Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0017168 (gastroesophageal reflux disease)
 11,783 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
ADRACALIN 11.4
CAGR1 10.1
ALTE 9.6
Methylmalonate semialdehyde dehydrogenase 9.4
calpain 14 9.4
proton pump 9.0
Midline-1 8.8
CAPN14 8.8
ENaCdelta 8.6
MAS-related G protein-coupled receptor 8.4
NOX5 protein 8.4
SSR4 8.4
BRAVO 8.2
SMA3 8.2
HSAN II 8.2
LIN1 8.1
FHL1B 8.1
AKIRIN2 8.1
basonuclin 2 7.9
LIN2 7.9
KRT23 7.8
Eotaxin-3 7.7
RIMS1 7.7
GOR 7.6
KEAP1 protein 7.6
PPP2R5B 7.6
chromodomain helicase DNA binding protein 7 7.6
NADPH oxidase 5 7.5
EPC2 7.4
ZNF292 7.3
SLC5A6 7.3
KIAA2022 7.3
PACS1 7.3
ALDH6A1 7.2
MUC3A 7.2
PDZRN3 7.2
FRE 7.1
HSAN1 7.0
ADAT3 7.0
KRT4 6.9
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Disease
gastroesophageal reflux disease 11.4
Nonspecific esophageal motility disorder 11.4
Xiphoid syndrome 11.4
Other esophageal disorders 11.4
Cricopharyngeal spasm 10.8
Erosive esophagitis 10.7
Sandifer syndrome 10.7
Bile Reflux 10.4
Familial visceral neuropathy 10.4
Aneurysm of ascending aorta 10.4
Reactive gastropathy 10.4
Pangastritis 10.4
Cricopharyngeal incoordination 10.4
Laryngopharyngeal reflux 10.1
Esophageal atresia/tracheoesophageal fistula 10.1
Drug-induced esophagitis 10.1
Sliding hiatal hernia 10.0
Reflux esophagitis 10.0
hiatal hernia 9.9
chalasia 9.9
esophageal dysmotility 9.9
reflux esophagitis 9.8
Recurrent chest infections 9.8
Nutcracker esophagus 9.8
Gastric motor dysfunction 9.8
Diabetic diarrhea 9.8
Adenocarcinoma of the cardia 9.8
Esophageal erosions 9.8
esophagitis 9.8
Recurrent aspiration pneumonia 9.6
Esophageal adenocarcinoma 9.5
Barrett's esophagus 9.4
Diabetic gastropathy 9.4
Other respiratory disorders 9.4
Gastric hypomotility 9.4
Eosinophilic esophagitis 9.3
laryngitis 9.3
esophageal spasm 9.2
cough variant asthma 9.1
Pill esophagitis 9.1
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Symptom
Esophageal chest pain 11.4
Projectile vomiting 11.4
Intermittent torticollis 11.4
Dysphagia (difficulty swallowing) 11.4
acid regurgitation 10.8
waterbrash 10.4
sternalgia 10.4
heartburn 10.3
Non-cardiac chest pain 10.3
Esophageal pain 9.8
postnasal drip 9.8
ENT symptoms 9.6
belching 9.2
Nasal regurgitation 9.1
Early satiety 8.9
Globus sensation 8.9
Chest wall pain 8.8
chronic cough 8.8
nocturnal cough 8.7
Regurgitation 8.5
retrosternal discomfort 8.3
Bilious vomiting 8.2
Throat symptoms 8.2
Chronic chest pain 8.1
Airway constriction 7.9
muscular incoordination 7.9
Homan's sign 7.8
Night pain 7.8
Poor weight gain 7.8
Persistent vomiting 7.7
regurgitation 7.5
Floppy 7.4
Retrosternal pain 7.4
Chest discomfort 7.4
persistent cough 7.3
Burning pain 7.2
Infantile colic 7.1
Thoracic pain 7.1
Respiratory abnormalities 7.0
bloating 6.9
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Drug
Pariet 10.3
Protonix 10.2
Pantoprazole sodium 10.1
Nexium 9.8
Tenatoprazole 9.4
Itopride hydrochloride 9.4
Roxatidine acetate hydrochloride 9.4
Propulsid 9.4
Cisapride 8.6
Omeprazole 8.3
Primperan 8.0
Dramamine 7.7
Dimethicone 7.5
Zinga 7.5
Sevelamer carbonate 7.5
Tilade 7.3
Histalog 7.3
Darvon 7.2
Riopan 7.0
Clebopride 7.0
Thioproline 7.0
Carafate 6.9
Sincalide 6.9
Gastrozepin 6.8
Alendronate sodium 6.8
Gastro 6.7
Buscopan 6.7
Histalog 6.5
Sucralfate 6.5
Polaprezinc 6.4
Metoclopramide hydrochloride 6.4
Tegaserod 6.3
Gastrozepin 6.2
Plaquenil 6.0
Tegaserod 6.0
Plaquenil 6.0
Maalox 6.0
Rioprostil 5.9
CEG 5.9
Norcuron 5.9
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Enzyme
GDP-L-fucose synthase 8.1
PHOSPHO1 5.9
GDP-mannose 4,6-dehydratase 5.8
pepsin 5.3
methylcrotonyl-CoA carboxylase 4.9
gastricsin 4.8
SOR 4.4
PFI 3.8
PMT 3.8
pantothenate kinase 3.5
urease 3.4
urease 3.3
myrosinase 3.2
CDH 3.2
H,K-ATPase 3.2
LIS 3.1
phosphoglycerate dehydrogenase 3.1
Fpg protein 3.0
SOR 2.9
PAT 2.7
ornithine transcarbamylase 2.7
CYP3A4 2.5
BAL 2.5
TRS 2.4
lactase 2.3
tryptase 2.3
arylsulfatase A 2.1
p-nitrophenylphosphatase 2.1
NAT 2.0
GCA 2.0
glucocerebrosidase 1.9
MCS 1.8
GABA transaminase 1.7
galactose oxidase 1.7
PST 1.7
12-lipoxygenase 1.7
KAT 1.6
AOR 1.6
SPT 1.6
ACE 1.6
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Compound
Rabeprazole 9.8
Difenoxin 9.4
Diphemanil 9.1
Pantoprazole 8.9
Rabeprazole sodium 8.9
Cisapride 8.6
Omeprazole 8.1
Lansoprazole 7.9
Nizatidine 7.7
Myosmine 7.5
PPI 7.4
Bethanechol 7.3
Acotiamide 7.2
Metoclopramide hydrochloride 7.1
Metoclopramide 6.7
Glycochenodeoxycholic acid 6.6
Sudan Red 6.6
Sucralfate 6.5
6-pyruvoyltetrahydropterin 6.4
Germin 6.1
barium 6.1
Ranitidine 6.0
Domperidone 5.9
Delavirdine 5.9
Lubiprostone 5.9
8-HETE 5.8
Prochlorperazine 5.8
Baclofen 5.8
Dimenhydrinate 5.6
2-methoxybenzamide 5.5
Lithocholic acid 5.3
DCI 5.2
TIF 5.2
Prone 4.8
Sodium deoxycholate 4.8
Atropine sulfate 4.7
APO 4.7
Paricalcitol 4.6
Chenodeoxycholic acid 4.6
Glycopyrrolate 4.6
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