Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0017168 (
gastroesophageal reflux disease
)
11,783
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
proton pump
1497
Sep
774
She
111
gastrin
111
gut
105
reserved
95
Pol
67
Mol
67
FRE
59
collagen
52
insulin
46
ATPase
45
cytokine
44
p53
43
ENT
42
ENG
41
CYP2C19
40
IgE
40
GABA
37
IL-8
32
MRI
28
IL-6
28
cytochrome P450
27
cholecystokinin
26
calcium channel
25
substance P
25
COPD
24
mucin
23
ghrelin
23
tumor necrosis factor
22
leptin
22
histamine H2 receptor
20
B12
20
cyclooxygenase-2
19
TNF
18
hemoglobin
18
SPA
18
GABA(B) receptor
18
COX-2
18
FEV
18
more...
Disease
gastroesophageal reflux disease
11783
esophagitis
1879
Barrett's esophagus
1385
dysphagia
1075
Esophageal
983
adenocarcinoma
887
asthma
857
cancer
707
hiatal hernia
705
reflux esophagitis
515
obesity
479
achalasia
456
dyspepsia
437
dysplasia
398
Esophagus
380
Esophagus
380
peptic ulcer
365
carcinoma
263
gastritis
256
tumor
243
hernia
216
gastric cancer
197
Helicobacter pylori infection
193
diabetes
183
esophageal cancer
177
pneumonia
176
esophageal atresia
175
esophageal cancer
167
irritable bowel syndrome
166
Esophageal adenocarcinoma
165
failure to thrive
163
duodenal ulcer
155
esophageal dysmotility
150
hypertension
149
laryngitis
142
esophageal stricture
141
Heller
132
Eosinophilic esophagitis
129
depression
127
obstructive sleep apnea
118
more...
Symptom
heartburn
1019
regurgitation
564
vomiting
528
cough
480
chest pain
462
pain
431
chronic cough
327
abdominal pain
189
constipation
174
anesthesia
163
diarrhea
154
acidity
153
nausea
134
hoarseness
115
discomfort
115
discomfort
111
acid regurgitation
109
dyspnea
105
wheezing
105
seizures
94
belching
93
epigastric pain
84
postnasal drip
83
bloating
76
stridor
65
respiratory distress
60
angina
60
overweight
50
hypotonia
46
ENT
42
erythema
39
headache
37
anorexia
37
spasm
36
persistent cough
36
fatigue
33
sore throat
31
nausea and vomiting
30
weakness
29
cyanosis
29
more...
Drug
Asthma
143
Omeprazole
118
Cardiovasc
88
Cisapride
48
ENT
42
Gastro
36
Ranitidine
24
caffeine
18
Cimetidine
15
Cimetidine
14
Monit
13
ascorbate
10
Nexium
10
Histamine
10
lactose
10
Sucralfate
9
Pariet
8
Leaf
8
ROC
7
Domperidone
7
citric acid
7
nitroglycerin
6
DEL
6
Atropine
6
Theophylline
6
Primperan
6
Dial
6
Allergen
6
CSF
6
Botox
6
ROS
5
Azithromycin
5
Pantoprazole sodium
5
ampicillin
5
Misoprostol
4
OTC
4
OTC
4
ADM
4
Gel
3
Dermatol
3
more...
Enzyme
pepsin
129
ATPase
57
urease
28
urease
28
trypsin
27
ACE
20
mitogen-activated protein kinase
17
ERK
17
CYP3A4
13
phosphodiesterase
11
peroxidase
10
superoxide dismutase
7
catalase
7
protein kinase C
7
alanine aminotransferase
6
lipase
6
aspartate aminotransferase
6
APC
5
tryptase
5
glutathione peroxidase
5
NO synthase
5
BAL
4
lactase
4
NADPH oxidase
4
NOS
4
ornithine transcarbamylase
4
NADPH oxidase
4
acetylcholinesterase
4
MEK
4
protein kinase
4
glutathione S-transferase
3
MIP
3
CAD
3
CAD
3
CAD
3
ACS
3
NADPH-diaphorase
3
luciferase
3
NQO1
3
focal adhesion kinase
3
more...
Compound
Clin
1205
Dec
802
barium
401
water
170
PPI
135
Omeprazole
122
oxygen
112
DNA
92
nitric oxide
85
calcium
78
sodium
69
potassium
63
His
59
glucose
59
HCl
57
hydrogen
55
Cisapride
46
CO2
39
Rabeprazole
39
GABA
37
GABA
37
iron
33
urea
31
salt
30
ethanol
30
Metoclopramide
28
Lansoprazole
26
acetate
26
Pantoprazole
25
Baclofen
25
Optimal
23
Ranitidine
22
sulfate
21
phosphate
20
Cardiol
19
TNF
18
glutamate
18
caffeine
18
ASA
18
bromide
15
more...