Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0017536 (giardiasis)
 1,714 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In patients with chronic diarrhoea investigations exceptionally reveal a common variable hypogammaglobulinaemia. A 42-year old man presenting with chronic bronchitis and asymptomatic post-hepatitis B cirrhosis was hospitalized for evaluation of a chronic diarrhoea accompanied by altered general condition. Investigations detected global hypogammaglobulinaemia, diffuse lymphoid hyperplasia of the small bowel, and lambliasis. Treatment with gammaglobulins and antibiotics resulted in disappearance of symptoms. This was a rare disease due to a primary disorder where global hypogammaglobulinaemia was associated with a normal number of circulating B-cells. Prognosis was cautious in view of the risk of malignant proliferation.
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PMID:[Common variable hypogammaglobulinemia. A rare cause of chronic diarrhea. A case]. 827 24

Diffuse nodular lymphoid hyperplasia of the gastrointestinal tract is a rare disease characterized by numerous small polypoid nodules in the small intestine, large intestine, or both. It is associated with immunodeficiency and infection, such as Giardia lamblia and Helicobacter pylori. Although diffuse nodular lymphoid hyperplasia associated with common variable immunodeficiency (CVID) and giardiasis is already known, a few studies have reported a regression of the lymphoid nodules after the eradication of infection. We herein describe a case of diffuse nodular lymphoid hyperplasia of the intestine associated with CVID and refractory giardiasis that markedly improved after successfully treating giardiasis.
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PMID:Diffuse Nodular Lymphoid Hyperplasia of the Intestine Caused by Common Variable Immunodeficiency and Refractory Giardiasis. 2815 71