Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0017168 (gastroesophageal reflux disease)
11,783 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
proton pump 1497
Sep 774
She 111
gastrin 111
gut 105
reserved 95
Pol 67
Mol 67
FRE 59
collagen 52
insulin 46
ATPase 45
cytokine 44
p53 43
ENT 42
ENG 41
CYP2C19 40
IgE 40
GABA 37
IL-8 32
MRI 28
IL-6 28
cytochrome P450 27
cholecystokinin 26
calcium channel 25
substance P 25
COPD 24
mucin 23
ghrelin 23
tumor necrosis factor 22
leptin 22
histamine H2 receptor 20
B12 20
cyclooxygenase-2 19
TNF 18
hemoglobin 18
SPA 18
GABA(B) receptor 18
COX-2 18
FEV 18
more...
Disease
gastroesophageal reflux disease 11783
esophagitis 1879
Barrett's esophagus 1385
dysphagia 1075
Esophageal 983
adenocarcinoma 887
asthma 857
cancer 707
hiatal hernia 705
reflux esophagitis 515
obesity 479
achalasia 456
dyspepsia 437
dysplasia 398
Esophagus 380
Esophagus 380
peptic ulcer 365
carcinoma 263
gastritis 256
tumor 243
hernia 216
gastric cancer 197
Helicobacter pylori infection 193
diabetes 183
esophageal cancer 177
pneumonia 176
esophageal atresia 175
esophageal cancer 167
irritable bowel syndrome 166
Esophageal adenocarcinoma 165
failure to thrive 163
duodenal ulcer 155
esophageal dysmotility 150
hypertension 149
laryngitis 142
esophageal stricture 141
Heller 132
Eosinophilic esophagitis 129
depression 127
obstructive sleep apnea 118
more...
Symptom
heartburn 1019
regurgitation 564
vomiting 528
cough 480
chest pain 462
pain 431
chronic cough 327
abdominal pain 189
constipation 174
anesthesia 163
diarrhea 154
acidity 153
nausea 134
hoarseness 115
discomfort 115
discomfort 111
acid regurgitation 109
dyspnea 105
wheezing 105
seizures 94
belching 93
epigastric pain 84
postnasal drip 83
bloating 76
stridor 65
respiratory distress 60
angina 60
overweight 50
hypotonia 46
ENT 42
erythema 39
headache 37
anorexia 37
spasm 36
persistent cough 36
fatigue 33
sore throat 31
nausea and vomiting 30
weakness 29
cyanosis 29
more...
Drug
Asthma 143
Omeprazole 118
Cardiovasc 88
Cisapride 48
ENT 42
Gastro 36
Ranitidine 24
caffeine 18
Cimetidine 15
Cimetidine 14
Monit 13
ascorbate 10
Nexium 10
Histamine 10
lactose 10
Sucralfate 9
Pariet 8
Leaf 8
ROC 7
Domperidone 7
citric acid 7
nitroglycerin 6
DEL 6
Atropine 6
Theophylline 6
Primperan 6
Dial 6
Allergen 6
CSF 6
Botox 6
ROS 5
Azithromycin 5
Pantoprazole sodium 5
ampicillin 5
Misoprostol 4
OTC 4
OTC 4
ADM 4
Gel 3
Dermatol 3
more...
Enzyme
pepsin 129
ATPase 57
urease 28
urease 28
trypsin 27
ACE 20
mitogen-activated protein kinase 17
ERK 17
CYP3A4 13
phosphodiesterase 11
peroxidase 10
superoxide dismutase 7
catalase 7
protein kinase C 7
alanine aminotransferase 6
lipase 6
aspartate aminotransferase 6
APC 5
tryptase 5
glutathione peroxidase 5
NO synthase 5
BAL 4
lactase 4
NADPH oxidase 4
NOS 4
ornithine transcarbamylase 4
NADPH oxidase 4
acetylcholinesterase 4
MEK 4
protein kinase 4
glutathione S-transferase 3
MIP 3
CAD 3
CAD 3
CAD 3
ACS 3
NADPH-diaphorase 3
luciferase 3
NQO1 3
focal adhesion kinase 3
more...
Compound
Clin 1205
Dec 802
barium 401
water 170
PPI 135
Omeprazole 122
oxygen 112
DNA 92
nitric oxide 85
calcium 78
sodium 69
potassium 63
His 59
glucose 59
HCl 57
hydrogen 55
Cisapride 46
CO2 39
Rabeprazole 39
GABA 37
GABA 37
iron 33
urea 31
salt 30
ethanol 30
Metoclopramide 28
Lansoprazole 26
acetate 26
Pantoprazole 25
Baclofen 25
Optimal 23
Ranitidine 22
sulfate 21
phosphate 20
Cardiol 19
TNF 18
glutamate 18
caffeine 18
ASA 18
bromide 15
more...