatic patients submitted to upper gastrointestinal endoscopy examination trying to relate its isolation with the endoscopic findings. We studied 50 patients; they were submitted to upper endoscopy examination. During the procedure, we aspirated duodenal content and six duodenal biopsies were taken; 8 to 14 hours before endoscopy, they swallowed the Enterotest encapsulated string. The presence of G. lamblia was established by three methods (Enterotest, duodenal content, impront). The day, of the endoscopic examination they resolved a questionnaire of digestive symptoms they had during the last 4 weeks. The endoscopy was informed like normal in 15 patients. (30%). Duodenitis was detected by endoscopy in 9 patients (18%), but neither one of them demonstrated presence of G. lamblia. By the three diagnostic methods, the presence of G. lamblia was demonstrated in 5 patients (19%), without endoscopic duodenitis, being the digestive symptom scores not statistically significant respect to symptomatic patients without G. lamblia. We concluded that the three diagnostic methods used to identify G. lamblia were equally sensitive. No preponderance of digestive symptoms were present in patients with G. lamblia in relation to in our country patients without G. lamblia infection. We recommend to consider duodenal aspiration during endoscopy in order to discard giardiasis.
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PMID:[The prevalence of giardiasis in patients who undergo gastroduodenoscopy]. 800 25

Ornidazole (Tiberal La Roche) was used in 50 persons infected with Giardia intestinalis in the doses of 500 mg twice a day during 5 days. Examinations were performed after 7-10 days, having been repeated one month and 3 months later. A positive results were achieved after one month in 46 cases (92%) and after 3 months in 45 cases (90%). Tiberal is thought to be effective drug in the treatment of Giardiasis, causing no side effect apart from headache and nausea occurring sporadically.
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PMID:[Observations of the efficacy of ornidazole (Tiberal La Roche) in treatment of giardiasis]. 802 8

Giardiasis is the most common small intestinal protozoal infection and is found worldwide. The mechanisms by which Giardia duodenalis (= G. lamblia) produces chronic diarrhoea and malabsorption have still not been clearly defined. Many infections are associated with mild to moderate mucosal damage which, in animal models of infection, have functional correlates. Possible mechanisms include direct physical injury, release of parasite products such as proteinases or lectin, and mucosal inflammation associated with T cell activation and cytokine release. Other possible mechanisms of malabsorption include associated bacterial overgrowth and bile salt deconjugation, bile salt uptake by the parasite with depletion of intraluminal bile salts, and inhibition of pancreatic hydrolytic enzymes. Thus, there is no single mechanism to explain the diarrhoea and malabsorption caused by Giardia, which currently should be regarded as a multifactorial process.
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PMID:Diarrhoeal disease: current concepts and future challenges. Pathogenesis of giardiasis. 810 43

The case of 28 aged woman with cellular damage of liver is presented. Toxic side-effect of n-propylajmaline was confirmed after exclusion of Viral hepatitis or co-existed poly-parasitism (Ascaridiasis, Giardiasis), as reason of liver injury.
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PMID:[Hepatotoxic side effect of n-propylajmaline suggesting suspicion of viral hepatitis--case history]. 817 Dec 11

Clostridium difficile has been associated with diarrhea in hospitalized patients receiving antibiotic therapy, and may be nosocomially acquired. Rehabilitation hospital inpatients may require frequent antibiotic intervention and are thus at risk, though few reports of epidemics at such centers have been published. This study describes the evaluation and prevalence of C difficile-related disease, among rehabilitation hospital inpatients. A retrospective review was conducted of all diarrhea evaluations performed among inpatients in two freestanding rehabilitation hospitals over a two-year period. A total of 303 laboratory tests were performed among the 115 patients evaluated. C difficile was determined to be the etiologic agent of diarrhea in 25% of patients undergoing enteric evaluation, and in 39% of patients specifically assayed for C difficile toxin B. Giardiasis was detected in one patient, and no evidence of Salmonella, Shigella, Campylobacter, or Yersinia infection was found. The estimated prevalences for diarrhea and C difficile-related disease were 3.7% and 1.1%, respectively. Thus, C difficile is an important cause of diarrhea among rehabilitation hospital inpatients, though its true prevalence may be underestimated due to inadequate diagnostic evaluation. Enteric bacterial pathogens such as Campylobacter, Salmonella, Shigella, Yersinia, and Giardia are insignificant causes of diarrhea among these patients. Elimination of routine testing for these pathogens would reduce costs without compromising diagnostic utility. Diagnostic evaluation should include C difficile toxin assay, and if positive, appropriate therapy instituted.
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PMID:Clostridium difficile-related disease: evaluation and prevalence among inpatients with diarrhea in two freestanding rehabilitation hospitals. 826 89

Giardiasis is the most commonly reported intestinal protozoal infection worldwide, but its relatively long incubation period and often insidious onset make detection of common-source outbreaks difficult. Few well-documented foodborne outbreaks of giardiasis have been reported. In November 1990, such an outbreak among insurance company employees resulted in 18 laboratory-confirmed and 9 suspected cases of giardiasis. A case-control study of 26 ill and 162 well employees implicated raw sliced vegetables served in the employee cafeteria and prepared by a food handler infected with Giardia lamblia as the probable vehicle (odds ratio, 5.1; 95% confidence interval, 1.4-22.7). This outbreak illustrates the potential for transmission of Giardia organisms to occur in commercial establishments through a frequently served food item.
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PMID:Foodborne giardiasis in a corporate office setting. 841 77

This article reviews important intestinal protozoal infections in cats. Among intestinal protozoa, Giardia and coccidia are the most important infections. Giardiasis is a common problem in catteries, especially where young kittens run free on the floor. Overcrowding and high humidity favour the survival and transmission of Giardia. Diagnosis is made by fecal examination by direct or concentration methods. Metronidazole is the drug of choice for treating giardiasis. Among the coccidial parasites, Isospora felis and Cryptosporidium sp. are the common infections. Virtually all cats become infected with Isospora felis. The pathogenicity of I. felis is controversial. Cryptosporidium parvum infection is a zoonosis. Cryptosporidium is transmitted by direct fecal-oral cycle. Cryptosporidial infections appear to be clinical in immunosuppressed cats. No drug has been found satisfactory for treatment of cryptosporidiosis.
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PMID:Intestinal protozoa infections. 842 88

Giardiasis is the most frequently reported diarrheal disease in northern New England. A case-control study of endemic giardiasis and environmental risk factors among residents of New Hampshire involved 273 cases from the state's 1984 disease registry and 375 controls. Giardiasis was associated with a shallow dug well as a residential water source (odds ratio [OR] = 2.4; 95% confidence interval [CI], 1.3-47.0), a recent history of drinking untreated surface water (OR = 3.4; CI, 2.1-5.5), a history of swimming in a lake or pond (OR = 4.6; CI, 2.4-86.0) or swimming in any natural body of fresh water (OR = 4.0; CI, 2.3-70.0), contact with a person thought to have giardiasis (OR = 2.3; CI, 1.4-36.0), and recent contact with a child in day care (OR = 1.5; CI, 1.0-2.1). Multivariate modeling supported these associations. Shallow wells, relatively common in New Hampshire, have not previously been established as important sources of giardiasis.
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PMID:Endemic giardiasis in New Hampshire: a case-control study of environmental risks. 850 29


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