Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0017536 (
giardiasis
)
1,714
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Symptoms of
giardiasis
vary widely - partly owing to host characteristics and partly, perhaps, to different 'strains' of the parasite. In parallel, the immune response to Giardia also varies - involving humoral and cellular components both in the serum and the intestinal mucosa. In this article, Neal denHollander, Doone Riley and Dean Befus take a critical look at accumulating information about Giardia immunology, and discuss how the miscellany of factors may contribute to the
immunopathology
of the disease.
...
PMID:Immunology of giardiasis. 1546 65
Giardia lamblia is one of the most common infectious protozoans in the world. Giardia rarely causes severe life-threatening diarrhea, and may even have a slight protective effect in this regard, but it is a major contributor to malnutrition and growth faltering in children in the developing world. Giardia infection also appears to be a significant risk factor for postinfectious irritable bowel and chronic fatigue syndromes. In this review we highlight recent work focused on the impact of
giardiasis
and the mechanisms that contribute to the various outcomes of this infection, including changes in the composition of the microbiota, activation of immune responses, and
immunopathology
.
...
PMID:The Intersection of Immune Responses, Microbiota, and Pathogenesis in Giardiasis. 2883 Jun 65
