Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0017536 (giardiasis)
 1,714 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We report an association between giardiasis and chronic urticaria and review the few previous cases in the literature. An unusual aspect of our case was the intensification of the urticarial response with antiprotozoal chemotherapy. We discuss the clinical features in terms of the limited current knowledge concerning immunologic mechanisms in giardiasis and the antigenic structure of Giardia lamblia.
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PMID:Giardiasis causing urticaria in a child. 686 35

Three patients with chronic urticaria or pruritus were found to suffer from an asymptomatic intestinal infection caused by the protozoan Giardia lamblia. Treatment with metronidazole per os or tinidazole per os was successful; the pruritic symptoms in one patient improved markedly.Giardia lamblia (Giardia intestinalis) are enteroparasites and produce gastrointestinal symptoms such as acute and chronic diarrhea. Cutaneous manifestations associated with giardiasis occur extremely rarely. Urticaria and itching may be explained as an infection-associated allergy. Hitherto, the following cutaneous signs have been described: urticaria, angioedema, mouth ulcers, pruritus, atopic dermatitis, and anal eczema.We considered that the cutaneous manifestations described here, i. e., urticaria and itching, were secondary to the associated gastrointestinal infection due to Giardia lamblia cysts and trophozoite forms, as they disappeared under specific treatment with metronidazole or tinidazole.
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PMID:[Giardia lamblia--cause of urticaria and pruritus or accidental association?]. 1587 47

We report the case of a 56-year-old female who suffers from chronic urticaria and digestive symptoms, suggesting parasitic infection. Neither repetitive ova and parasite examinations in stools, nor duodenal aspiration examination reveals any parasite. The patient is treated by tinidazole, but the symptoms reappear ten days later. An additive ELISA test on stool remains positive for Giardia Lamblia; the patient receives once more tinidazole and symptoms totally disappear. This case report illustrates that the association between urticaria and digestive symptoms should guide the clinician to the diagnosis of Giardia Lamblia infection, and it shows the importance of a rapid and highly sensitive diagnostic test for giardiasis, like the ELISA test.
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PMID:Chronic urticaria in a middle-aged woman. 2066 87